Sortase - Staphylococcus aureus

Contribute

Read comments (?) or add your own

Q9S446 (Q9S446_STAAU) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 44. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

text xml rdf/xml gff fasta

to top of page

Names·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

to top of page

Names·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Sortase EMBL AAD48437.1

Gene names

Name:

srtA EMBL AAD48437.1

Organism

Staphylococcus aureus EMBL AAD48437.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Calcium PDB 2KID Metal-binding PDB 2KID
Technical term	3D-structure PDB 2KID PDB 1T2W PDB 1T2O PDB 1IJA PDB 1T2P
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

1

Calcium PDB 2KID

Metal binding

1

Calcium PDB 2KID

Metal binding

1

Calcium PDB 2KID

Metal binding

1

Calcium; via carbonyl oxygen PDB 2KID

Metal binding

1

Calcium PDB 2KID

Sequences

Sequence

Length

Mass (Da)

Tools

Q9S446 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: DC3E65C51E145C7B
Show »

206

23,541

        10         20         30         40         50         60 
MKKWTNRLMT IAGVVLILVA AYLFAKPHID NYLHDKDKDE KIEQYDKNVK EQASKDKKQQ 

        70         80         90        100        110        120 
AKPQIPKDKS KVAGYIEIPD ADIKEPVYPG PATPEQLNRG VSFAEENESL DDQNISIAGH 

       130        140        150        160        170        180 
TFIDRPNYQF TNLKAAKKGS MVYFKVGNET RKYKMTSIRD VKPTDVGVLD EQKGKDKQLT 

       190        200 
LITCDDYNEK TGVWEKRKIF VATEVK

References

[1]	"Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall." Mazmanian S.K., Liu G., Ton-That H., Schneewind O. Science 285:760-763(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 8325-4 EMBL AAD48437.1.
[2]	"Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus." Ilangovan U., Ton-That H., Iwahara J., Schneewind O., Clubb R.T. Proc. Natl. Acad. Sci. U.S.A. 98:6056-6061(2001) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR OF 60-206.
[3]	"Crystal structures of Staphylococcus aureus sortase A and its substrate complex." Zong Y., Bice T.W., Ton-That H., Schneewind O., Narayana S.V. J. Biol. Chem. 279:31383-31389(2004) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 62-206.
[4]	"The structure of the Staphylococcus aureus sortase-substrate complex reveals how the universally conserved LPXTG sorting signal is recognized." Suree N., Liew C.K., Villareal V.A., Thieu W., Fadeev E.A., Clemens J.J., Jung M.E., Clubb R.T. J. Biol. Chem. 284:24465-24477(2009) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR OF 60-206 IN COMPLEX WITH CALCIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF162687 Genomic DNA. Translation: AAD48437.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1IJA	NMR	-	A	60-206	[»]
1T2O	X-ray	2.30	A/B/C	61-206	[»]
1T2P	X-ray	2.00	A/B/C	61-206	[»]
1T2W	X-ray	1.80	A/B/C	62-206	[»]
2KID	NMR	-	A	60-206	[»]

ProteinModelPortal

SMR

Q9S446. Positions 62-206.

ModBase

Protein family/group databases

MEROPS

Protocols and materials databases

StructuralBiologyKnowledgebase

Enzyme and pathway databases

BRENDA

3.4.22.B21. 95.

SABIO-RK

Family and domain databases

Gene3D

2.40.260.10. 1 hit.

InterPro

IPR005754. Sortase.
IPR023365. Sortase_dom.
[Graphical view]

Pfam

PF04203. Sortase. 1 hit.
[Graphical view]

SUPFAM

SSF63817. SSF63817. 1 hit.

TIGRFAMs

TIGR01076. sortase_fam. 1 hit.

ProtoNet

Other

BindingDB

ChEMBL

EvolutionaryTrace

Entry information

Entry name

Q9S446_STAAU

Accession

Primary (citable) accession number: Q9S446

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

to top of page

Names·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info