UGT85B1

Functionⁱ

Involved in the biosynthesis of the cyanogenic glucoside dhurrin. Prevents the dissociation and release of toxic hydrogen cyanide. Mandelonitrile, p-hydroxymandelonitrile, benzyl alcohol, benzoic acid and geraniol, but not hydroquinone(1,4-benzenediol), alpha-terpinol, linalool or farnesol are utilized as acceptor substrates. UDP-glucose, but not UDP-xylose or UDP-glucuronic acid can be used as sugar donor.3 Publications

Catalytic activityⁱ

UDP-D-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxymandelonitrile beta-D-glucoside.

Enzyme regulationⁱ

Inhibited by p-hydroxybenzaldehyde.

Kineticsⁱ

K_M=
0.14 mM for geraniol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
0.13 mM for beta-citronellol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
1.13 mM for nerol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
0.66 mM for 1-hexanol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
0.73 mM for cis-3-hexen-1-ol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
0.84 mM for mandelonitrile
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
6.33 mM for 2-hydroxy-3-methoxybenzyl alcohol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
0.69 mM for 3-methyl-3-buten-1-ol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
10.3 mM for 3-methyl-2-buten-1-ol
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
K_M=
0.8 mM for UDP-glucose
2 Publications
Manual assertion based on experiment inⁱ
- Ref.3
  "The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor."
  Hansen K.S., Kristensen C., Tattersall D.B., Jones P.R., Olsen C.E., Bak S., Moeller B.L.
  Phytochemistry 64:143-151(2003) [PubMed] [Europe PMC] [Abstract]
  Cited for: BIOPHYSICOCHEMICAL PROPERTIES.
- Ref.4
  "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses."
  Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L.
  Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract]
  Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.

Pathwayⁱ: dhurrin biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes dhurrin from L-tyrosine.
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

Tyrosine N-monooxygenase (CYP79A1)
4-hydroxyphenylacetaldehyde oxime monooxygenase (CYP71E1)
Cyanohydrin beta-glucosyltransferase (UGT85B1)

This subpathway is part of the pathway dhurrin biosynthesis, which is itself part of Secondary metabolite biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes dhurrin from L-tyrosine, the pathway dhurrin biosynthesis and in Secondary metabolite biosynthesis.

GO - Molecular functionⁱ

cyanohydrin beta-glucosyltransferase activity Source: UniProtKB-EC

GO - Biological processⁱ

dhurrin biosynthetic process Source: UniProtKB-UniPathway

Complete GO annotation...

Keywords - Molecular functionⁱ

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCycⁱ	MetaCyc:MONOMER-523.
BRENDAⁱ	2.4.1.85. 5768.
SABIO-RK	Q9SBL1.
UniPathwayⁱ	UPA00757; UER00746.

Protein family/group databases

CAZyⁱ	GT1. Glycosyltransferase Family 1.

CAZyⁱ

GT1. Glycosyltransferase Family 1.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cyanohydrin beta-glucosyltransferase (EC:2.4.1.85) Alternative name(s): UDP-glucose-p-hydroxymandelonitrile glucosyltransferase
Gene namesⁱ	Name:UGT85B1 Synonyms:HMNGT
Organismⁱ	Sorghum bicolor (Sorghum) (Sorghum vulgare)
Taxonomic identifierⁱ	4558 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › Liliopsida › Petrosaviidae › commelinids › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogonodae › Andropogoneae › Sorghinae › Sorghum

