Q9S3Z4 (XYLA_STRCK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylose isomerase
EC=5.3.1.5

Gene names

Name:

xylA

Organism

Streptomyces corchorusii (Streptomyces chibaensis)

Taxonomic identifier

1903 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-xylose = D-xylulose. HAMAP-Rule MF_00455
Cofactor	Binds 2 magnesium ions per subunit By similarity.
Subunit structure	Homotetramer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the xylose isomerase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Pentose shunt Xylose metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
Gene Ontology (GO)
Biological_process	D-xylose metabolic process Inferred from electronic annotation. Source: HAMAP pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP xylose isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 388	388	Xylose isomerase HAMAP-Rule MF_00455		PRO_0000195797
Sites
	Active site	54	1	By similarity
	Active site	57	1	By similarity
	Metal binding	181	1	Magnesium 1 By similarity
	Metal binding	217	1	Magnesium 1 By similarity
	Metal binding	217	1	Magnesium 2 By similarity
	Metal binding	220	1	Magnesium 2 By similarity
	Metal binding	245	1	Magnesium 1 By similarity
	Metal binding	255	1	Magnesium 2 By similarity
	Metal binding	257	1	Magnesium 2 By similarity
	Metal binding	287	1	Magnesium 1 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9S3Z4 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 6AB17C6473EF52AC	FASTA	388	42,967
	10 20 30 40 50 60 MSYQPTPEDR FTFGLWTVGW QGRDPFGDAT RRALDPVETV QRLAELGAHG VTFHDDDLIP 70 80 90 100 110 120 FGSSDTERES HIKRFRQALD ATGMTVPMAT TNLFTHPVFK DGAFTANDRD VRRYALRKTI 130 140 150 160 170 180 RNIDLAAELG AKTYVAWGGR EGAESGAAKD VRSALDRMKE AFDLLGEYVT SQGYDLRFAI 190 200 210 220 230 240 EPKPNEPRGD ILLPTVGHAL AFIERLERPE LYGVNPEVGH EQMAGLNFPH GIAQALWAGK 250 260 270 280 290 300 LFHIDLNGQS GIKYDQDLRF GAGDLRSAFW LVDLLESAGY EGPRHFDFKP PRTEDLDGVW 310 320 330 340 350 360 ASAAGCMRNY LILKERAAAF RADPEVQAAL RASRLDQLAQ PTAADGLEDL LADRAAFEDF 370 380 DVEAAAARGM AFERLDQLAM DHLLGARG

References

[1]	"Streptomyces chibaensis J-59 xylA." Joo G.J., Shin J.H., Heo G.Y., Park H.D., Rhee I.K. Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: J-59.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF170068 Genomic DNA. Translation: AAD48850.1.
3D structure databases
ProteinModelPortal	Q9S3Z4.
SMR	Q9S3Z4. Positions 2-387.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.20.20.150. 1 hit.
HAMAP	MF_00455. Xylose_isom_A.
InterPro	IPR013022. Xyl_isomerase-like_TIM-brl. IPR013453. XylA_actinobac. IPR001998. Xylose_isomerase. [Graphical view]
Pfam	PF01261. AP_endonuc_2. 1 hit. [Graphical view]
PRINTS	PR00688. XYLOSISMRASE.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR02631. xylA_Arthro. 1 hit.
PROSITE	PS51415. XYLOSE_ISOMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLA_STRCK

Accession

Primary (citable) accession number: Q9S3Z4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	May 1, 2000
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program