ID   Q9S7M5_MALDO            Unreviewed;       159 AA.
AC   Q9S7M5;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2000, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   SubName: Full=Allergen Mal d 1.02 {ECO:0000313|EMBL:AAX18289.1, ECO:0000313|EMBL:AEF38452.1};
DE   SubName: Full=Major allergen mal d 1 {ECO:0000313|EMBL:AAD26559.1};
DE   SubName: Full=Mal d 1-like {ECO:0000313|EMBL:AAS00042.1};
DE   SubName: Full=Mal d 1.01 {ECO:0000313|EMBL:AEE38279.1};
DE   SubName: Full=Mal d 1.0201 {ECO:0000313|EMBL:AAX20918.1};
DE   SubName: Full=Putative Mal d 1.02 isoallergen {ECO:0000313|EMBL:CBL94141.1};
GN   Name=MALD1 {ECO:0000313|EMBL:AAD26559.1};
GN   Synonyms=Mal d 1.01 {ECO:0000313|EMBL:AEE38279.1}, Mal d 1.02
GN   {ECO:0000313|EMBL:AAX18289.1}, mal d 1.02
GN   {ECO:0000313|EMBL:AAX20925.1};
GN   ORFNames=DVH24_025444 {ECO:0000313|EMBL:RXH71943.1};
OS   Malus domestica (Apple) (Pyrus malus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Malus.
OX   NCBI_TaxID=3750 {ECO:0000313|EMBL:AAD26559.1};
RN   [1] {ECO:0000313|EMBL:AAD26559.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Gloster {ECO:0000313|EMBL:AAD26557.1}, Golden Delicious
RC   {ECO:0000313|EMBL:AAD26556.1}, Granny Smith
RC   {ECO:0000313|EMBL:AAD26545.1}, Idared {ECO:0000313|EMBL:AAD26549.1},
RC   and Royal Gala {ECO:0000313|EMBL:AAD26559.1};
RA   Son D.Y., Haustein D., Vieths S.;
RT   "Cloning and characterization of isoforms of the major apple allergen, Mal
RT   d 1, derived from different apple strains.";
RL   Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAS00042.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Beuning L.L., Bowen J.H., Persson H.A., Barraclough D., Bulley S.,
RA   MacRae E.A.;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAS00042.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15604687; DOI=10.1007/s11103-004-0904-9;
RA   Beuning L., Bowen J., Persson H., Barraclough D., Bulley S., Macrae E.;
RT   "Characterisation of Mal d 1-related genes in Malus.";
RL   Plant Mol. Biol. 55:369-388(2004).
RN   [4] {ECO:0000313|EMBL:AAX20918.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Young leaves {ECO:0000313|EMBL:AAX20918.1};
RA   Gao Z.S., Matos C., Van de Weg W.E., Gilissen L.J.W.J.;
RT   "Allelic diversity of seven intron-containing Mal d 1 (PR-10) genes among
RT   eight apple cultivars.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:AAX18289.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Young leaves {ECO:0000313|EMBL:AAX18289.1};
RX   PubMed=15883791; DOI=10.1007/s00122-005-2018-4;
RA   Gao Z.S., van de Weg W.E., Schaart J.G., Schouten H.J., Tran D.H.,
RA   Kodde L.P., van der Meer I.M., van der Geest A.H., Kodde J.,
RA   Breiteneder H., Hoffmann-Sommergruber K., Bosch D., Gilissen L.J.;
RT   "Genomic cloning and linkage mapping of the Mal d 1 (PR-10) gene family in
RT   apple (Malus domestica).";
RL   Theor. Appl. Genet. 111:171-183(2005).
RN   [6] {ECO:0000313|EMBL:CBL94141.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Pagliarani G., Paris R., Arens P., Tartarini S., Peters S., van de Weg E.;
RT   "Genomic organization of the Mal d 1 gene cluster on apple (Malus x
RT   domestica) linkage group 16.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|EMBL:AEE38279.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Bokszczanin K.L., Przybyla A., Filipecki M.;
RT   "Allelic diversity of Mal d 1 (PR-10) genes in apple cultivars.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [8] {ECO:0000313|EMBL:RXH71943.1, ECO:0000313|Proteomes:UP000290289}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. HFTH1 {ECO:0000313|Proteomes:UP000290289};
RC   TISSUE=Young leaf {ECO:0000313|EMBL:RXH71943.1};
RA   Hu J.;
RT   "A high-quality apple genome assembly.";
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the BetVI family.
CC       {ECO:0000256|ARBA:ARBA00009744, ECO:0000256|RuleBase:RU000409}.
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DR   EMBL; AF124822; AAD26545.1; -; mRNA.
DR   EMBL; AF124826; AAD26549.1; -; mRNA.
