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Protein

Thionin

Gene

THI2

Organism
Brassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Toxin

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Thionin
Cleaved into the following 2 chains:
Gene namesi
Name:THI2
OrganismiBrassica rapa subsp. pekinensis (Chinese cabbage) (Brassica pekinensis)
Taxonomic identifieri51351 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica
Proteomesi
  • UP000011750 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000003414725 – 70ThioninAdd BLAST46
ChainiPRO_000003414871 – 133Acidic proteinSequence analysisAdd BLAST63

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi27 ↔ 64By similarity
Disulfide bondi28 ↔ 56By similarity
Disulfide bondi40 ↔ 50By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed in flowers.

Structurei

3D structure databases

ProteinModelPortaliQ9SBK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiQ9SBK8.

Family and domain databases

Gene3Di3.30.1350.10. 1 hit.
InterProiIPR001010. Thionin.
[Graphical view]
PfamiPF00321. Thionin. 1 hit.
[Graphical view]
PRINTSiPR00287. THIONIN.
SUPFAMiSSF57429. SSF57429. 1 hit.
PROSITEiPS00271. THIONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9SBK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGKTVILGV IIMSLVMAQN QVEAKICCPR TIDRNIYNAC RLTGASMTNC
60 70 80 90 100
ANLSGCKIVS GTTCPPGYTH DILQNYGDAV NEYCKLGCAS SVCGALTTLK
110 120 130
NSMQVNCEGA VSQCTNACSN FCTKGSAKVV ETA
Length:133
Mass (Da):13,961
Last modified:May 1, 2000 - v1
Checksum:i4BBC3A8A8B5CD964
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF090836 mRNA. Translation: AAF21800.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF090836 mRNA. Translation: AAF21800.1.

3D structure databases

ProteinModelPortaliQ9SBK8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiQ9SBK8.

Family and domain databases

Gene3Di3.30.1350.10. 1 hit.
InterProiIPR001010. Thionin.
[Graphical view]
PfamiPF00321. Thionin. 1 hit.
[Graphical view]
PRINTSiPR00287. THIONIN.
SUPFAMiSSF57429. SSF57429. 1 hit.
PROSITEiPS00271. THIONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTHN_BRARP
AccessioniPrimary (citable) accession number: Q9SBK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: May 1, 2000
Last modified: October 5, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.