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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Zymomonas mobilis subsp. pomaceae (strain ATCC 29192 / JCM 10191 / NBRC 13757 / NCIMB 11200 / NRRL B-4491)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciZMOB579138:GJDN-656-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:Zymop_0633
OrganismiZymomonas mobilis subsp. pomaceae (strain ATCC 29192 / JCM 10191 / NBRC 13757 / NCIMB 11200 / NRRL B-4491)
Taxonomic identifieri579138 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas
ProteomesiUP000000491 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 211211N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154396Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9S3U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

KOiK01817.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9S3U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVRTKICGI STPETLLAAV KNGASHIGFV FFEKSPRAVQ PEMASMLINR
60 70 80 90 100
IPDHIDKIGV LVDPDDNLLE RVVHAGLTGF QLHGHETPER VAFIRRTFPK
110 120 130 140 150
VKIWKALPIT RSQDLDQTLH YRGLVDRVLY DARTDGALPG GMGKRFDWRL
160 170 180 190 200
LKDYNHPMAW ALSGGLDADN IAQAVAITGA ELVDVSSGVE TAPGIKDMDK
210
IAQFLQAVRL L
Length:211
Mass (Da):23,262
Last modified:December 14, 2011 - v2
Checksum:i385307A59D1F856E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti10 – 101I → L in AAD51337 (Ref. 1) Curated
Sequence conflicti13 – 2614PETLL…NGASH → EETVETAVRYGADY in AAD51337 (Ref. 1) CuratedAdd
BLAST
Sequence conflicti38 – 458AVQPEMAS → SVTPEKAA in AAD51337 (Ref. 1) Curated
Sequence conflicti49 – 502NR → RQ in AAD51337 (Ref. 1) Curated
Sequence conflicti55 – 562ID → VQ in AAD51337 (Ref. 1) Curated
Sequence conflicti61 – 611L → F in AAD51337 (Ref. 1) Curated
Sequence conflicti66 – 661D → N in AAD51337 (Ref. 1) Curated
Sequence conflicti72 – 754VVHA → ALAS in AAD51337 (Ref. 1) Curated
Sequence conflicti88 – 881P → A in AAD51337 (Ref. 1) Curated
Sequence conflicti91 – 966VAFIRR → IASIRE in AAD51337 (Ref. 1) Curated
Sequence conflicti108 – 1114PITR → SIAN in AAD51337 (Ref. 1) Curated
Sequence conflicti116 – 1194DQTL → AQAP in AAD51337 (Ref. 1) Curated
Sequence conflicti125 – 1251V → A in AAD51337 (Ref. 1) Curated
Sequence conflicti128 – 1281V → L in AAD51337 (Ref. 1) Curated
Sequence conflicti137 – 1371A → V in AAD51337 (Ref. 1) Curated
Sequence conflicti144 – 1441K → R in AAD51337 (Ref. 1) Curated
Sequence conflicti153 – 1597DYNHPMA → EYKHPLP in AAD51337 (Ref. 1) Curated
Sequence conflicti169 – 1691D → H in AAD51337 (Ref. 1) Curated
Sequence conflicti185 – 1851V → I in AAD51337 (Ref. 1) Curated
Sequence conflicti192 – 1921A → S in AAD51337 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF173835 Genomic DNA. Translation: AAD51337.1.
CP002865 Genomic DNA. Translation: AEI37535.1.
RefSeqiWP_013933934.1. NC_015709.1.
YP_004661825.1. NC_015709.1.

Genome annotation databases

EnsemblBacteriaiAEI37535; AEI37535; Zymop_0633.
KEGGizmp:Zymop_0633.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF173835 Genomic DNA. Translation: AAD51337.1.
CP002865 Genomic DNA. Translation: AEI37535.1.
RefSeqiWP_013933934.1. NC_015709.1.
YP_004661825.1. NC_015709.1.

3D structure databases

ProteinModelPortaliQ9S3U4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEI37535; AEI37535; Zymop_0633.
KEGGizmp:Zymop_0633.

Phylogenomic databases

KOiK01817.

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.
BioCyciZMOB579138:GJDN-656-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Zymomonas trpFBA genes."
    Eddy C.K., Ingram L.O.
    Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 29192 / JCM 10191 / NBRC 13757 / NCIMB 11200 / NRRL B-4491.
  2. "Genome sequence of the ethanol-producing Zymomonas mobilis subsp. pomaceae lectotype strain ATCC 29192."
    Kouvelis V.N., Davenport K.W., Brettin T.S., Bruce D., Detter C., Han C.S., Nolan M., Tapia R., Damoulaki A., Kyrpides N.C., Typas M.A., Pappas K.M.
    J. Bacteriol. 193:5049-5050(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29192 / JCM 10191 / NBRC 13757 / NCIMB 11200 / NRRL B-4491.

Entry informationi

Entry nameiTRPF_ZYMMT
AccessioniPrimary (citable) accession number: Q9S3U4
Secondary accession number(s): F8ERS7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: December 14, 2011
Last modified: May 27, 2015
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.