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Q9S8T0 (LECB4_ARTIN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Agglutinin beta-4 chain
Alternative name(s):
Jacalin beta-4 chain
OrganismArtocarpus integer (Jack fruit) (Artocarpus integrifolia)
Taxonomic identifier3490 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesMoraceaeArtocarpus

Protein attributes

Sequence length20 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum By similarity. UniProtKB P18673

Subunit structure

Tetramer of four alpha chains associated with two or four beta chains By similarity. UniProtKB P18673

Sequence similarities

Belongs to the jacalin lectin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›20›20Agglutinin beta-4 chain
PRO_0000072799

Experimental info

Non-terminal residue201

Secondary structure

... 20
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9S8T0 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 8D5AE975F4D0E212

FASTA202,071
        10         20 
NEQSGISQTV IVGPWGAQVT 

« Hide

References

[1]"The alpha- and beta-subunits of the jacalins are cleavage products from a 17-kDa precursor."
Ngoc L.D., Brillard M., Hoebeke J.
Biochim. Biophys. Acta 1156:219-222(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

PIRS29636.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4AK4X-ray1.65B/D/F/H/J/L/N/P1-19[»]
4AKBX-ray1.95B/D/F/H1-19[»]
4AKCX-ray2.30B/D/F/H1-19[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameLECB4_ARTIN
AccessionPrimary (citable) accession number: Q9S8T0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 7, 2006
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references