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Q9RXJ4

- RL29_DEIRA

UniProt

Q9RXJ4 - RL29_DEIRA

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Protein

50S ribosomal protein L29

Gene
rpmC, DR_0319
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Binds the 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-KW
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciDRAD243230:GH46-329-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L29
Gene namesi
Name:rpmC
Ordered Locus Names:DR_0319
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
ProteomesiUP000002524: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 676750S ribosomal protein L29UniRule annotationPRO_0000130383Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Contacts protein L23 and trigger factor when it is complexed with the ribosome (1 Publication and 1 Publication).9 Publications

Protein-protein interaction databases

STRINGi243230.DR_0319.

Structurei

Secondary structure

1
67
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni4 – 85
Helixi11 – 199
Helixi21 – 3414
Helixi40 – 6021
Turni61 – 655

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1NKWX-ray3.10W1-67[»]
1NWXX-ray3.50W1-67[»]
1NWYX-ray3.30W1-67[»]
1PNUX-ray8.70W2-66[»]
1PNYX-ray9.50W2-66[»]
1SM1X-ray3.42W1-67[»]
1VORX-ray11.50Y2-66[»]
1VOYX-ray11.50Y2-66[»]
1VP0X-ray11.50Y2-66[»]
1XBPX-ray3.50W1-67[»]
2AARX-ray3.50W1-67[»]
2D3OX-ray3.35W1-67[»]
2ZJPX-ray3.70V1-67[»]
2ZJQX-ray3.30V1-67[»]
2ZJRX-ray2.91V1-67[»]
3CF5X-ray3.30V1-67[»]
3DLLX-ray3.50V1-67[»]
3PIOX-ray3.25V1-67[»]
3PIPX-ray3.45V1-67[»]
4IO9X-ray3.20V1-67[»]
4IOAX-ray3.20V1-67[»]
4IOCX-ray3.60V1-67[»]
ProteinModelPortaliQ9RXJ4.
SMRiQ9RXJ4. Positions 1-66.

Miscellaneous databases

EvolutionaryTraceiQ9RXJ4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0255.
HOGENOMiHOG000248755.
KOiK02904.
OMAiMKPSDMR.
OrthoDBiEOG6VTK8Z.

Family and domain databases

Gene3Di1.10.287.310. 1 hit.
HAMAPiMF_00374. Ribosomal_L29.
InterProiIPR001854. Ribosomal_L29.
IPR018254. Ribosomal_L29_CS.
[Graphical view]
PfamiPF00831. Ribosomal_L29. 1 hit.
[Graphical view]
SUPFAMiSSF46561. SSF46561. 1 hit.
TIGRFAMsiTIGR00012. L29. 1 hit.
PROSITEiPS00579. RIBOSOMAL_L29. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9RXJ4-1 [UniParc]FASTAAdd to Basket

« Hide

MKPSEMRNLQ ATDFAKEIDA RKKELMELRF QAAAGQLAQP HRVRQLRREV   50
AQLNTVKAEL ARKGEQQ 67
Length:67
Mass (Da):7,760
Last modified:May 1, 2000 - v1
Checksum:iE4A9DB4CCE58932F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000513 Genomic DNA. Translation: AAF09900.1.
PIRiG75534.
RefSeqiNP_294042.1. NC_001263.1.

Genome annotation databases

EnsemblBacteriaiAAF09900; AAF09900; DR_0319.
GeneIDi1800092.
KEGGidra:DR_0319.
PATRICi21628136. VBIDeiRad64572_0485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000513 Genomic DNA. Translation: AAF09900.1 .
PIRi G75534.
RefSeqi NP_294042.1. NC_001263.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1NKW X-ray 3.10 W 1-67 [» ]
1NWX X-ray 3.50 W 1-67 [» ]
1NWY X-ray 3.30 W 1-67 [» ]
1PNU X-ray 8.70 W 2-66 [» ]
1PNY X-ray 9.50 W 2-66 [» ]
1SM1 X-ray 3.42 W 1-67 [» ]
1VOR X-ray 11.50 Y 2-66 [» ]
1VOY X-ray 11.50 Y 2-66 [» ]
1VP0 X-ray 11.50 Y 2-66 [» ]
1XBP X-ray 3.50 W 1-67 [» ]
2AAR X-ray 3.50 W 1-67 [» ]
2D3O X-ray 3.35 W 1-67 [» ]
2ZJP X-ray 3.70 V 1-67 [» ]
2ZJQ X-ray 3.30 V 1-67 [» ]
2ZJR X-ray 2.91 V 1-67 [» ]
3CF5 X-ray 3.30 V 1-67 [» ]
3DLL X-ray 3.50 V 1-67 [» ]
3PIO X-ray 3.25 V 1-67 [» ]
3PIP X-ray 3.45 V 1-67 [» ]
4IO9 X-ray 3.20 V 1-67 [» ]
4IOA X-ray 3.20 V 1-67 [» ]
4IOC X-ray 3.60 V 1-67 [» ]
ProteinModelPortali Q9RXJ4.
SMRi Q9RXJ4. Positions 1-66.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243230.DR_0319.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF09900 ; AAF09900 ; DR_0319 .
GeneIDi 1800092.
KEGGi dra:DR_0319.
PATRICi 21628136. VBIDeiRad64572_0485.

