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Q9S166

- Q9S166_STRGR

UniProt

Q9S166 - Q9S166_STRGR

Protein
Submitted name:

AdpA

Gene

adpA

Organism
Streptomyces griseus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AdpAImported
    Gene namesi
    Name:adpAImported
    OrganismiStreptomyces griseusImported
    Taxonomic identifieri1911 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3W6VX-ray2.95A215-340[»]
    ProteinModelPortaliQ9S166.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains HTH araC/xylS-type DNA-binding domain.SAAS annotation

    Phylogenomic databases

    OrthoDBiEOG651SXJ.

    Family and domain databases

    Gene3Di1.10.10.60. 2 hits.
    3.40.50.880. 1 hit.
    InterProiIPR029062. Class_I_gatase-like.
    IPR025628. DJ-1_InhA.
    IPR009057. Homeodomain-like.
    IPR018060. HTH_AraC.
    [Graphical view]
    PfamiPF13278. DUF4066. 1 hit.
    PF12833. HTH_18. 1 hit.
    [Graphical view]
    SMARTiSM00342. HTH_ARAC. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 2 hits.
    SSF52317. SSF52317. 1 hit.
    PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9S166-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQDSAAATE AARKLTGRRR REVVAVLLFS GGPIFESSIP LSVFGIDRQD    50
    AGVPRYRLLV CGGEEGPLRT TGGLELTAPY GLEAISRAGT VVVPAWRSIT 100
    SPPPAEALDA LRRAHEEGAR IVGLCTGAFV LAAAGLLDGR PATTHWMYAP 150
    TLAKRYPSVH VDPRELFVDD GDVLTSAGTA AGIDLCLHIV RTDHGTEAAG 200
    ALARRLVVPP RRSGGQERYL DRSLPEEIGS DPLAEVVAWA LEHLHEQFDV 250
    ETLAARAYMS RRTFDRRFRS LTGSAPLQWL ITQRVLQAQR LLETSDYSVD 300
    EVAGRCGFRS PVALRGHFRR QLGSSPAAYR AAYRARRPQG VAESAATVVE 350
    TMVPSQGPPS GRRGSTLSSA AVAVAASVGS GELSLPGPDA YVPGRPALPG 400
    QRSAP 405
    Length:405
    Mass (Da):43,167
    Last modified:May 1, 2000 - v1
    Checksum:i0126EDE469631A92
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB023785 Genomic DNA. Translation: BAA86265.1.
    PIRiT44488.

    Genome annotation databases

    PATRICi23756192. VBIStrGri32265_4849.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB023785 Genomic DNA. Translation: BAA86265.1 .
    PIRi T44488.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3W6V X-ray 2.95 A 215-340 [» ]
    ProteinModelPortali Q9S166.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    AraC-XylS Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    PATRICi 23756192. VBIStrGri32265_4849.

    Phylogenomic databases

    OrthoDBi EOG651SXJ.

    Family and domain databases

    Gene3Di 1.10.10.60. 2 hits.
    3.40.50.880. 1 hit.
    InterProi IPR029062. Class_I_gatase-like.
    IPR025628. DJ-1_InhA.
    IPR009057. Homeodomain-like.
    IPR018060. HTH_AraC.
    [Graphical view ]
    Pfami PF13278. DUF4066. 1 hit.
    PF12833. HTH_18. 1 hit.
    [Graphical view ]
    SMARTi SM00342. HTH_ARAC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 2 hits.
    SSF52317. SSF52317. 1 hit.
    PROSITEi PS01124. HTH_ARAC_FAMILY_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The A-factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus: identification of a target gene of the A-factor receptor."
      Ohnishi Y., Kameyama S., Onaka H., Horinouchi S.
      Mol. Microbiol. 34:102-111(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: IFO13350Imported.
    2. "Complex structure of the DNA-binding domain of AdpA, the global transcription factor in Streptomyces griseus, and a target duplex DNA reveals the structural basis of its tolerant DNA sequence specificity."
      Yao M.D., Ohtsuka J., Nagata K., Miyazono K., Zhi Y., Ohnishi Y., Tanokura M.
      J. Biol. Chem. 288:31019-31029(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.95 ANGSTROMS) OF 215-340.

    Entry informationi

    Entry nameiQ9S166_STRGR
    AccessioniPrimary (citable) accession number: Q9S166
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3