Q9S8T0 (LECB4_ARTIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Agglutinin beta-4 chain Alternative name(s): Jacalin beta-4 chain
Organism	Artocarpus integer (Jack fruit) (Artocarpus integrifolia)
Taxonomic identifier	3490 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › fabids › Rosales › Moraceae › Artocarpus

Protein attributes

Sequence length	20 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum By similarity. UniProtKB P18673
Subunit structure	Tetramer of four alpha chains associated with two or four beta chains By similarity. UniProtKB P18673
Sequence similarities	Belongs to the jacalin lectin family.

Ontologies

Keywords
Ligand	IgA-binding protein Lectin
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Molecular_function	IgA binding Inferred from sequence or structural similarity. Source: UniProtKB carbohydrate binding Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – ›20

›20

Agglutinin beta-4 chain

PRO_0000072799

Experimental info

Non-terminal residue

20

1

Secondary structure

1

.

.

.

20

Helix Strand Turn

Details...

Beta strand

10 – 16

7

Sequences

	Sequence		Length	Mass (Da)
	Q9S8T0 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 8D5AE975F4D0E212	FASTA	20	2,071
	10 20 NEQSGISQTV IVGPWGAQVT

References

[1]	"The alpha- and beta-subunits of the jacalins are cleavage products from a 17-kDa precursor." Ngoc L.D., Brillard M., Hoebeke J. Biochim. Biophys. Acta 1156:219-222(1993) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

PIR

S29636.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4AK4	X-ray	1.65	B/D/F/H/J/L/N/P	1-19	[»]
4AKB	X-ray	1.95	B/D/F/H	1-19	[»]
4AKC	X-ray	2.30	B/D/F/H	1-19	[»]

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

ProtoNet

Search...

Entry information

Entry name

LECB4_ARTIN

Accession

Primary (citable) accession number: Q9S8T0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 7, 2006
Last sequence update:	May 1, 2000
Last modified:	May 29, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program