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Q9SAF5 (ALA11_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative phospholipid-transporting ATPase 11
Short name=AtALA11
EC=3.6.3.1
Alternative name(s):
Aminophospholipid flippase 11
Gene names
Name:ALA11
Ordered Locus Names:At1g13210
ORF Names:F3F19.24
OrganismArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length1203 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in transport of phospholipids Potential.

Catalytic activity

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(Out).

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12031203Putative phospholipid-transporting ATPase 11
PRO_0000046395

Regions

Topological domain1 – 7171Cytoplasmic Potential
Transmembrane72 – 9322Helical; Potential
Topological domain94 – 974Extracellular Potential
Transmembrane98 – 12023Helical; Potential
Topological domain121 – 303183Cytoplasmic Potential
Transmembrane304 – 32522Helical; Potential
Topological domain326 – 36338Extracellular Potential
Transmembrane364 – 38118Helical; Potential
Topological domain382 – 921540Cytoplasmic Potential
Transmembrane922 – 94120Helical; Potential
Topological domain942 – 95514Extracellular Potential
Transmembrane956 – 97520Helical; Potential
Topological domain976 – 100530Cytoplasmic Potential
Transmembrane1006 – 102823Helical; Potential
Topological domain1029 – 104113Extracellular Potential
Transmembrane1042 – 106423Helical; Potential
Topological domain1065 – 10706Cytoplasmic Potential
Transmembrane1071 – 109121Helical; Potential
Topological domain1092 – 110817Extracellular Potential
Transmembrane1109 – 113325Helical; Potential
Topological domain1134 – 120370Cytoplasmic Potential

Sites

Active site42914-aspartylphosphate intermediate By similarity
Metal binding8661Magnesium By similarity
Metal binding8701Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9SAF5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: D06ED2FBA046FC6E

FASTA1,203136,584
        10         20         30         40         50         60 
MTKCRRRRLH LSNIYAFKGR KSNFQEDHSH IGGPGFSRVV YCNEPNSPAA ERRNYVGNYV 

        70         80         90        100        110        120 
RSTKYTLASF IPKSLFEQFR RVANFYFLVT GVLSLTALSP YSPISALLPL TFVIAASMVK 

       130        140        150        160        170        180 
EAIEDWGRKK QDIEMNNRKV KVHDGNGIFR REGWRDLKVG NIVRVEKDEF FPADLLLLSS 

       190        200        210        220        230        240 
SYEDSICYVE TMNLDGETNL KVKQGLEATS SALHEDSDFK ELKAVVKCED PNADLYTFVG 

       250        260        270        280        290        300 
TLHFEEQRLP LSITQLLLRD SKLRNTEYIY GVVVFTGHDT KVIQNSTDPP SKRSRIERKM 

       310        320        330        340        350        360 
DKIIYLMFGV VFLMSFIGSI VFGIETREDR VRNGGRTERW YLRPDNADIF FDPDRAPMAA 

       370        380        390        400        410        420 
VYHFFTAVML YSYFIPISLY VSIEIVKVLQ SLFINNDILM YYEENDKPAH ARTSNLNEEL 

       430        440        450        460        470        480 
GMVDTILSDK TGTLTCNSME FIKCSIAGTA YGRGITEVER SMAMRSNGSS LVGDDLDVVV 

       490        500        510        520        530        540 
DQSGPKIKGF NFLDERVMKG NWVKQRDAAV LQKFFRLLAV CHTAIPETDE ATGSVSYEAE 

       550        560        570        580        590        600 
SPDEAAFVVA AREFGFEFFS RTQNGISFRE LDLASGKTVE RVYRLLNVLE FNSARKRMSV 

       610        620        630        640        650        660 
IVRDEDGRLL LLSKGADNVM FERLAKNGRK FEEKTREHVN EYADAGLRTL ILAYREVDEN 

       670        680        690        700        710        720 
EYIEFSKNFN EAKNSVTADR ESLIDEITEQ MERDLILLGA TAVEDKLQNG VPDCIDKLAQ 

       730        740        750        760        770        780 
AGIKIWVLTG DKMETAINIG FACSLLRQEM KQIIINLETP HIKALEKAGE KDAIEHASRE 

       790        800        810        820        830        840 
SVVNQMEEGK ALLTASSSAS SHEAFALIID GKSLTYALED DFKKKFLDLA TGCASVICCR 

       850        860        870        880        890        900 
SSPKQKALVT RLVKSGTGKT TLAIGDGAND VGMLQEADIG VGISGVEGMQ AVMSSDIAIA 

       910        920        930        940        950        960 
QFRYLERLLL VHGHWCYSRI SSMICYFFYK NITFGVTVFL YEAYTSFSAQ PAYNDWFLSL 

       970        980        990       1000       1010       1020 
FNVFFSSLPV IALGVFDQDV SARYCYKFPL LYQEGVQNLL FSWKRIIGWM FNGVFTALAI 

      1030       1040       1050       1060       1070       1080 
FFLCKESLKH QLYNPNGKTA GREILGGTMY TCVVWVVNLQ MALAISYFTW LQHIVIWGSV 

      1090       1100       1110       1120       1130       1140 
AFWYIFLMIY GAITPSFSTD AYKVFIEALA PAPSYWLTTL FVMFFALIPF FVFKSVQMRF 

      1150       1160       1170       1180       1190       1200 
FPGYHQMIQW IRYEGHSNDP EFVEMVRQRS IRPTTVGFTA RRAASVRRSG RFHDQLNKNF 


IAF

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed: 11130712] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC007357 Genomic DNA. Translation: AAD31074.1.
CP002684 Genomic DNA. Translation: AEE28985.1.
AY099862 mRNA. Translation: AAM20713.1.
IPIIPI00534449.
PIRF86266.
RefSeqNP_172780.1. NM_101192.2.
UniGeneAt.27871.

3D structure databases

ProteinModelPortalQ9SAF5.
SMRQ9SAF5. Positions 840-901.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9SAF5.

Proteomic databases

PRIDEQ9SAF5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G13210.1; AT1G13210.1; AT1G13210.
GeneID837881.
GenomeReviewsGene locus AT1G13210 in contig CT485782_GR.
KEGGath:AT1G13210.
NMPDRfig|3702.1.peg.1590.

Organism-specific databases

TAIRAt1g13210.

Phylogenomic databases

GeneTreeEPGT00070000028188.
HOGENOMHBG745019.
InParanoidQ9SAF5.
OMAFINNDIL.
PhylomeDBQ9SAF5.
ProtClustDBCLSN2679593.

Gene expression databases

ArrayExpressQ9SAF5.
GenevestigatorQ9SAF5.
GermOnlineAT1G13210. Arabidopsis thaliana.

Family and domain databases

InterProIPR023306. ATPase_cation_domN.
IPR008250. ATPase_P-typ_ATPase-assoc-dom.
IPR023300. ATPase_P-typ_cyto_domA.
IPR023299. ATPase_P-typ_cyto_domN.
IPR001757. ATPase_P-typ_ion-transptr.
IPR018303. ATPase_P-typ_P_site.
IPR006539. ATPase_P-typ_Plipid-transl.
IPR023214. HAD-like_dom.
[Graphical view]
Gene3DG3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits.
G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 2 hits.
G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
KOK01530.
PfamPF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
SUPFAMSSF81660. ATPase_cation_domN. 1 hit.
SSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01652. ATPase-Plipid. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALA11_ARATH
AccessionPrimary (citable) accession number: Q9SAF5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 2000
Last modified: December 14, 2011
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents