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Protein
Submitted name:

Agmatinase

Gene

DR_A0149

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi121 – 1211Manganese 1; via pros nitrogenCombined sources
Metal bindingi143 – 1431Manganese 1Combined sources
Metal bindingi143 – 1431Manganese 2Combined sources
Metal bindingi145 – 1451Manganese 2; via pros nitrogenCombined sources
Metal bindingi147 – 1471Manganese 1Combined sources
Metal bindingi229 – 2291Manganese 1Combined sources
Metal bindingi229 – 2291Manganese 2Combined sources
Metal bindingi231 – 2311Manganese 2Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

ManganeseCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciDRAD243230:GH46-2840-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
AgmatinaseImported
Submitted name:
Agmatinase, putativeImported
Gene namesi
Ordered Locus Names:DR_A0149Imported
ORF Names:A2G07_14225Imported
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Imported
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome II

Interactioni

Protein-protein interaction databases

STRINGi243230.DR_A0149.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WOGX-ray1.80A/B/C/D/E/F1-304[»]
1WOHX-ray1.75A/B/C/D/E/F1-304[»]
1WOIX-ray1.85A/B/C/D/E/F1-304[»]
ProteinModelPortaliQ9RZ04.
SMRiQ9RZ04. Positions 3-304.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9RZ04.

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYW. Bacteria.
COG0010. LUCA.
HOGENOMiHOG000204320.
InParanoidiQ9RZ04.
KOiK01480.
OMAiVREAIWC.
OrthoDBiEOG6R2GW5.

Family and domain databases

Gene3Di3.40.800.10. 1 hit.
InterProiIPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERiPTHR11358. PTHR11358. 1 hit.
PfamiPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFiPIRSF036979. Arginase. 1 hit.
PROSITEiPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9RZ04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGPAHLPYG GIPTFARAPL VQPDGDWQAD VAALGVPFDI ALGFRPGARF
60 70 80 90 100
APRALREASL RSVPPFTGLD GKTRLQGVTF ADAGDVILPS LEPQLAHDRI
110 120 130 140 150
TEAARQVRGR CRVPVFLGGD HSVSYPLLRA FADVPDLHVV QLDAHLDFTD
160 170 180 190 200
TRNDTKWSNS SPFRRACEAL PNLVHITTVG LRGLRFDPEA VAAARARGHT
210 220 230 240 250
IIPMDDVTAD LAGVLAQLPR GQNVYFSVDV DGFDPAVIPG TSSPEPDGLT
260 270 280 290 300
YAQGMKILAA AAANNTVVGL DLVELAPNLD PTGRSELLMA RLVMETLCEV

FDHV
Length:304
Mass (Da):32,523
Last modified:May 1, 2000 - v1
Checksum:i97F826881D581182
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001825 Genomic DNA. Translation: AAF12214.1.
CP015082 Genomic DNA. Translation: ANC73005.1.
PIRiH75610.
RefSeqiNP_285473.1. NC_001264.1.
WP_010889409.1. NC_001264.1.

Genome annotation databases

EnsemblBacteriaiAAF12214; AAF12214; DR_A0149.
GeneIDi1798006.
KEGGidra:DR_A0149.
PATRICi21633334. VBIDeiRad64572_3036.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001825 Genomic DNA. Translation: AAF12214.1.
CP015082 Genomic DNA. Translation: ANC73005.1.
PIRiH75610.
RefSeqiNP_285473.1. NC_001264.1.
WP_010889409.1. NC_001264.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1WOGX-ray1.80A/B/C/D/E/F1-304[»]
1WOHX-ray1.75A/B/C/D/E/F1-304[»]
1WOIX-ray1.85A/B/C/D/E/F1-304[»]
ProteinModelPortaliQ9RZ04.
SMRiQ9RZ04. Positions 3-304.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243230.DR_A0149.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF12214; AAF12214; DR_A0149.
GeneIDi1798006.
KEGGidra:DR_A0149.
PATRICi21633334. VBIDeiRad64572_3036.

Phylogenomic databases

eggNOGiENOG4105CYW. Bacteria.
COG0010. LUCA.
HOGENOMiHOG000204320.
InParanoidiQ9RZ04.
KOiK01480.
OMAiVREAIWC.
OrthoDBiEOG6R2GW5.

Enzyme and pathway databases

BioCyciDRAD243230:GH46-2840-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9RZ04.

Family and domain databases

Gene3Di3.40.800.10. 1 hit.
InterProiIPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERiPTHR11358. PTHR11358. 1 hit.
PfamiPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFiPIRSF036979. Arginase. 1 hit.
PROSITEiPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422Imported and R1Imported.
  2. "Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily."
    Ahn H.J., Kim K.H., Lee J., Ha J.Y., Lee H.H., Kim D., Yoon H.J., Kwon A.R., Suh S.W.
    J. Biol. Chem. 279:50505-50513(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) IN COMPLEX WITH MANGANESE.
  3. "compelete genome sequence of the Extremely Radiation-Resistant Bacteria Deinococcus radiodurans R1."
    Hua X., Hua Y.
    Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: R1Imported.

Entry informationi

Entry nameiQ9RZ04_DEIRA
AccessioniPrimary (citable) accession number: Q9RZ04
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 6, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.