Reviewed, UniProtKB/Swiss-Prot Q9S6S3 (GALT_LACLM)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	llmg_2234

Organism

Lactococcus lactis subsp. cremoris (strain MG1363) [Complete proteome] [HAMAP]

Taxonomic identifier

416870 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	493 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 493	493	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169909

Sequences

	Sequence		Length	Mass (Da)
	Q9S6S3-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 05BFA76B3F6E5022	FASTA	493	56,260
	10 20 30 40 50 60 MSIYQSIQDF ISLALQNGTI EPLDELYHRN QLLHFLGLND WAEVDKEVHE TNSLILMDQL 70 80 90 100 110 120 LAIANENNVI AKGQDEFYEA ALMNFMTPRP SKINHDFWEK YQASPDDATQ YFYELAQQVN 130 140 150 160 170 180 QVKTRDIARN IAFSHLTKYG KLEITINLSK PEKDPKAIAA AKLVKASSYP ACQLCLENEG 190 200 210 220 230 240 FYGLGNKPAR SNHRIIQVSI NGEDWGFQYS PYAYFNEHSI LLNAKHQPME INKRAFDNLL 250 260 270 280 290 300 GFLDKFPNYM IGSNADLPIV GGSILTHDHY QAGRHDFPMA KAELRETIEL AHFPEVSCGI 310 320 330 340 350 360 VNWPMSVLRL ASENQVELSK AADDFLKKWQ VYSDESLQIK AKSTDGTPHH TITPIARIRD 370 380 390 400 410 420 GKYELDLVLR DNNTNEKYPD GIFHPHPALH HIKKENIGLI EVMGLAILPA RLGTELLEVE 430 440 450 460 470 480 KYLLNQDNQM DEIHKAWAEQ LKNEEHFTRE TVHATVQGAV GEVFEEVLKD AGVFKDTQEG 490 HEGFRKFIDF VNQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization, expression and mutations of the Lactococcus lactis galAMKTE genes involved in galactose utilization via the Leloir pathway." Grossiord B.P., Luesink E.J., Vaughan E.E., Kuipers O.P., De Vos W.M. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363." Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J. J. Bacteriol. 189:3256-3270(2007) [PubMed: 17307855] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ011653 Genomic DNA. Translation: CAB44217.1. AM406671 Genomic DNA. Translation: CAL98801.1.
RefSeq	YP_001033484.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9S6S3.
Genome annotation databases
GeneID	4799060.
GenomeReviews	Gene locus llmg_2234 in contig AM406671_GR.
KEGG	llm:llmg_2234.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4468.
HOGENOM	HBG337915.
OMA	EHYQGGR.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. galT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_LACLM

Accession

Primary (citable) accession number: Q9S6S3
Secondary accession number(s): A2RNB3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	May 1, 2000
Last modified:	February 9, 2010
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)