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Q9S427

- Q9S427_9GAMM

UniProt

Q9S427 - Q9S427_9GAMM

Protein
Submitted name:

Protein-tyrosine-phosphatase

Gene

PPI

Organism
Shewanella sp.
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi97 – 971Calcium 1Imported
    Metal bindingi97 – 971Zinc 1Imported
    Metal bindingi99 – 991Calcium 1; via tele nitrogenImported
    Metal bindingi99 – 991Zinc 1; via tele nitrogenImported
    Metal bindingi133 – 1331Calcium 1Imported
    Metal bindingi133 – 1331Calcium 2Imported
    Metal bindingi133 – 1331Zinc 1Imported
    Metal bindingi133 – 1331Zinc 2Imported
    Metal bindingi168 – 1681Calcium 2Imported
    Metal bindingi168 – 1681Zinc 2Imported
    Metal bindingi226 – 2261Calcium 2; via tele nitrogenImported
    Metal bindingi226 – 2261Zinc 2; via tele nitrogenImported
    Metal bindingi305 – 3051Calcium 2; via pros nitrogenImported
    Metal bindingi305 – 3051Zinc 2; via pros nitrogenImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    HydrolaseImported

    Keywords - Ligandi

    CalciumImported, Metal-bindingImported, ZincImported

    Protein family/group databases

    PptaseDBiP3D0411150.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein-tyrosine-phosphataseImported (EC:3.1.3.48Imported)
    Gene namesi
    Name:PPIImported
    OrganismiShewanella sp.Imported
    Taxonomic identifieri50422 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

    Pathology & Biotechi

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1V73X-ray1.82A22-361[»]
    2Z72X-ray1.10A22-361[»]
    2ZBMX-ray1.50A22-355[»]
    ProteinModelPortaliQ9S427.
    SMRiQ9S427. Positions 25-355.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9S427.

    Family & Domainsi

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9S427-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNKIYCLAVL SLTLLSPLAL ANTATEFDGP YVITPISGQS TAYWICDNRL    50
    KTTSIEKLQV NRPEHCGDLP ETKLSSEIKQ IMPDTYLGIK KVVALSDVHG 100
    QYDVLLTLLK KQKIIDSDGN WAFGEGHMVM TGDIFDRGHQ VNEVLWFMYQ 150
    LDQQARDAGG MVHLLMGNHE QMVLGGDLRY VHQRYDIATT LINRPYNKLY 200
    GADTEIGQWL RSKNTIIKIN DVLYMHGGIS SEWISRELTL DKANALYRAN 250
    VDASKKSLKA DDLLNFLFFG NGPTWYRGYF SETFTEAELD TILQHFNVNH 300
    IVVGHTSQER VLGLFHNKVI AVDSSIKVGK SGELLLLENN RLIRGLYDGT 350
    RETLQENSLN Q 361
    Length:361
    Mass (Da):40,815
    Last modified:May 1, 2000 - v1
    Checksum:iD44CF9FC13D08039
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF164202 Genomic DNA. Translation: AAD45611.1.
    PIRiJC7171.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF164202 Genomic DNA. Translation: AAD45611.1 .
    PIRi JC7171.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1V73 X-ray 1.82 A 22-361 [» ]
    2Z72 X-ray 1.10 A 22-361 [» ]
    2ZBM X-ray 1.50 A 22-355 [» ]
    ProteinModelPortali Q9S427.
    SMRi Q9S427. Positions 25-355.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    DrugBanki DB05260. Gallium nitrate.

    Protein family/group databases

    PptaseDBi P3D0411150.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q9S427.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of phosphatase I gene from a psychrophile, Shewanella sp., and some properties of the recombinant enzyme."
      Tsuruta H., Aizono Y.
      J. Biochem. 127:143-149(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Crystal structure of cold-active protein-tyrosine phosphatase from a psychrophile, Shewanella sp."
      Tsuruta H., Mikami B., Aizono Y.
      J. Biochem. 137:69-77(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) OF 22-361 IN COMPLEX WITH CALCIUM.
    3. "The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase."
      Tsuruta H., Mikami B., Yamamoto C., Yamagata H.
      FEBS J. 275:4317-4328(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.10 ANGSTROMS) OF 22-361 IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiQ9S427_9GAMM
    AccessioniPrimary (citable) accession number: Q9S427
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3