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Protein

Probable protein phosphatase 2C 6

Gene

At1g16220

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi100 – 1001Manganese 1By similarity
Metal bindingi100 – 1001Manganese 2By similarity
Metal bindingi101 – 1011Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi321 – 3211Manganese 2By similarity
Metal bindingi367 – 3671Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G16220-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 6 (EC:3.1.3.16)
Short name:
AtPP2C06
Gene namesi
Ordered Locus Names:At1g16220
ORF Names:F3O9.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G16220.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 491491Probable protein phosphatase 2C 6PRO_0000367938Add
BLAST

Proteomic databases

PaxDbiQ9SA22.
PRIDEiQ9SA22.

Expressioni

Gene expression databases

GenevestigatoriQ9SA22.

Structurei

3D structure databases

ProteinModelPortaliQ9SA22.
SMRiQ9SA22. Positions 88-372.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini172 – 336165PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233897.
InParanoidiQ9SA22.
OMAiSEIACLY.
PhylomeDBiQ9SA22.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9SA22-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLCHSKIDK TTRKETGATS TATTTVERQS SGRLRRPRDL YSGGEISEIQ
60 70 80 90 100
QVVGRLVGNG SSEIACLYTQ QGKKGTNQDA MLVWENFCSR SDTVLCGVFD
110 120 130 140 150
GHGPFGHMVS KRVRDMLPFT LSTQLKTTSG TEQSSSKNGL NSAPTCVDEE
160 170 180 190 200
QWCELQLCEK DEKLFPEMYL PLKRALLKTC QQMDKELKMH PTINCFCSGT
210 220 230 240 250
TSVTVIKQGK DLVVGNIGDS RAVLATRDQD NALVAVQLTI DLKPDLPSES
260 270 280 290 300
ARIHRCKGRV FALQDEPEVA RVWLPNSDSP GLAMARAFGD FCLKDYGLIS
310 320 330 340 350
VPDINYHRLT ERDQYIILAT DGVWDVLSNK EAVDIVASAP SRDTAARAVV
360 370 380 390 400
DTAVRAWRLK YPTSKNDDCA VVCLFLEDTS AGGTVEVSET VNHSHEESTE
410 420 430 440 450
SVTITSSKDA DKKEEASTET NETVPVWEIK EEKTPESCRI ESKKTTLAEC
460 470 480 490
ISVKDDEEWS ALEGLTRVNS LLSIPRFFSG ELRSSSWRKW L
Length:491
Mass (Da):54,353
Last modified:May 1, 2000 - v1
Checksum:iC8B2FEDD786328AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006341 Genomic DNA. Translation: AAD34674.1.
CP002684 Genomic DNA. Translation: AEE29420.1.
PIRiB86297.
RefSeqiNP_173072.1. NM_101488.1.
UniGeneiAt.51632.

Genome annotation databases

EnsemblPlantsiAT1G16220.1; AT1G16220.1; AT1G16220.
GeneIDi838190.
KEGGiath:AT1G16220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006341 Genomic DNA. Translation: AAD34674.1.
CP002684 Genomic DNA. Translation: AEE29420.1.
PIRiB86297.
RefSeqiNP_173072.1. NM_101488.1.
UniGeneiAt.51632.

3D structure databases

ProteinModelPortaliQ9SA22.
SMRiQ9SA22. Positions 88-372.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ9SA22.
PRIDEiQ9SA22.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G16220.1; AT1G16220.1; AT1G16220.
GeneIDi838190.
KEGGiath:AT1G16220.

Organism-specific databases

TAIRiAT1G16220.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233897.
InParanoidiQ9SA22.
OMAiSEIACLY.
PhylomeDBiQ9SA22.

Enzyme and pathway databases

BioCyciARA:AT1G16220-MONOMER.

Gene expression databases

GenevestigatoriQ9SA22.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C06_ARATH
AccessioniPrimary (citable) accession number: Q9SA22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 2000
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.