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Protein

50S ribosomal protein L2

Gene

rplB

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L2
Gene namesi
Name:rplB
Ordered Locus Names:DR_0314
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00001295582 – 27550S ribosomal protein L2Add BLAST274

Proteomic databases

PRIDEiQ9RXJ9

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome (By similarity).By similarity

Protein-protein interaction databases

DIPiDIP-58602N
IntActiQ9RXJ9, 1 interactor
STRINGi243230.DR_0314

Structurei

Secondary structure

1275
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 10Combined sources3
Helixi11 – 13Combined sources3
Beta strandi22 – 24Combined sources3
Turni31 – 33Combined sources3
Beta strandi34 – 37Combined sources4
Beta strandi41 – 43Combined sources3
Beta strandi46 – 49Combined sources4
Beta strandi51 – 53Combined sources3
Beta strandi60 – 63Combined sources4
Beta strandi65 – 68Combined sources4
Helixi69 – 72Combined sources4
Beta strandi74 – 83Combined sources10
Turni86 – 88Combined sources3
Beta strandi92 – 97Combined sources6
Turni98 – 100Combined sources3
Beta strandi102 – 106Combined sources5
Beta strandi116 – 122Combined sources7
Beta strandi130 – 133Combined sources4
Beta strandi141 – 143Combined sources3
Turni149 – 151Combined sources3
Beta strandi153 – 155Combined sources3
Beta strandi158 – 161Combined sources4
Beta strandi163 – 167Combined sources5
Beta strandi170 – 176Combined sources7
Turni178 – 180Combined sources3
Beta strandi182 – 186Combined sources5
Beta strandi189 – 194Combined sources6
Beta strandi196 – 198Combined sources3
Helixi200 – 203Combined sources4
Helixi209 – 214Combined sources6
Beta strandi216 – 218Combined sources3
Helixi223 – 225Combined sources3
Helixi228 – 230Combined sources3
Beta strandi236 – 239Combined sources4
Beta strandi243 – 245Combined sources3
Beta strandi247 – 250Combined sources4
Beta strandi252 – 254Combined sources3
Helixi262 – 264Combined sources3
Helixi265 – 269Combined sources5
Beta strandi270 – 272Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NKWX-ray3.10A1-275[»]
1NWXX-ray3.50A2-275[»]
1NWYX-ray3.30A2-275[»]
1SM1X-ray3.42A1-275[»]
1XBPX-ray3.50A2-275[»]
2ZJPX-ray3.70A2-275[»]
2ZJQX-ray3.30A2-275[»]
2ZJRX-ray2.91A2-275[»]
3CF5X-ray3.30A2-275[»]
3DLLX-ray3.50A2-275[»]
3PIOX-ray3.25A2-275[»]
3PIPX-ray3.45A2-274[»]
4IO9X-ray3.20A2-275[»]
4IOAX-ray3.20A2-275[»]
4IOCX-ray3.60A2-275[»]
4U67X-ray3.65A1-275[»]
4V49X-ray8.70A4-273[»]
4V4AX-ray9.50A4-273[»]
4V4GX-ray11.50D4-273[»]
4WFNX-ray3.54A1-275[»]
5DM6X-ray2.90A2-275[»]
5DM7X-ray3.00A2-275[»]
5JVGX-ray3.43A1-275[»]
5JVHX-ray3.58A1-275[»]
ProteinModelPortaliQ9RXJ9
SMRiQ9RXJ9
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9RXJ9

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CFD Bacteria
COG0090 LUCA
HOGENOMiHOG000232982
InParanoidiQ9RXJ9
KOiK02886
OMAiHGYIKGV
OrthoDBiPOG091H01QE

Family and domain databases

Gene3Di2.30.30.30, 1 hit
4.10.950.10, 1 hit
HAMAPiMF_01320_B Ribosomal_L2_B, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR022666 Rbsml_prot_L2_RNA-bd_dom
IPR014722 Rib_L2_dom2
IPR002171 Ribosomal_L2
IPR005880 Ribosomal_L2_bac/org-type
IPR022669 Ribosomal_L2_C
IPR022671 Ribosomal_L2_CS
IPR014726 Ribosomal_L2_dom3
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR13691 PTHR13691, 1 hit
PfamiView protein in Pfam
PF00181 Ribosomal_L2, 1 hit
PF03947 Ribosomal_L2_C, 1 hit
PIRSFiPIRSF002158 Ribosomal_L2, 1 hit
SMARTiView protein in SMART
SM01383 Ribosomal_L2, 1 hit
SM01382 Ribosomal_L2_C, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR01171 rplB_bact, 1 hit
PROSITEiView protein in PROSITE
PS00467 RIBOSOMAL_L2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9RXJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVKKYRPYT PSRRQMTTAD FSGLTKKRPE KALTEALPKT GGRNNRGRIT
60 70 80 90 100
SRFIGGGHKR LYRIIDFKRR DKSGVNAKVA AIEYDPNRSA RIALLHYADG
110 120 130 140 150
EKRYILAPEG LTVGATVNAG PEAEPKLGNA LPLRFVPVGA VVHALELVPG
160 170 180 190 200
KGAQLARSAG TSVQVQGKES DYVIVRLPSG ELRRVHSECY ATIGAVGNAE
210 220 230 240 250
HKNIVLGKAG RSRWLGRKPH QRGSAMNPVD HPHGGGEGRT GAGRVPVTPW
260 270
GKPTKGLKTR RKRKTSDRFI VTRRK
Length:275
Mass (Da):30,045
Last modified:January 23, 2007 - v3
Checksum:iA96E5853B592C11E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA Translation: AAF09895.1
PIRiB75534
RefSeqiNP_294037.1, NC_001263.1
WP_010886959.1, NZ_CP015081.1

Genome annotation databases

EnsemblBacteriaiAAF09895; AAF09895; DR_0314
GeneIDi1798735
KEGGidra:DR_0314
PATRICifig|243230.17.peg.480

Similar proteinsi

Entry informationi

Entry nameiRL2_DEIRA
AccessioniPrimary (citable) accession number: Q9RXJ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 121 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

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