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Protein

Aspartic proteinase-like protein 2

Gene

At1g65240

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei92By similarity1
Active sitei303By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl protease, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.A37.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartic proteinase-like protein 2 (EC:3.4.23.-)
Gene namesi
Ordered Locus Names:At1g65240
ORF Names:T23K8.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G65240.
TAIRilocus:2200365. AT1G65240.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000025944424 – 449Aspartic proteinase-like protein 2Add BLAST426
PropeptideiPRO_0000259445450 – 475Removed in mature formSequence analysisAdd BLAST26

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi124N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi222N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi425N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi446N-linked (GlcNAc...) asparagineSequence analysis1
Lipidationi449GPI-anchor amidated serineSequence analysis1

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

PaxDbiQ9S9K4.

Expressioni

Gene expression databases

ExpressionAtlasiQ9S9K4. baseline and differential.
GenevisibleiQ9S9K4. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G65240.1.

Structurei

3D structure databases

ProteinModelPortaliQ9S9K4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 422Peptidase A1PROSITE-ProRule annotationAdd BLAST349

Sequence similaritiesi

Belongs to the peptidase A1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1339. Eukaryota.
ENOG410XNV7. LUCA.
HOGENOMiHOG000006100.
InParanoidiQ9S9K4.
OMAiKTTPMVP.
OrthoDBiEOG09360BG9.
PhylomeDBiQ9S9K4.

Family and domain databases

CDDicd05476. pepsin_A_like_plant. 1 hit.
Gene3Di2.40.70.10. 2 hits.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR034161. Pepsin-like_plant.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom_sf.
IPR032799. TAXi_C.
IPR032861. TAXi_N.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiView protein in Pfam
PF14541. TAXi_C. 1 hit.
PF14543. TAXi_N. 1 hit.
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiView protein in PROSITE
PS51767. PEPTIDASE_A1. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9S9K4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELRRKLCIV VAVFVIVIEF ASANFVFKAQ HKFAGKKKNL EHFKSHDTRR
60 70 80 90 100
HSRMLASIDL PLGGDSRVDS VGLYFTKIKL GSPPKEYHVQ VDTGSDILWI
110 120 130 140 150
NCKPCPKCPT KTNLNFRLSL FDMNASSTSK KVGCDDDFCS FISQSDSCQP
160 170 180 190 200
ALGCSYHIVY ADESTSDGKF IRDMLTLEQV TGDLKTGPLG QEVVFGCGSD
210 220 230 240 250
QSGQLGNGDS AVDGVMGFGQ SNTSVLSQLA ATGDAKRVFS HCLDNVKGGG
260 270 280 290 300
IFAVGVVDSP KVKTTPMVPN QMHYNVMLMG MDVDGTSLDL PRSIVRNGGT
310 320 330 340 350
IVDSGTTLAY FPKVLYDSLI ETILARQPVK LHIVEETFQC FSFSTNVDEA
360 370 380 390 400
FPPVSFEFED SVKLTVYPHD YLFTLEEELY CFGWQAGGLT TDERSEVILL
410 420 430 440 450
GDLVLSNKLV VYDLDNEVIG WADHNCSSSI KIKDGSGGVY SVGADNLSSA
460 470
PRLLMITKLL TILSPLIVMA FTSLA
Length:475
Mass (Da):51,828
Last modified:October 31, 2006 - v2
Checksum:i1DD9C1A5EF147BA0
GO

Sequence cautioni

The sequence AAD26876 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007230 Genomic DNA. Translation: AAD26876.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34347.1.
PIRiE96676.
RefSeqiNP_176703.1. NM_105197.3.
UniGeneiAt.11165.
At.35907.

Genome annotation databases

EnsemblPlantsiAT1G65240.1; AT1G65240.1; AT1G65240.
GeneIDi842831.
GrameneiAT1G65240.1; AT1G65240.1; AT1G65240.
KEGGiath:AT1G65240.

Similar proteinsi

Entry informationi

Entry nameiASPL2_ARATH
AccessioniPrimary (citable) accession number: Q9S9K4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: March 28, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome