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Q9S8T0

- LECB4_ARTIN

UniProt

Q9S8T0 - LECB4_ARTIN

Protein

Agglutinin beta-4 chain

Gene
N/A
Organism
Artocarpus integer (Jack fruit) (Artocarpus integrifolia)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum By similarity.By similarity

    GO - Molecular functioni

    1. carbohydrate binding Source: UniProtKB
    2. IgA binding Source: UniProtKB

    Keywords - Ligandi

    IgA-binding protein, Lectin

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Agglutinin beta-4 chain
    Alternative name(s):
    Jacalin beta-4 chain
    OrganismiArtocarpus integer (Jack fruit) (Artocarpus integrifolia)
    Taxonomic identifieri3490 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesMoraceaeArtocarpus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›20›20Agglutinin beta-4 chainPRO_0000072799Add
    BLAST

    Interactioni

    Subunit structurei

    Tetramer of four alpha chains associated with two or four beta chains.By similarity

    Structurei

    Secondary structure

    1
    20
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi10 – 167

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4AK4X-ray1.65B/D/F/H/J/L/N/P1-19[»]
    4AKBX-ray1.95B/D/F/H1-19[»]
    4AKCX-ray2.30B/D/F/H1-19[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the jacalin lectin family.Sequence Analysis

    Sequencei

    Sequence statusi: Fragment.

    Q9S8T0-1 [UniParc]FASTAAdd to Basket

    « Hide

    NEQSGISQTV IVGPWGAQVT                                    20
    Length:20
    Mass (Da):2,071
    Last modified:May 1, 2000 - v1
    Checksum:i8D5AE975F4D0E212
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei20 – 2011 Publication

    Sequence databases

    PIRiS29636.

    Cross-referencesi

    Sequence databases

    PIRi S29636.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4AK4 X-ray 1.65 B/D/F/H/J/L/N/P 1-19 [» ]
    4AKB X-ray 1.95 B/D/F/H 1-19 [» ]
    4AKC X-ray 2.30 B/D/F/H 1-19 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The alpha- and beta-subunits of the jacalins are cleavage products from a 17-kDa precursor."
      Ngoc L.D., Brillard M., Hoebeke J.
      Biochim. Biophys. Acta 1156:219-222(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiLECB4_ARTIN
    AccessioniPrimary (citable) accession number: Q9S8T0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 7, 2006
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3