DR   EMBL; AF124827; AAD26550.1; -; mRNA.
DR   EMBL; AF124828; AAD26551.1; -; mRNA.
DR   EMBL; AF124833; AAD26556.1; -; mRNA.
DR   EMBL; AF124834; AAD26557.1; -; mRNA.
DR   EMBL; AF124836; AAD26559.1; -; mRNA.
DR   EMBL; AY428578; AAS00042.1; -; mRNA.
DR   EMBL; AY789239; AAX18289.1; -; Genomic_DNA.
DR   EMBL; AY789240; AAX18290.1; -; Genomic_DNA.
DR   EMBL; AY789241; AAX18291.1; -; Genomic_DNA.
DR   EMBL; AY827646; AAX20918.1; -; Genomic_DNA.
DR   EMBL; AY827647; AAX20919.1; -; Genomic_DNA.
DR   EMBL; AY827648; AAX20920.1; -; Genomic_DNA.
DR   EMBL; AY827649; AAX20921.1; -; Genomic_DNA.
DR   EMBL; AY827650; AAX20922.1; -; Genomic_DNA.
DR   EMBL; AY827651; AAX20923.1; -; Genomic_DNA.
DR   EMBL; AY827652; AAX20924.1; -; Genomic_DNA.
DR   EMBL; AY827653; AAX20925.1; -; Genomic_DNA.
DR   EMBL; AY827654; AAX20926.1; -; Genomic_DNA.
DR   EMBL; AY827655; AAX20927.1; -; Genomic_DNA.
DR   EMBL; AY827656; AAX20928.1; -; Genomic_DNA.
DR   EMBL; AY827657; AAX20929.1; -; Genomic_DNA.
DR   EMBL; AY827658; AAX20930.1; -; Genomic_DNA.
DR   EMBL; AY827659; AAX20931.1; -; Genomic_DNA.
DR   EMBL; JF682504; AEE38279.1; -; Genomic_DNA.
DR   EMBL; JF507716; AEF38452.1; -; Genomic_DNA.
DR   EMBL; JF507719; AEF38455.1; -; Genomic_DNA.
DR   EMBL; JF507723; AEF38459.1; -; Genomic_DNA.
DR   EMBL; FN823234; CBL94141.1; -; Genomic_DNA.
DR   EMBL; RDQH01000342; RXH71943.1; -; Genomic_DNA.
DR   RefSeq; NP_001281292.1; NM_001294363.1.
DR   AlphaFoldDB; Q9S7M5; -.
DR   SMR; Q9S7M5; -.
DR   STRING; 3750.Q9S7M5; -.
DR   Allergome; 1457; Mal d 1.0202.
DR   Allergome; 464; Mal d 1.
DR   EnsemblPlants; mRNA:MD16G0142600; mRNA:MD16G0142600; MD16G0142600.
DR   GeneID; 103425638; -.
DR   Gramene; mRNA:MD16G0142600; mRNA:MD16G0142600; MD16G0142600.
DR   KEGG; mdm:103425638; -.
DR   OrthoDB; 1201344at2759; -.
DR   Proteomes; UP000290289; Chromosome 16.
DR   GO; GO:0010427; F:abscisic acid binding; IEA:InterPro.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR   CDD; cd07816; Bet_v1-like; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR000916; Bet_v_I/MLP.
DR   InterPro; IPR024949; Bet_v_I_allergen.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   PANTHER; PTHR31213:SF55; CLASS-10 PATHOGENESIS-RELATED PROTEIN 1; 1.
DR   PANTHER; PTHR31213; OS03G0300400 PROTEIN-RELATED; 1.
DR   Pfam; PF00407; Bet_v_1; 1.
DR   PRINTS; PR00634; BETALLERGEN.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   PROSITE; PS00451; PATHOGENESIS_BETVI; 1.
PE   2: Evidence at transcript level;
KW   Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW   ECO:0000256|RuleBase:RU000409};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821,
KW   ECO:0000256|RuleBase:RU000409};
KW   Reference proteome {ECO:0000313|Proteomes:UP000290289}.
FT   DOMAIN          1..151
FT                   /note="Bet v I/Major latex protein"
FT                   /evidence="ECO:0000259|Pfam:PF00407"
SQ   SEQUENCE   159 AA;  17539 MW;  7332100D2C614446 CRC64;
     MGVYTFENEY TSEIPPPRLF KAFVLDADNL IPKIAPQAIK HAEILEGDGG PGTIKKITFG
     EGSQYGYVKH KIDSVDEANY SYAYTLIEGD ALTDTIEKVS YETKLVASGS GSIIKSISHY
     HTKGDVEIKE EHVKAGKEKA HGLFKLIESY LKGHPDAYN
//