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Q9S1A6

- Q9S1A6_SHIBL

UniProt

Q9S1A6 - Q9S1A6_SHIBL

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Protein

Acid phosphatase

Gene

pho

Organism
Shimwellia blattae (Escherichia blattae)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei168 – 1681Proton donor/acceptorImported
Sitei201 – 2011Transition state stabilizerImported
Active sitei207 – 2071NucleophileImported
Sitei211 – 2111Important for catalytic activityImported

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Acid phosphataseUniRule annotation (EC:3.1.3.2UniRule annotation)
Gene namesi
Name:phoImported
OrganismiShimwellia blattae (Escherichia blattae)Imported
Taxonomic identifieri563 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShimwellia

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
  2. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1D2TX-ray1.90A19-249[»]
1EOIX-ray2.40A/B/C19-249[»]
1IW8X-ray2.50A/B/C/D/E/F19-249[»]
ProteinModelPortaliQ9S1A6.
SMRiQ9S1A6. Positions 25-246.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9S1A6.

Family & Domainsi

Sequence similaritiesi

Belongs to the class A bacterial acid phosphatase family.UniRule annotation

Phylogenomic databases

KOiK09474.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9S1A6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKRVLAVCF AALFSSQALA LVATGNDTTT KPDLYYLKNS EAINSLALLP
60 70 80 90 100
PPPAVGSIAF LNDQAMYEQG RLLRNTERGK LAAEDANLSS GGVANAFSGA
110 120 130 140 150
FGSPITEKDA PALHKLLTNM IEDAGDLATR SAKDHYMRIR PFAFYGVSTC
160 170 180 190 200
NTTEQDKLSK NGSYPSGHTS IGWATALVLA EINPQRQNEI LKRGYELGQS
210 220 230 240
RVICGYHWQS DVDAARVVGS AVVATLHTNP AFQQQLQKAK AEFAQHQKK
Length:249
Mass (Da):26,957
Last modified:May 1, 2000 - v1
Checksum:i7AEAE6CB61FC0CA3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB020481 Genomic DNA. Translation: BAA84942.1.
RefSeqiYP_006320286.1. NC_017910.1.

Genome annotation databases

GeneIDi12953683.
KEGGiebt:EBL_c26960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB020481 Genomic DNA. Translation: BAA84942.1 .
RefSeqi YP_006320286.1. NC_017910.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1D2T X-ray 1.90 A 19-249 [» ]
1EOI X-ray 2.40 A/B/C 19-249 [» ]
1IW8 X-ray 2.50 A/B/C/D/E/F 19-249 [» ]
ProteinModelPortali Q9S1A6.
SMRi Q9S1A6. Positions 25-246.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 12953683.
KEGGi ebt:EBL_c26960.

Phylogenomic databases

KOi K09474.

Miscellaneous databases

EvolutionaryTracei Q9S1A6.

Family and domain databases

Gene3Di 1.20.144.10. 1 hit.
InterProi IPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view ]
Pfami PF01569. PAP2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSi PR00483. BACPHPHTASE.
SMARTi SM00014. acidPPc. 1 hit.
[Graphical view ]
SUPFAMi SSF48317. SSF48317. 1 hit.
PROSITEi PS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate."
    Ishikawa K., Mihara Y., Gondoh K., Suzuki E., Asano Y.
    EMBO J. 19:2412-2423(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JCM1650Imported.
  2. "Enhancement of nucleoside phosphorylation activity in an acid phosphatase."
    Ishikawa K., Mihara Y., Shimba N., Ohtsu N., Kawasaki H., Suzuki E., Asano Y.
    Protein Eng. 15:539-543(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 19-249.

Entry informationi

Entry nameiQ9S1A6_SHIBL
AccessioniPrimary (citable) accession number: Q9S1A6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3