Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9RZC5

- Q9RZC5_DEIRA

UniProt

Q9RZC5 - Q9RZC5_DEIRA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acetylornithine/acetyl-lysine aminotransferase

Gene

argD

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in both the arginine and lysine biosynthetic pathways.UniRule annotation

Catalytic activityi

N(2)-acetyl-L-lysine + 2-oxoglutarate = N-acetyl-L-aminoadipate semialdehyde + L-glutamate.UniRule annotation
N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.UniRule annotation

Cofactori

Note: Binds 1 pyridoxal phosphate per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei157 – 1571Pyridoxal phosphate; via carbonyl oxygenUniRule annotation
Binding sitei160 – 1601N2-acetyl-L-ornithineUniRule annotation
Binding sitei321 – 3211N2-acetyl-L-ornithineUniRule annotation
Binding sitei322 – 3221Pyridoxal phosphateUniRule annotation

GO - Molecular functioni

  1. N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
  2. lysine biosynthetic process via aminoadipic acid Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotation, Lysine biosynthesisUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciDRAD243230:GH46-2720-MONOMER.
UniPathwayiUPA00033; UER00038.
UPA00068; UER00109.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylornithine/acetyl-lysine aminotransferaseUniRule annotation (EC:2.6.1.-UniRule annotation, EC:2.6.1.11UniRule annotation)
Short name:
ACOATUniRule annotation
Gene namesi
Name:argDUniRule annotation
Synonyms:lysJUniRule annotation
Ordered Locus Names:DR_A0029Imported
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Imported
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
ProteomesiUP000002524: Chromosome II

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei294 – 2941N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi243230.DR_A0029.

Structurei

3D structure databases

ProteinModelPortaliQ9RZC5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni265 – 2684Pyridoxal phosphate bindingUniRule annotation

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK00823.
OMAiMCGFYAE.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_01107. ArgD_aminotrans_3.
InterProiIPR004636. AcOrn/SuccOrn_fam.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9RZC5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTATQAKPRQ PDLKTSLPGP KTAEIMARDQ ATLSTSYMRP YPFVPDFGKG
60 70 80 90 100
VWLTDVDGNT MLDFFAGIAV STTGHAHPHV VQAVQRQIEK FTHVCLTDYP
110 120 130 140 150
QEITTSLAER LVKHVERPGE KWRVFFSNSG AEAVEAAVKL ARNHTGRQHI
160 170 180 190 200
ISTMGSFHGR TYGAITLTGS KTKYKRGFGP LLPAVSHVPY PNPFRPPLGS
210 220 230 240 250
TPENCGQAVI DHIESLFVGI LPADEVAAII VEPMQGEGGY IVPPADFLPG
260 270 280 290 300
LRALCDKHGI MLIFDEVQAG MGRTGKMFSF QHFDVQPDII TSAKGIASGM
310 320 330 340 350
PLGALLAKES VMTWPVGSHG STYGGNPVAA AASHATLDLL EGQVKHEGCG
360 370 380 390 400
DSLMDNAAQV GDFILGELKG MQDEFPFIGD VRGRGLFIGI EFVKPDGSPD
410 420 430 440 450
GALRDQASMM MFEKGLLNLD CGEAVIRISP PLILTREEAA TGLDIMRGVF

QELK
Length:454
Mass (Da):48,951
Last modified:May 1, 2000 - v1
Checksum:i32D698851A3B1D2D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001825 Genomic DNA. Translation: AAF12279.1.
PIRiG75595.
RefSeqiNP_285353.1. NC_001264.1.

Genome annotation databases

EnsemblBacteriaiAAF12279; AAF12279; DR_A0029.
GeneIDi1798195.
KEGGidra:DR_A0029.
PATRICi21633094. VBIDeiRad64572_2917.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001825 Genomic DNA. Translation: AAF12279.1 .
PIRi G75595.
RefSeqi NP_285353.1. NC_001264.1.

3D structure databases

ProteinModelPortali Q9RZC5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243230.DR_A0029.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF12279 ; AAF12279 ; DR_A0029 .
GeneIDi 1798195.
KEGGi dra:DR_A0029.
PATRICi 21633094. VBIDeiRad64572_2917.

Phylogenomic databases

HOGENOMi HOG000020206.
KOi K00823.
OMAi MCGFYAE.
OrthoDBi EOG6QVRHN.

Enzyme and pathway databases

UniPathwayi UPA00033 ; UER00038 .
UPA00068 ; UER00109 .
BioCyci DRAD243230:GH46-2720-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPi MF_01107. ArgD_aminotrans_3.
InterProi IPR004636. AcOrn/SuccOrn_fam.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422Imported.

Entry informationi

Entry nameiQ9RZC5_DEIRA
AccessioniPrimary (citable) accession number: Q9RZC5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 26, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3