Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Heat shock 70 kDa protein 5

Gene

HSP70-5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

  • response to heat Source: UniProtKB
  • response to virus Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-3371453. Regulation of HSF1-mediated heat shock response.
R-ATH-3371568. Attenuation phase.
R-ATH-3371571. HSF1-dependent transactivation.
R-ATH-6798695. Neutrophil degranulation.
R-ATH-72163. mRNA Splicing - Major Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock 70 kDa protein 5
Alternative name(s):
Heat shock protein 70-5
Short name:
AtHsp70-5
Heat shock protein 70b
Gene namesi
Name:HSP70-5
Synonyms:HSP70B
Ordered Locus Names:At1g16030
ORF Names:T24D18.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G16030.

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: TAIR
  • chloroplast Source: TAIR
  • membrane Source: TAIR
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00004154242 – 646Heat shock 70 kDa protein 5Add BLAST645

Proteomic databases

PaxDbiQ9S9N1.
PRIDEiQ9S9N1.

Expressioni

Inductioni

By heat shock. Up-regulated by virus infection.2 Publications

Gene expression databases

GenevisibleiQ9S9N1. AT.

Interactioni

Protein-protein interaction databases

BioGridi23414. 8 interactors.
IntActiQ9S9N1. 3 interactors.
STRINGi3702.AT1G16030.1.

Structurei

3D structure databases

ProteinModelPortaliQ9S9N1.
SMRiQ9S9N1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
HOGENOMiHOG000228135.
InParanoidiQ9S9N1.
KOiK03283.
OMAiGGMPTDG.
OrthoDBiEOG093604KP.
PhylomeDBiQ9S9N1.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9S9N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATKSEKAIG IDLGTTYSCV GVWMNDRVEI IPNDQGNRTT PSYVAFTDTE
60 70 80 90 100
RLIGDAAKNQ VALNPQNTVF DAKRLIGRKF SDPSVQSDIL HWPFKVVSGP
110 120 130 140 150
GEKPMIVVSY KNEEKQFSPE EISSMVLVKM KEVAEAFLGR TVKNAVVTVP
160 170 180 190 200
AYFNDSQRQA TKDAGAISGL NVLRIINEPT AAAIAYGLDK KGTKAGEKNV
210 220 230 240 250
LIFDLGGGTF DVSLLTIEEG VFEVKATAGD THLGGEDFDN RLVNHFVAEF
260 270 280 290 300
RRKHKKDIAG NARALRRLRT ACERAKRTLS STAQTTIEID SLHEGIDFYA
310 320 330 340 350
TISRARFEEM NMDLFRKCMD PVEKVLKDAK LDKSSVHDVV LVGGSTRIPK
360 370 380 390 400
IQQLLQDFFN GKELCKSINP DEAVAYGAAV QAAILTGEGS EKVQDLLLLD
410 420 430 440 450
VAPLSLGLET AGGVMTVLIP RNTTVPCKKE QVFSTYADNQ PGVLIQVYEG
460 470 480 490 500
ERARTRDNNL LGTFELKGIP PAPRGVPQIN VCFDIDANGI LNVSAEDKTA
510 520 530 540 550
GVKNQITITN DKGRLSKEEI EKMVQDAEKY KAEDEQVKKK VEAKNSLENY
560 570 580 590 600
AYNMRNTIKD EKLAQKLTQE DKQKIEKAID ETIEWIEGNQ LAEVDEFEYK
610 620 630 640
LKELEGICNP IISKMYQGGA AAGGMPTDGD FSSSGAAGGP KIEEVD
Length:646
Mass (Da):70,915
Last modified:May 1, 2000 - v1
Checksum:i46137E1DC9139895
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010924 Genomic DNA. Translation: AAF18501.1.
CP002684 Genomic DNA. Translation: AEE29402.1.
BT001988 mRNA. Translation: AAN71999.1.
BT008401 mRNA. Translation: AAP37760.1.
PIRiB86295.
RefSeqiNP_173055.1. NM_101471.3.
UniGeneiAt.41906.

Genome annotation databases

EnsemblPlantsiAT1G16030.1; AT1G16030.1; AT1G16030.
GeneIDi838174.
GrameneiAT1G16030.1; AT1G16030.1; AT1G16030.
KEGGiath:AT1G16030.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010924 Genomic DNA. Translation: AAF18501.1.
CP002684 Genomic DNA. Translation: AEE29402.1.
BT001988 mRNA. Translation: AAN71999.1.
BT008401 mRNA. Translation: AAP37760.1.
PIRiB86295.
RefSeqiNP_173055.1. NM_101471.3.
UniGeneiAt.41906.

3D structure databases

ProteinModelPortaliQ9S9N1.
SMRiQ9S9N1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi23414. 8 interactors.
IntActiQ9S9N1. 3 interactors.
STRINGi3702.AT1G16030.1.

Proteomic databases

PaxDbiQ9S9N1.
PRIDEiQ9S9N1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G16030.1; AT1G16030.1; AT1G16030.
GeneIDi838174.
GrameneiAT1G16030.1; AT1G16030.1; AT1G16030.
KEGGiath:AT1G16030.

Organism-specific databases

TAIRiAT1G16030.

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
HOGENOMiHOG000228135.
InParanoidiQ9S9N1.
KOiK03283.
OMAiGGMPTDG.
OrthoDBiEOG093604KP.
PhylomeDBiQ9S9N1.

Enzyme and pathway databases

ReactomeiR-ATH-3371453. Regulation of HSF1-mediated heat shock response.
R-ATH-3371568. Attenuation phase.
R-ATH-3371571. HSF1-dependent transactivation.
R-ATH-6798695. Neutrophil degranulation.
R-ATH-72163. mRNA Splicing - Major Pathway.

Miscellaneous databases

PROiQ9S9N1.

Gene expression databases

GenevisibleiQ9S9N1. AT.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSP7E_ARATH
AccessioniPrimary (citable) accession number: Q9S9N1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.