Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycosyltransferase TibC

Gene

tibC

Organism
Escherichia coli O78:H11 (strain H10407 / ETEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Glycosylates the TibA adhesin.1 Publication

GO - Molecular functioni

  • transferase activity, transferring glycosyl groups Source: CACAO

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glycosyltransferase TibC (EC:2.4.-.-)
Gene namesi
Name:tibC
Ordered Locus Names:ETEC_2140
OrganismiEscherichia coli O78:H11 (strain H10407 / ETEC)
Taxonomic identifieri316401 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000006877 Componenti: Chromosome

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi90E → K: No effect. 1 Publication1
Mutagenesisi348L → P: No effect. 1 Publication1
Mutagenesisi358C → R: Loss of glycosyltransferase activity. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000763541 – 406Glycosyltransferase TibCAdd BLAST406

Proteomic databases

PRIDEiQ9S4K6.

Structurei

Secondary structure

1406
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi17 – 19Combined sources3
Helixi21 – 23Combined sources3
Beta strandi25 – 28Combined sources4
Beta strandi31 – 36Combined sources6
Beta strandi41 – 47Combined sources7
Turni48 – 50Combined sources3
Beta strandi53 – 65Combined sources13
Beta strandi74 – 79Combined sources6
Beta strandi81 – 85Combined sources5
Beta strandi87 – 91Combined sources5
Beta strandi98 – 102Combined sources5
Helixi108 – 125Combined sources18
Beta strandi128 – 132Combined sources5
Helixi135 – 141Combined sources7
Helixi142 – 144Combined sources3
Beta strandi148 – 151Combined sources4
Beta strandi162 – 166Combined sources5
Beta strandi176 – 180Combined sources5
Helixi182 – 185Combined sources4
Turni187 – 189Combined sources3
Helixi190 – 195Combined sources6
Beta strandi218 – 221Combined sources4
Helixi228 – 230Combined sources3
Helixi237 – 247Combined sources11
Beta strandi251 – 254Combined sources4
Beta strandi259 – 263Combined sources5
Beta strandi266 – 269Combined sources4
Helixi283 – 291Combined sources9
Beta strandi294 – 298Combined sources5
Helixi303 – 309Combined sources7
Beta strandi314 – 317Combined sources4
Beta strandi319 – 321Combined sources3
Helixi323 – 325Combined sources3
Helixi342 – 344Combined sources3
Turni359 – 363Combined sources5
Turni365 – 368Combined sources4
Helixi369 – 372Combined sources4
Helixi376 – 390Combined sources15
Turni395 – 397Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4RAPX-ray2.88A/B/C/D/E/F/G/H/I/J/K/L1-406[»]
ProteinModelPortaliQ9S4K6.
SMRiQ9S4K6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

OMAiEFYTPWR.

Family and domain databases

InterProiIPR030929. Aah/TibC.
IPR002201. Glyco_trans_9.
[Graphical view]
PfamiPF01075. Glyco_transf_9. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04414. hepto_Aah_TibC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9S4K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLKNTFFI TPPDTPTQAG PENIFYDFND GARVLLPEGK WHVRLLDADS
60 70 80 90 100
ENILFCCDVD KGWVTSSKKY FVRFRIQVFR QGEETPLLDE TLKLKDRPVL
110 120 130 140 150
ISFPTGTLGD LLGWFPYAER FQSLHKCRLE CTMSQDIIDL LAPQYPQIQF
160 170 180 190 200
STPDKPRTVA PYATYRVGLY FGGDTNNQPV DFRKVGFHRS AGYILGVDPR
210 220 230 240 250
EAPVRLDLSA PRVIQEPYVC IATQSTCQAK YWNNGTGWSE VIAHLKSLGY
260 270 280 290 300
RVMCIDRDAH YGQGFVWNHI PWGAEDFTGK LPLQERVNLL RHASFFIGLP
310 320 330 340 350
SGLSWLAWAT RIPVVLISGF SLPNSEFYTP WRVFNSHGCY GCWDDTSLNF
360 370 380 390 400
DHHDFLWCPR HKNTDRQFEC TRLITGAQVN GVINKLHRSL TEQGVEATLK

KGVSNE
Length:406
Mass (Da):46,325
Last modified:May 1, 2000 - v1
Checksum:i3FDDEA5C9D2FBDD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF131891 Genomic DNA. Translation: AAD46996.1.
FN649414 Genomic DNA. Translation: CBJ01642.1.
RefSeqiWP_000105682.1. NC_017633.1.

Genome annotation databases

EnsemblBacteriaiCBJ01642; CBJ01642; ETEC_2140.
KEGGielh:ETEC_2140.
PATRICi42960170. VBIEscCol136115_2452.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF131891 Genomic DNA. Translation: AAD46996.1.
FN649414 Genomic DNA. Translation: CBJ01642.1.
RefSeqiWP_000105682.1. NC_017633.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4RAPX-ray2.88A/B/C/D/E/F/G/H/I/J/K/L1-406[»]
ProteinModelPortaliQ9S4K6.
SMRiQ9S4K6.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ9S4K6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBJ01642; CBJ01642; ETEC_2140.
KEGGielh:ETEC_2140.
PATRICi42960170. VBIEscCol136115_2452.

Phylogenomic databases

OMAiEFYTPWR.

Family and domain databases

InterProiIPR030929. Aah/TibC.
IPR002201. Glyco_trans_9.
[Graphical view]
PfamiPF01075. Glyco_transf_9. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04414. hepto_Aah_TibC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTIBC_ECOH1
AccessioniPrimary (citable) accession number: Q9S4K6
Secondary accession number(s): E3PBM2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: May 1, 2000
Last modified: November 2, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Able to functionally replace the autotransporter adhesin heptosyltransferase (AAH) of the AIDA system in fully restoring activity to the AIDA-I adhesin depending on the modification of AIDA with heptose residues.

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.