Subcellular locationⁱ

Cytoplasm
1 Publication
Manual assertion based on experiment inⁱ
- Ref.6
  "Metabolon formation in dhurrin biosynthesis."
  Nielsen K.A., Tattersall D.B., Jones P.R., Moeller B.L.
  Phytochemistry 69:88-98(2008) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION.
Endoplasmic reticulum membrane
1 Publication
Manual assertion based on experiment inⁱ
- Ref.6
  "Metabolon formation in dhurrin biosynthesis."
  Nielsen K.A., Tattersall D.B., Jones P.R., Moeller B.L.
  Phytochemistry 69:88-98(2008) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION.
; Peripheral membrane protein
1 Publication
Manual assertion based on experiment inⁱ
- Ref.6
  "Metabolon formation in dhurrin biosynthesis."
  Nielsen K.A., Tattersall D.B., Jones P.R., Moeller B.L.
  Phytochemistry 69:88-98(2008) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION.
; Cytoplasmic side
1 Publication
Manual assertion based on experiment inⁱ
- Ref.6
  "Metabolon formation in dhurrin biosynthesis."
  Nielsen K.A., Tattersall D.B., Jones P.R., Moeller B.L.
  Phytochemistry 69:88-98(2008) [PubMed] [Europe PMC] [Abstract]
  Cited for: SUBCELLULAR LOCATION.

Note:

In the presence of CYP79A1 and CYP71E1, moves toward the surface of the ER membranes in order to form a metabolon.

GO - Cellular componentⁱ

endoplasmic reticulum membrane Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cytoplasm, Endoplasmic reticulum, Membrane

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	Length	Description
Mutagenesisⁱ	201 – 201	1	R → A: 20-fold reduction in activity. 1 Publication Manual assertion based on experiment inⁱ Ref.4 "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses." Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L. Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract] Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
Mutagenesisⁱ	391 – 391	1	S → A: 185-fold reduction in activity. 1 Publication Manual assertion based on experiment inⁱ Ref.4 "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses." Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L. Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract] Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.
Mutagenesisⁱ	410 – 410	1	E → A: 225-fold reduction in activity. 1 Publication Manual assertion based on experiment inⁱ Ref.4 "Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses." Thorsoee K.S., Bak S., Olsen C.E., Imberty A., Breton C., Moeller B.L. Plant Physiol. 139:664-673(2005) [PubMed] [Europe PMC] [Abstract] Cited for: 3D-STRUCTURE MODELING, BIOPHYSICOCHEMICAL PROPERTIES, MUTAGENESIS OF ARG-201; SER-391 AND GLU-410.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Chainⁱ	1 – 492	492	Cyanohydrin beta-glucosyltransferase		PRO_0000365608	Add BLAST

Post-translational modificationⁱ

The N-terminus is partially blocked.

Expressionⁱ

Gene expression databases

ExpressionAtlasⁱ	Q9SBL1. baseline and differential.

ExpressionAtlasⁱ

Q9SBL1. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	4558.Sb01g001220.1.

STRINGⁱ

4558.Sb01g001220.1.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9SBL1.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Compositional bias

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Compositional biasⁱ	6 – 11	6	Poly-Pro
Compositional biasⁱ	136 – 140	5	Poly-Ala

Sequence similaritiesⁱ

Belongs to the UDP-glycosyltransferase family.Curated

Phylogenomic databases

eggNOGⁱ	KOG1192. Eukaryota. COG1819. LUCA.
HOGENOMⁱ	HOG000237564.
KOⁱ	K13030.
OMAⁱ	DISIWQE.
OrthoDBⁱ	EOG093607YV.

Family and domain databases

InterProⁱ	IPR002213. UDP_glucos_trans. [Graphical view]
PANTHERⁱ	PTHR11926. PTHR11926. 2 hits.
Pfamⁱ	PF00201. UDPGT. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9SBL1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGSNAPPPPT PHVVLVPFPG QGHVAPLMQL ARLLHARGAR VTFVYTQYNY 
        60         70         80         90        100
RRLLRAKGEA AVRPPATSSA RFRIEVIDDG LSLSVPQNDV GGLVDSLRKN 
       110        120        130        140        150
CLHPFRALLR RLGQEVEGQD APPVTCVVGD VVMTFAAAAA REAGIPEVQF 
       160        170        180        190        200
FTASACGLLG YLHYGELVER GLVPFRDASL LADDDYLDTP LEWVPGMSHM 
       210        220        230        240        250
RLRDMPTFCR TTDPDDVMVS ATLQQMESAA GSKALILNTL YELEKDVVDA 
       260        270        280        290        300
LAAFFPPIYT VGPLAEVIAS SDSASAGLAA MDISIWQEDT RCLSWLDGKP 
       310        320        330        340        350
AGSVVYVNFG SMAVMTAAQA REFALGLASC GSPFLWVKRP DVVEGEEVLL 
       360        370        380        390        400
PEALLDEVAR GRGLVVPWCP QAAVLKHAAV GLFVSHCGWN SLLEATAAGQ 
       410        420        430        440        450
PVLAWPCHGE QTTNCRQLCE VWGNGAQLPR EVESGAVARL VREMMVGDLG 
       460        470        480        490 
KEKRAKAAEW KAAAEAAARK GGASWRNVER VVNDLLLVGG KQ

