Agmatinase, putative - Deinococcus radiodurans

Preferred order of sections

Names and origin

Protein names

Submitted name:
Agmatinase, putative EMBL AAF12214.1

Gene names

Ordered Locus Names:

DR_A0149

Organism

Deinococcus radiodurans

Taxonomic identifier

1299 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Cofactor	Manganese By similarity. RuleBase RU003684
Sequence similarities	Belongs to the arginase family. RuleBase RU003684

Ontologies

Keywords
Ligand	Manganese RuleBase RU003684 Metal-binding RuleBase RU003684
Molecular function	Hydrolase RuleBase RU003684
Technical term	3D-structure PDB 1WOG PDB 1WOH PDB 1WOI Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

121

1

Manganese 1; via pros nitrogen PDB 1WOG PDB 1WOI

Metal binding

143

1

Manganese 1 PDB 1WOG PDB 1WOI

Metal binding

143

1

Manganese 2 PDB 1WOI

Metal binding

145

1

Manganese 2; via pros nitrogen PDB 1WOI

Metal binding

147

1

Manganese 1 PDB 1WOG PDB 1WOI

Metal binding

229

1

Manganese 1 PDB 1WOG PDB 1WOI

Metal binding

229

1

Manganese 2 PDB 1WOI

Metal binding

231

1

Manganese 2 PDB 1WOI

Sequences

Sequence

Length

Mass (Da)

Tools

Q9RZ04 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 97F826881D581182
Show »

FASTA

304

32,523

        10         20         30         40         50         60 
MSGPAHLPYG GIPTFARAPL VQPDGDWQAD VAALGVPFDI ALGFRPGARF APRALREASL 

        70         80         90        100        110        120 
RSVPPFTGLD GKTRLQGVTF ADAGDVILPS LEPQLAHDRI TEAARQVRGR CRVPVFLGGD 

       130        140        150        160        170        180 
HSVSYPLLRA FADVPDLHVV QLDAHLDFTD TRNDTKWSNS SPFRRACEAL PNLVHITTVG 

       190        200        210        220        230        240 
LRGLRFDPEA VAAARARGHT IIPMDDVTAD LAGVLAQLPR GQNVYFSVDV DGFDPAVIPG 

       250        260        270        280        290        300 
TSSPEPDGLT YAQGMKILAA AAANNTVVGL DLVELAPNLD PTGRSELLMA RLVMETLCEV 


FDHV

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1." White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D., Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L., Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M., Vamathevan J.J., Lam P. Fraser C.M. Science 286:1571-1577(1999) [PubMed: 10567266] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[2]	"Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily." Ahn H.J., Kim K.H., Lee J., Ha J.Y., Lee H.H., Kim D., Yoon H.J., Kwon A.R., Suh S.W. J. Biol. Chem. 279:50505-50513(2004) [PubMed: 15355972] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE001825 Genomic DNA. Translation: AAF12214.1.

PIR

H75610.

RefSeq

NP_285473.1. NC_001264.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1WOG	X-ray	1.80	A/B/C/D/E/F	1-304	[»]
1WOH	X-ray	1.75	A/B/C/D/E/F	1-304	[»]
1WOI	X-ray	1.85	A/B/C/D/E/F	1-304	[»]

ProteinModelPortal

Q9RZ04.

SMR

Q9RZ04. Positions 3-304.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1798006.

GenomeReviews

Gene locus DR_A0149 in contig AE001825_GR.

KEGG

dra:DR_A0149.

NMPDR

fig|243230.1.peg.2963.

PATRIC

21633334. VBIDeiRad64572_3036.

TIGR

DR_A0149.

Phylogenomic databases

HOGENOM

HBG391953.

PhylomeDB

Q9RZ04.

ProtClustDB

CLSK445765.

Family and domain databases

InterPro

IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]

Gene3D

G3DSA:3.40.800.10. Ureohydrolase. 1 hit.

KO

K01480.

PANTHER

PTHR11358. Ureohydrolase. 1 hit.

Pfam

PF00491. Arginase. 1 hit.
[Graphical view]

PIRSF

PIRSF036979. Arginase. 1 hit.

PROSITE

PS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9RZ04_DEIRA

Accession

Primary (citable) accession number: Q9RZ04

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)