ID   SCC11_ARATH             Reviewed;         627 AA.
AC   Q9S7T7; Q3E9L1; Q9SQI1;
DT   09-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2003, sequence version 2.
DT   16-JUN-2009, entry version 51.
DE   RecName: Full=Sister chromatid cohesion 1 protein 1;
DE   AltName: Full=SCC1 homolog 1;
DE   AltName: Full=Protein DETERMINATE INFERTILE 1;
GN   Name=SYN1; Synonyms=DIF1; OrderedLocusNames=At5g05490;
GN   ORFNames=MOP10.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), AND ALTERNATIVE
RP   PROMOTER USAGE.
RC   STRAIN=cv. Wassilewskija;
RX   MEDLINE=99172056; PubMed=10072401; DOI=10.1105/tpc.11.3.417;
RA   Bai X., Peirson B.N., Dong F., Xue C., Makaroff C.A.;
RT   "Isolation and characterization of SYN1, a RAD21-like gene essential
RT   for meiosis in Arabidopsis.";
RL   Plant Cell 11:417-430(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC   STRAIN=cv. Landsberg erecta;
RX   MEDLINE=99435885; PubMed=10504568;
RX   DOI=10.1046/j.1365-313X.1999.00548.x;
RA   Bhatt A.M., Lister C., Page T., Fransz P.F., Findlay K., Jones G.H.,
RA   Dickinson H.G., Dean C.;
RT   "The DIF1 gene of Arabidopsis is required for meiotic chromosome
RT   segregation and belongs to the REC8/RAD21 cohesin gene family.";
RL   Plant J. 19:463-472(1999).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   MEDLINE=97471969; PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA   Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA   Miyajima N., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT   features of the 1.6 Mb regions covered by twenty physically assigned
RT   P1 clones.";
RL   DNA Res. 4:215-230(1997).
CC   -!- FUNCTION: Involved in chromosome condensation, pairing and
CC       segregation during meiosis. Responsible for cohesion between
CC       replicated sister chromatids.
CC   -!- SUBUNIT: Component of the cohesin complex (By similarity).
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative promoter usage; Named isoforms=2;
CC       Name=2;
CC         IsoId=Q9S7T7-1; Sequence=Displayed;
CC       Name=1;
CC         IsoId=Q9S7T7-2; Sequence=VSP_007492;
CC   -!- TISSUE SPECIFICITY: Isoform 2 is expressed at low levels in buds,
CC       leaves and roots, whereas expression of isoform 1 is confined to
CC       buds.
CC   -!- SIMILARITY: Belongs to the rad21 family.
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DR   EMBL; AF080620; AAF08982.1; -; mRNA.
DR   EMBL; AF080619; AAF08981.1; -; mRNA.
DR   EMBL; AJ238306; CAB64643.1; -; mRNA.
DR   EMBL; AB005241; BAB11538.1; -; Genomic_DNA.
DR   IPI; IPI00517990; -.
DR   IPI; IPI00540220; -.
DR   PIR; T52571; T52571.
DR   RefSeq; NP_850773.1; -.
DR   UniGene; At.690; -.
DR   GeneID; 830432; -.
DR   GenomeReviews; BA000015_GR; AT5G05490.
DR   NMPDR; fig|3702.1.peg.22655; -.
DR   GeneFarm; 1768; -.
DR   TAIR; At5g05490; -.
DR   OMA; Q9S7T7; ICEEILN.
DR   ArrayExpress; Q9S7T7; -.
DR   GO; GO:0000228; C:nuclear chromosome; IEA:InterPro.
DR   GO; GO:0051455; P:attachment of spindle microtubules to kinet...; IMP:TAIR.
DR   GO; GO:0006325; P:establishment or maintenance of chromatin a...; IMP:TAIR.
DR   GO; GO:0010032; P:meiotic chromosome condensation; IMP:TAIR.
DR   GO; GO:0051754; P:meiotic sister chromatid cohesion, centromeric; IMP:TAIR.
DR   InterPro; IPR006909; Rad21/Rec8_C.
DR   InterPro; IPR006910; Rad21_Rec8_N.
DR   Pfam; PF04824; Rad21_Rec8; 1.
DR   Pfam; PF04825; Rad21_Rec8_N; 1.
PE   2: Evidence at transcript level;
KW   Alternative promoter usage; Cell cycle; Chromosome partition;
KW   Complete proteome; Meiosis; Nucleus.
FT   CHAIN         1    627       Sister chromatid cohesion 1 protein 1.
FT                                /FTId=PRO_0000097875.
FT   VAR_SEQ       1     16       MLRLESLIVTVWGPAT -> MFYSHQ (in isoform
FT                                1).
FT                                /FTId=VSP_007492.
SQ   SEQUENCE   627 AA;  71228 MW;  05D815E914233650 CRC64;
     MLRLESLIVT VWGPATLLAR KAPLGQIWMA ATLHAKINRK KLDKLDIIQI CEEILNPSVP
     MALRLSGILM GGVVIVYERK VKLLFDDVNR FLVEINGAWR TKSVPDPTLL PKGKTHARKE
     AVTLPENEEA DFGDFEQTRN VPKFGNYMDF QQTFISMRLD ESHVNNNPEP EDLGQQFHQA
     DAENITLFEY HGSFQTNNET YDRFERFDIE GDDETQMNSN PREGAEIPTT LIPSPPRHHD
     IPEGVNPTSP QRQEQQENRR DGFAEQMEEQ NIPDKEEHDR PQPAKKRARK TATSAMDYEQ
     TIIAGHVYQS WLQDTSDILC RGEKRKVRGT IRPDMESFKR ANMPPTQLFE KDSSYPPQLY
     QLWSKNTQVL QTSSSESRHP DLRAEQSPGF VQERMHNHHQ TDHHERSDTS SQNLDSPAEI
     LRTVRTGKGA SVESMMAGSR ASPETINRQA ADINVTPFYS GDDVRSMPST PSARGAASIN
     NIEISSKSRM PNRKRPNSSP RRGLEPVAEE RPWEHREYEF EFSMLPEKRF TADKEILFET
     ASTQTQKPVC NQSDEMITDS IKSHLKTHFE TPGAPQVESL NKLAVGMDRN AAAKLFFQSC
     VLATRGVIKV NQAEPYGDIL IARGPNM
//