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Protein

Aldehyde dehydrogenase

Gene

aldA

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei272By similarity1
Active sitei311By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi228 – 234NADBy similarity7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase (EC:1.2.1.3)
Gene namesi
Name:aldA
Ordered Locus Names:DR_A0348
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564471 – 515Aldehyde dehydrogenaseAdd BLAST515

Proteomic databases

PRIDEiQ9RYG9

Interactioni

Protein-protein interaction databases

STRINGi243230.DR_A0348

Structurei

3D structure databases

ProteinModelPortaliQ9RYG9
SMRiQ9RYG9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26 Bacteria
COG1012 LUCA
HOGENOMiHOG000271505
InParanoidiQ9RYG9
KOiK00138
OMAiTFVQEDV
OrthoDBiPOG091H09V0

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

Q9RYG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVAEQQPQH QGYANPGTPG SVVTFKKRYD NFIGGQWVPP VKGQYFDNAS
60 70 80 90 100
PVDGKVFTQA ARSTAEDVEL ALDAAHRAAP AWGRTSVTER SNILLKIADR
110 120 130 140 150
MEQNLEMLAV AETWDNGKPV RETLAADLPL AIDHFRYFAG CIRAQEGGLS
160 170 180 190 200
QIDDSTVAYH FHEPLGVVGQ IIPWNFPLLM GVWKLAPALA AGNAVVLKPA
210 220 230 240 250
EQTPASIMVL MELIADLLPE GVVNVVNGFG LEAGKPLASS PRIAKIAFTG
260 270 280 290 300
ETNTGRLIMG YAADNLIPVT LELGGKSPNI FFDDVMMEDD AFLDKAVEGM
310 320 330 340 350
VMFALNQGEV CTCPSRALIQ ESIYDRFMER AVQRVEAITM GHPLDPGTMI
360 370 380 390 400
GAQASTEQLD KILSYLDIGR AEGAEVLTGG ERGQREGLEE GFYVKPTIFK
410 420 430 440 450
GHNKMRIFQE EIFGPVLAAA TFKDEAEALE LANDTLYGLG AGLWTRDISR
460 470 480 490 500
AYRMGRGIQA GRVWTNCYHV YPAHAAFGGY KQSGIGRENH RMMLDHYQQT
510
KNLLVSYSPN KMGFF
Length:515
Mass (Da):56,409
Last modified:May 1, 2000 - v1
Checksum:iD8BB5DDF7D2DBBC0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001825 Genomic DNA Translation: AAF12436.1
AB003475 Genomic DNA Translation: BAA21372.1
PIRiH75589
RefSeqiNP_285671.1, NC_001264.1
WP_010889607.1, NZ_CP015082.1

Genome annotation databases

EnsemblBacteriaiAAF12436; AAF12436; DR_A0348
GeneIDi1798223
KEGGidra:DR_A0348
PATRICifig|243230.17.peg.3240

Similar proteinsi

Entry informationi

Entry nameiALDH_DEIRA
AccessioniPrimary (citable) accession number: Q9RYG9
Secondary accession number(s): O32502
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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