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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Pseudomonas fluorescens
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo_1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo_2), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo_1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo_1), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo_2), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Malate dehydrogenase (quinone) (BFW87_16160), Probable malate:quinone oxidoreductase (mqo_2), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
OrganismiPseudomonas fluorescens
Taxonomic identifieri294 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001287311 – 505Probable malate:quinone oxidoreductaseAdd BLAST505

Structurei

3D structure databases

ProteinModelPortaliQ9S3Q5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9S3Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHNEAVDVV HVVLVGAGIM SATLAVLLKE LDPAISLEVV ELMDSGAAES
60 70 80 90 100
SNPWNNAGTG HAGLCELNYT PQAADGNVDI KKAVHINTQF EVSKQFWTYL
110 120 130 140 150
TRKGTFGSSK SFIAPVPHLS FVQGEKGVSF LKKRFELMHQ HHAFADMEYT
160 170 180 190 200
EDKARMAEWM PLMMPGRPAD EVIAATRVMN GTDVNFGALT NQLLKHLTSA
210 220 230 240 250
PDTQVKYCKR VTGLKRNGSG WTVSIKDVNS GSSRDVDAKF VFLGAAGAAL
260 270 280 290 300
PLLQASGIEE SKGFGGFPVS GQWLRCDNPE VVKHHQAKVY SQAAVGSPPM
310 320 330 340 350
SVPHLTPVWS MARNPCLFGP YAGFTTKFLK HGSIMDLPLS VRAGNIGPML
360 370 380 390 400
AVARDNMDLT KYLISEVMQS MEQRLESLRR FYPEAKAEDW RLEVAGQRVQ
410 420 430 440 450
IIKKDPKKGG VLQFGTELVA AKDGSLAALL GASPGASVTV SIMLELIERC
460 470 480 490 500
FPDKAKGEWA TKLAEIFPAR EKVLETDAAL YRKINAQNNI ALELVEESSE

TQSYA
Length:505
Mass (Da):55,006
Last modified:May 1, 2000 - v1
Checksum:i28DB99B265EE8179
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF176206 Genomic DNA. Translation: AAD51981.1.

Similar proteinsi

Entry informationi

Entry nameiMQO_PSEFL
AccessioniPrimary (citable) accession number: Q9S3Q5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: May 1, 2000
Last modified: October 25, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families