Length:492

Mass (Da):52,916

Last modified:May 1, 2000 - v1

Checksum:ⁱABC6A57AC51E9BE7

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF199453 mRNA. Translation: AAF17077.1.
RefSeqⁱ	XP_002463518.1. XM_002463473.1.
UniGeneⁱ	Sbi.14307.

Genome annotation databases

EnsemblPlantsⁱ	Sb01g001220.1; Sb01g001220.1; Sb01g001220.
GeneIDⁱ	8060874.
Grameneⁱ	Sb01g001220.1; Sb01g001220.1; Sb01g001220.
KEGGⁱ	sbi:SORBI_01g001220.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF199453 mRNA. Translation: AAF17077.1.
RefSeqⁱ	XP_002463518.1. XM_002463473.1.
UniGeneⁱ	Sbi.14307.

3D structure databases

ProteinModelPortalⁱ	Q9SBL1.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	4558.Sb01g001220.1.

STRINGⁱ

4558.Sb01g001220.1.

Protein family/group databases

CAZyⁱ	GT1. Glycosyltransferase Family 1.

CAZyⁱ

GT1. Glycosyltransferase Family 1.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblPlantsⁱ	Sb01g001220.1; Sb01g001220.1; Sb01g001220.
GeneIDⁱ	8060874.
Grameneⁱ	Sb01g001220.1; Sb01g001220.1; Sb01g001220.
KEGGⁱ	sbi:SORBI_01g001220.

Phylogenomic databases

eggNOGⁱ	KOG1192. Eukaryota. COG1819. LUCA.
HOGENOMⁱ	HOG000237564.
KOⁱ	K13030.
OMAⁱ	DISIWQE.
OrthoDBⁱ	EOG093607YV.

Enzyme and pathway databases

UniPathwayⁱ	UPA00757; UER00746.
BioCycⁱ	MetaCyc:MONOMER-523.
BRENDAⁱ	2.4.1.85. 5768.
SABIO-RK	Q9SBL1.

Gene expression databases

ExpressionAtlasⁱ	Q9SBL1. baseline and differential.

ExpressionAtlasⁱ

Q9SBL1. baseline and differential.

Family and domain databases

InterProⁱ	IPR002213. UDP_glucos_trans. [Graphical view]
PANTHERⁱ	PTHR11926. PTHR11926. 2 hits.
Pfamⁱ	PF00201. UDPGT. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

HMNGT_SORBI

Accessionⁱ

Primary (citable) accession number: Q9SBL1

Entry historyⁱ

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	May 1, 2000
Last modified:	September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Direct protein sequencing

Documents

PATHWAY comments
Index of metabolic and biosynthesis pathways
SIMILARITY comments
Index of protein domains and families

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9SBL1 (HMNGT_SORBI)

UniProt

Q9SBL1 - HMNGT_SORBI

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Cyanohydrin beta-glucosyltransferase

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>Describes an enzyme regulatory mechanism and reports the components which regulate (by activation or inhibition) the reaction.</p><p><a href='../manual/enzyme_regulation' target='_top'>More...</a></p>Enzyme regulationi

<p>Describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.</p><p><a href='../manual/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

<p>Describes the metabolic pathway(s) associated with a protein.</p><p><a href='../manual/pathway' target='_top'>More...</a></p>Pathwayi: dhurrin biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Provides information on the disease(s) and phenotype(s) associated with a protein.</p><p><a href='../manual/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

Enzyme regulationⁱ

Kineticsⁱ

Pathwayⁱ: dhurrin biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