Reviewed,
UniProtKB/Swiss-Prot Q9SB51 (UBP16_ARATH)
Last modified
November 3, 2009.
Version 56.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Ubiquitin carboxyl-terminal hydrolase 16 EC=3.1.2.15 Alternative name(s): Ubiquitin thioesterase 16 Ubiquitin-specific-processing protease 16 Deubiquitinating enzyme 16 Short name=AtUBP16 | ||||||
| Gene names |
| ||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 1008 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins By similarity. |
| Catalytic activity | Ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol. |
| Subcellular location | Membrane; Single-pass membrane protein Potential. |
| Sequence similarities | Belongs to the peptidase C19 family. Contains 1 MYND-type zinc finger. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Ubl conjugation pathway |
| Cellular component | Membrane |
| Domain | Transmembrane Zinc-finger |
| Ligand | Metal-binding Zinc |
| Molecular function | Hydrolase Protease Thiol protease |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cell proliferation Inferred from genetic interaction. Source: TAIR flower developmentInferred from genetic interaction. Source: TAIR leaf developmentInferred from genetic interaction. Source: TAIR root developmentInferred from genetic interaction. Source: TAIR ubiquitin-dependent protein catabolic processInferred from electronic annotation. Source: InterPro |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | cysteine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW ubiquitin thiolesterase activityInferred from electronic annotation. Source: EC zinc ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 1008 | 1008 | Ubiquitin carboxyl-terminal hydrolase 16 | PRO_0000313042 | |||||
Regions | |||||||||
| Transmembrane | 7 – 27 | 21 | Potential | ||||||
| Zinc finger | 74 – 111 | 38 | MYND-type | ||||||
| Compositional bias | 193 – 365 | 173 | Ser-rich | ||||||
| Compositional bias | 878 – 991 | 114 | Ser-rich | ||||||
Sites | |||||||||
| Active site | 551 | 1 | By similarity | ||||||
| Active site | 796 | 1 | By similarity | ||||||
| Active site | 807 | 1 | By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 183 | 1 | K → N in AAG42757. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The ubiquitin-specific protease family from Arabidopsis. AtUBP1 and 2 are required for the resistance to the amino acid analog canavanine." Yan N., Doelling J.H., Falbel T.G., Durski A.M., Vierstra R.D. Plant Physiol. 124:1828-1843(2000) [PubMed: 11115897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia. |
| [2] | "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana." Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. McCombie W.R.Nature 402:769-777(1999) [PubMed: 10617198] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| AF302666 mRNA. Translation: AAG42757.1. AL035356 Genomic DNA. Translation: CAA23007.1. AL161561 Genomic DNA. Translation: CAB79366.1. | |
| IPI | IPI00518628. |
| PIR | T05578. |
| RefSeq | NP_567705.1. |
| UniGene | At.2551 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1NB8 based on UniProtKB Q93009. |
| ModBase | Search... |
Protein family/group databases | |
| MEROPS | C19.A07. |
Proteomic databases | |
| PRIDE | Q9SB51. |
Genome annotation databases | |
| GeneID | 828558. |
| GenomeReviews | Gene locus AT4G24560 in contig CT486007_GR. |
| KEGG | ath:AT4G24560. |
| NMPDR | fig|3702.1.peg.20352. |
Organism-specific databases | |
| TAIR | At4g24560. |
Phylogenomic databases | |
| OMA | RCKAVRY. |
Enzyme and pathway databases | |
| BRENDA | 3.1.2.15. 302. |
Gene expression databases | |
| ArrayExpress | Q9SB51. |
| Genevestigator | Q9SB51. |
Family and domain databases | |
| InterPro | IPR018200. Pept_C19ubi-hydrolase_C_CS. IPR001394. Peptidase_C19. IPR002893. Znf_MYND. [Graphical view] |
| Pfam | PF00443. UCH. 1 hit. PF01753. zf-MYND. 1 hit. [Graphical view] |
| PROSITE | PS00972. UCH_2_1. 1 hit. PS00973. UCH_2_2. False negative. PS50235. UCH_2_3. 1 hit. PS01360. ZF_MYND_1. 1 hit. PS50865. ZF_MYND_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UBP16_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9SB51 Secondary accession number(s): Q9FPS8 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| Peptidase families Classification of peptidase families and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


