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Q9RXJ4 (RL29_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L29
Gene names
Name:rpmC
Ordered Locus Names:DR_0319
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length67 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Binds the 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. HAMAP-Rule MF_00374

Subunit structure

Part of the 50S ribosomal subunit. Contacts protein L23 and trigger factor when it is complexed with the ribosome (Ref.9 and Ref.10). Ref.2 Ref.3 Ref.4 Ref.5 Ref.6 Ref.7 Ref.8 Ref.9 Ref.10

Sequence similarities

Belongs to the ribosomal protein L29P family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 676750S ribosomal protein L29 HAMAP-Rule MF_00374
PRO_0000130383

Secondary structure

.......... 67
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9RXJ4 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: E4A9DB4CCE58932F

FASTA677,760
        10         20         30         40         50         60 
MKPSEMRNLQ ATDFAKEIDA RKKELMELRF QAAAGQLAQP HRVRQLRREV AQLNTVKAEL 


ARKGEQQ 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1."
White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D., Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L., Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M., Vamathevan J.J., Lam P. expand/collapse author list , McDonald L.A., Utterback T.R., Zalewski C., Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D., Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
Science 286:1571-1577(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[2]"High resolution structure of the large ribosomal subunit from a mesophilic eubacterium."
Harms J., Schluenzen F., Zarivach R., Bashan A., Gat S., Agmon I., Bartels H., Franceschi F., Yonath A.
Cell 107:679-688(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-5, X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[3]"Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria."
Schluenzen F., Zarivach R., Harms J., Bashan A., Tocilj A., Albrecht R., Yonath A., Franceschi F.
Nature 413:814-821(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FIVE ANTIBIOTICS.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[4]"Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression."
Bashan A., Agmon I., Zarivach R., Schluenzen F., Harms J., Berisio R., Bartels H., Franceschi F., Auerbach T., Hansen H.A., Kossoy E., Kessler M., Yonath A.
Mol. Cell 11:91-102(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRNA MIMICS.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[5]"Structural basis for the antibiotic activity of ketolides and azalides."
Schluenzen F., Harms J.M., Franceschi F., Hansen H.A., Bartels H., Zarivach R., Yonath A.
Structure 11:329-338(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH MODIFIED MACROLIDE ANTIBIOTICS.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[6]"Structural insight into the role of the ribosomal tunnel in cellular regulation."
Berisio R., Schluenzen F., Harms J., Bashan A., Auerbach T., Baram D., Yonath A.
Nat. Struct. Biol. 10:366-370(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TROLEANDOMYCIN.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[7]"Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin."
Harms J.M., Schluenzen F., Fucini P., Bartels H., Yonath A.
BMC Biol. 2:4-4(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH THE STREPTOGRAMINS QUINUPRISTIN AND DALFOPRISTIN.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[8]"Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin."
Schluenzen F., Pyetan E., Fucini P., Yonath A., Harms J.M.
Mol. Microbiol. 54:1287-1294(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TIAMULIN.
Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.
[9]"Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action."
Baram D., Pyetan E., Sittner A., Auerbach-Nevo T., Bashan A., Yonath A.
Proc. Natl. Acad. Sci. U.S.A. 102:12017-12022(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRIGGER FACTOR.
[10]"The binding mode of the trigger factor on the ribosome: implications for protein folding and SRP interaction."
Schluenzen F., Wilson D.N., Tian P., Harms J.M., McInnes S.J., Hansen H.A.S., Albrecht R., Buerger J., Wilbanks S.M., Fucini P.
Structure 13:1685-1694(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.35 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRIGGER FACTOR.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF09900.1.
PIRG75534.
RefSeqNP_294042.1. NC_001263.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1NKWX-ray3.10W1-67[»]
1NWXX-ray3.50W1-67[»]
1NWYX-ray3.30W1-67[»]
1PNUX-ray8.70W2-66[»]
1PNYX-ray9.50W2-66[»]
1SM1X-ray3.42W1-67[»]
1XBPX-ray3.50W1-67[»]
2AARX-ray3.50W1-67[»]
2D3OX-ray3.35W1-67[»]
2ZJPX-ray3.70V1-67[»]
2ZJQX-ray3.30V1-67[»]
2ZJRX-ray2.91V1-67[»]
3CF5X-ray3.30V1-67[»]
3DLLX-ray3.50V1-67[»]
3PIOX-ray3.25V1-67[»]
3PIPX-ray3.45V1-67[»]
4IO9X-ray3.20V1-67[»]
4IOAX-ray3.20V1-67[»]
4IOCX-ray3.60V1-67[»]
ProteinModelPortalQ9RXJ4.
SMRQ9RXJ4. Positions 1-66.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_0319.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF09900; AAF09900; DR_0319.
GeneID1800092.
KEGGdra:DR_0319.
PATRIC21628136. VBIDeiRad64572_0485.

Phylogenomic databases

eggNOGCOG0255.
HOGENOMHOG000248755.
KOK02904.
OMAASIGQLD.
OrthoDBEOG6VTK8Z.
ProtClustDBPRK00306.

Enzyme and pathway databases

BioCycDRAD243230:GH46-329-MONOMER.

Family and domain databases

Gene3D1.10.287.310. 1 hit.
HAMAPMF_00374. Ribosomal_L29.
InterProIPR001854. Ribosomal_L29.
IPR018254. Ribosomal_L29_CS.
[Graphical view]
PfamPF00831. Ribosomal_L29. 1 hit.
[Graphical view]
SUPFAMSSF46561. SSF46561. 1 hit.
TIGRFAMsTIGR00012. L29. 1 hit.
PROSITEPS00579. RIBOSOMAL_L29. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9RXJ4.

Entry information

Entry nameRL29_DEIRA
AccessionPrimary (citable) accession number: Q9RXJ4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references