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Protein

RPW8-like protein 4

Gene

HR4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable disease resistance (R) protein.Curated

Miscellaneous

Ecotypes susceptible to Erysiphe cichoracearum, such as cv. Columbia, are lacking RPW8.1 and RPW8.2 but contain in place HR4.2 Publications

GO - Biological processi

  • plant-type hypersensitive response Source: UniProtKB-KW
  • response to bacterium Source: UniProtKB
  • response to ethylene Source: UniProtKB
  • response to external biotic stimulus Source: UniProtKB
  • response to fungus Source: UniProtKB
  • response to jasmonic acid Source: UniProtKB
  • response to salicylic acid Source: UniProtKB
  • response to symbiotic bacterium Source: UniProtKB
  • response to symbiotic fungus Source: UniProtKB

Keywordsi

Biological processHypersensitive response, Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
RPW8-like protein 4
Short name:
AtHR41 Publication
Gene namesi
Name:HR4
Ordered Locus Names:At3g50480Imported
ORF Names:T20E23.80Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G50480
TAIRilocus:2098740 AT3G50480

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 29HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004316741 – 200RPW8-like protein 4Add BLAST200

Proteomic databases

PaxDbiQ9SCS6

Expressioni

Inductioni

Expressed in leaves after powdery mildew infection (e.g. Erysiphe cichoracearum UCSC1) (PubMed:15155802). Accumulates upon oviposition by pierid butterflies (e.g. Pieris brassicae) (PubMed:17142483). Induced in seedlings by the beneficial symbiotic fungus Trichoderma atroviride and, by the plant growth-promoting rhizobacterium (PGPR) Pseudomonas fluorescens after a transient repression (PubMed:22942755). Expressed after infection by the bacterial pathogenic Pseudomonas syringae pv. tomato DC3000 (PubMed:22942755). Triggered by various phytohormones such as ethylene (ET), salicylic acid (SA) and methyl jasmonate (MeJA) (PubMed:22942755).3 Publications

Gene expression databases

ExpressionAtlasiQ9SCS6 baseline and differential
GenevisibleiQ9SCS6 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G50480.1

Structurei

3D structure databases

ProteinModelPortaliQ9SCS6
SMRiQ9SCS6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 157RPW8PROSITE-ProRule annotationAdd BLAST157

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili70 – 127Sequence analysisAdd BLAST58

Sequence similaritiesi

Belongs to the plant RPW8 protein family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410JKFW Eukaryota
ENOG411170I LUCA
OrthoDBiEOG09360OG6
PhylomeDBiQ9SCS6

Family and domain databases

InterProiView protein in InterPro
IPR008808 Powdery_mildew-R_dom
PfamiView protein in Pfam
PF05659 RPW8, 1 hit
PROSITEiView protein in PROSITE
PS51153 RPW8, 1 hit

Sequencei

Sequence statusi: Complete.

Q9SCS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIAELAVIK TVGGPLIAAA LGVGAQVIYD GFRKGKDTSI INRLGRTMES
60 70 80 90 100
ISPVRDRIGK LSNVEGKPFR EVHESLTRLL EDAKSIIEKY WKLRWSRHVC
110 120 130 140 150
RKYRYIKKLE SIELELVRVA REIQVHQWTD IKEMKAIQVH QWTDIKEMKA
160 170 180 190 200
IQVDQWTDIK EMKAIQVDQW IDIKEMKAIQ VDQWTDIKEM KAQISEKHNK
Length:200
Mass (Da):23,389
Last modified:May 1, 2000 - v1
Checksum:i6D18726A79A3C679
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti118R → W in BAF01383 (Ref. 5) Curated1
Sequence conflicti198 – 200HNK → Q in BAD94912 (Ref. 5) Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ267632 Genomic DNA Translation: ACJ05894.1
AL133363 Genomic DNA Translation: CAB62477.1
CP002686 Genomic DNA Translation: AEE78671.1
AF361849 mRNA Translation: AAK32861.1
BT000848 mRNA Translation: AAN38685.1
AK220594 mRNA Translation: BAD94912.1
AK229528 mRNA Translation: BAF01383.1
PIRiT46079
RefSeqiNP_566933.1, NM_114908.5
UniGeneiAt.66512

Genome annotation databases

EnsemblPlantsiAT3G50480.1; AT3G50480.1; AT3G50480
GeneIDi824212
GrameneiAT3G50480.1; AT3G50480.1; AT3G50480
KEGGiath:AT3G50480

Similar proteinsi

Entry informationi

Entry nameiHR4_ARATH
AccessioniPrimary (citable) accession number: Q9SCS6
Secondary accession number(s): Q0WNB7, Q570W3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 7, 2015
Last sequence update: May 1, 2000
Last modified: April 25, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health