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Q9RY77 (PTA_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:DR_0073
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length702 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Sequence caution

The sequence AAF09663.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 702702Phosphate acetyltransferase
PRO_0000405546

Regions

Region375 – 702328Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
Q9RY77 [UniParc].

Last modified March 8, 2011. Version 2.
Checksum: 192F97376746F7D7

FASTA70274,665
        10         20         30         40         50         60 
MKTLFLAPTR NGVGLSSTAL GLARALERQS LKVAFLKPIA QTYEPRTDDS VHFARAVAHL 

        70         80         90        100        110        120 
TTPDPIPLTR AEELLSQGGE EDLMEQVIAL AREAAGEGSD VLIAEGLALN ERNVYAGTLN 

       130        140        150        160        170        180 
ARLARNLEAD TVLVSSLAGV TPAELADELE IAAQGYRRSD GSGLAGFVLN FAPRELDFGS 

       190        200        210        220        230        240 
LMAELRSRSR VLASGELPLL GVVSLDPALR QLRTLDVARA LDAEIINAGE AESRRVSSTV 

       250        260        270        280        290        300 
VTARSVPQMT NLFTSGALIV TPADREDVIM AAALSHLSGT PLAGLMYTSG SAPEATIQQL 

       310        320        330        340        350        360 
CEVALTSSLP VLRVPTNSFE TASRLVHLDF RVPHDDPRRM DRMLDYIADR LDTVPLGARL 

       370        380        390        400        410        420 
RAPGVAGERR LPPSAFRYEL IQRARAANKR IVLPEGDEPR TVKAAIRCTE KGIARCVLLA 

       430        440        450        460        470        480 
PPEKVRQVAQ GQGLELPEGL EIIDPETVRG KYVAPMVELR KSKGLTEPQA EAQLEDSVVL 

       490        500        510        520        530        540 
GTMMLALGEV DGLVSGAVHT TASTVRPALQ LIKTAPGSSL VSSVFFMLMP EQVLVYGDAA 

       550        560        570        580        590        600 
INPDPNAQEL ADIAIQSADS AHAFGIPVRV AMLSYSTGES GSGEDVEKVK EATKLVRERR 

       610        620        630        640        650        660 
PELLVDGPLQ YDAASVPSVG RSKAPDSPVA GRATVFIFPD LNTGNTTYKA VQRSAGVVAV 

       670        680        690        700 
GPMLQGLRKP VNDLSRGALV DDIVYTIALT AIQATQSAAD CG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF09663.1. Different initiation.
PIRG75563.
RefSeqNP_293799.1. NC_001263.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_0073.

Proteomic databases

PRIDEQ9RY77.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF09663; AAF09663; DR_0073.
GeneID1797525.
KEGGdra:DR_0073.
PATRIC21627619. VBIDeiRad64572_0236.

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053797.
KOK13788.
OrthoDBEOG6BKJ5W.

Enzyme and pathway databases

BioCycDRAD243230:GH46-78-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.1390.20. 1 hit.
3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr_N_like.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_DEIRA
AccessionPrimary (citable) accession number: Q9RY77
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 11, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways