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Protein

Acid phosphatase

Gene

pho

Organism
Shimwellia blattae (Escherichia blattae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.UniRule annotation

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Acid phosphataseUniRule annotation (EC:3.1.3.2UniRule annotation)
Gene namesi
Name:phoImported
OrganismiShimwellia blattae (Escherichia blattae)Imported
Taxonomic identifieri563 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShimwellia

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
  2. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1D2TX-ray1.90A19-249[»]
1EOIX-ray2.40A/B/C19-249[»]
1IW8X-ray2.50A/B/C/D/E/F19-249[»]
ProteinModelPortaliQ9S1A6.
SMRiQ9S1A6. Positions 25-246.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9S1A6.

Family & Domainsi

Sequence similaritiesi

Belongs to the class A bacterial acid phosphatase family.UniRule annotation

Phylogenomic databases

KOiK09474.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9S1A6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKRVLAVCF AALFSSQALA LVATGNDTTT KPDLYYLKNS EAINSLALLP
60 70 80 90 100
PPPAVGSIAF LNDQAMYEQG RLLRNTERGK LAAEDANLSS GGVANAFSGA
110 120 130 140 150
FGSPITEKDA PALHKLLTNM IEDAGDLATR SAKDHYMRIR PFAFYGVSTC
160 170 180 190 200
NTTEQDKLSK NGSYPSGHTS IGWATALVLA EINPQRQNEI LKRGYELGQS
210 220 230 240
RVICGYHWQS DVDAARVVGS AVVATLHTNP AFQQQLQKAK AEFAQHQKK
Length:249
Mass (Da):26,957
Last modified:May 1, 2000 - v1
Checksum:i7AEAE6CB61FC0CA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020481 Genomic DNA. Translation: BAA84942.1.
RefSeqiYP_006320286.1. NC_017910.1.

Genome annotation databases

GeneIDi12953683.
KEGGiebt:EBL_c26960.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB020481 Genomic DNA. Translation: BAA84942.1.
RefSeqiYP_006320286.1. NC_017910.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1D2TX-ray1.90A19-249[»]
1EOIX-ray2.40A/B/C19-249[»]
1IW8X-ray2.50A/B/C/D/E/F19-249[»]
ProteinModelPortaliQ9S1A6.
SMRiQ9S1A6. Positions 25-246.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi12953683.
KEGGiebt:EBL_c26960.

Phylogenomic databases

KOiK09474.

Miscellaneous databases

EvolutionaryTraceiQ9S1A6.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR011158. Acid_Pase_ClassA.
IPR001011. Acid_Pase_classA_bac.
IPR018296. Acid_Pase_classA_bac_CS.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTSiPR00483. BACPHPHTASE.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
PROSITEiPS01157. ACID_PHOSPH_CL_A. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate."
    Ishikawa K., Mihara Y., Gondoh K., Suzuki E., Asano Y.
    EMBO J. 19:2412-2423(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: JCM1650Imported.
  2. "Enhancement of nucleoside phosphorylation activity in an acid phosphatase."
    Ishikawa K., Mihara Y., Shimba N., Ohtsu N., Kawasaki H., Suzuki E., Asano Y.
    Protein Eng. 15:539-543(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 19-249, ACTIVE SITE.

Entry informationi

Entry nameiQ9S1A6_SHIBL
AccessioniPrimary (citable) accession number: Q9S1A6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: January 7, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.