Phylogenomic databases

eggNOGi COG0255.
HOGENOMi HOG000248755.
KOi K02904.
OMAi MKPSDMR.
OrthoDBi EOG6VTK8Z.

Enzyme and pathway databases

BioCyci DRAD243230:GH46-329-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q9RXJ4.

Family and domain databases

Gene3Di 1.10.287.310. 1 hit.
HAMAPi MF_00374. Ribosomal_L29.
InterProi IPR001854. Ribosomal_L29.
IPR018254. Ribosomal_L29_CS.
[Graphical view ]
Pfami PF00831. Ribosomal_L29. 1 hit.
[Graphical view ]
SUPFAMi SSF46561. SSF46561. 1 hit.
TIGRFAMsi TIGR00012. L29. 1 hit.
PROSITEi PS00579. RIBOSOMAL_L29. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  2. "High resolution structure of the large ribosomal subunit from a mesophilic eubacterium."
    Harms J., Schluenzen F., Zarivach R., Bashan A., Gat S., Agmon I., Bartels H., Franceschi F., Yonath A.
    Cell 107:679-688(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 1-5, X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  3. "Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria."
    Schluenzen F., Zarivach R., Harms J., Bashan A., Tocilj A., Albrecht R., Yonath A., Franceschi F.
    Nature 413:814-821(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FIVE ANTIBIOTICS.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  4. "Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression."
    Bashan A., Agmon I., Zarivach R., Schluenzen F., Harms J., Berisio R., Bartels H., Franceschi F., Auerbach T., Hansen H.A., Kossoy E., Kessler M., Yonath A.
    Mol. Cell 11:91-102(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRNA MIMICS.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  5. "Structural basis for the antibiotic activity of ketolides and azalides."
    Schluenzen F., Harms J.M., Franceschi F., Hansen H.A., Bartels H., Zarivach R., Yonath A.
    Structure 11:329-338(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH MODIFIED MACROLIDE ANTIBIOTICS.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  6. "Structural insight into the role of the ribosomal tunnel in cellular regulation."
    Berisio R., Schluenzen F., Harms J., Bashan A., Auerbach T., Baram D., Yonath A.
    Nat. Struct. Biol. 10:366-370(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TROLEANDOMYCIN.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  7. "Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin."
    Harms J.M., Schluenzen F., Fucini P., Bartels H., Yonath A.
    BMC Biol. 2:4-4(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH THE STREPTOGRAMINS QUINUPRISTIN AND DALFOPRISTIN.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  8. "Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin."
    Schluenzen F., Pyetan E., Fucini P., Yonath A., Harms J.M.
    Mol. Microbiol. 54:1287-1294(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TIAMULIN.
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
  9. "Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action."
    Baram D., Pyetan E., Sittner A., Auerbach-Nevo T., Bashan A., Yonath A.
    Proc. Natl. Acad. Sci. U.S.A. 102:12017-12022(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRIGGER FACTOR.
  10. "The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction."
    Schluenzen F., Wilson D.N., Tian P., Harms J.M., McInnes S.J., Hansen H.A.S., Albrecht R., Buerger J., Wilbanks S.M., Fucini P.
    Structure 13:1685-1694(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.35 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRIGGER FACTOR.

Entry informationi

Entry nameiRL29_DEIRA
AccessioniPrimary (citable) accession number: Q9RXJ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi