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Protein

50S ribosomal protein L5

Gene

rplE

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement (By similarity). Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L5
Gene namesi
Name:rplE
Ordered Locus Names:DR_0323
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001249231 – 18050S ribosomal protein L5Add BLAST180

Interactioni

Subunit structurei

Forms a bridge to the 30S subunit in the 70S ribosome (By similarity). Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 (CTC) subcomplex. Is known to contact the 5S rRNA, 23S rRNA and the P site tRNA.By similarity6 Publications

Protein-protein interaction databases

STRINGi243230.DR_0323.

Structurei

Secondary structure

1180
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 20Combined sources17
Beta strandi25 – 28Combined sources4
Beta strandi33 – 35Combined sources3
Beta strandi36 – 38Combined sources3
Beta strandi42 – 44Combined sources3
Helixi47 – 61Combined sources15
Beta strandi66 – 69Combined sources4
Beta strandi76 – 78Combined sources3
Beta strandi84 – 89Combined sources6
Beta strandi90 – 92Combined sources3
Helixi93 – 106Combined sources14
Turni107 – 110Combined sources4
Beta strandi111 – 113Combined sources3
Turni124 – 126Combined sources3
Beta strandi127 – 132Combined sources6
Beta strandi134 – 137Combined sources4
Beta strandi138 – 140Combined sources3
Helixi143 – 145Combined sources3
Beta strandi146 – 148Combined sources3
Beta strandi156 – 158Combined sources3
Helixi163 – 172Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NKWX-ray3.10D1-180[»]
1NWXX-ray3.50D1-180[»]
1NWYX-ray3.30D1-180[»]
1SM1X-ray3.42D1-180[»]
1XBPX-ray3.50D1-180[»]
2ZJPX-ray3.70D1-180[»]
2ZJQX-ray3.30D1-180[»]
2ZJRX-ray2.91D1-180[»]
3CF5X-ray3.30D1-180[»]
3DLLX-ray3.50D1-180[»]
3PIOX-ray3.25D1-180[»]
3PIPX-ray3.45D1-180[»]
4IO9X-ray3.20D1-180[»]
4IOAX-ray3.20D1-180[»]
4IOCX-ray3.60D1-180[»]
4U67X-ray3.65D1-180[»]
4V49X-ray8.70D2-179[»]
4V4AX-ray9.50D2-179[»]
4V4GX-ray11.50G2-179[»]
4WFNX-ray3.54D1-180[»]
5DM6X-ray2.90D3-179[»]
5DM7X-ray3.00D3-179[»]
ProteinModelPortaliQ9RXJ0.
SMRiQ9RXJ0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9RXJ0.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L5P family.Curated

Phylogenomic databases

eggNOGiENOG4105CW6. Bacteria.
COG0094. LUCA.
HOGENOMiHOG000231311.
InParanoidiQ9RXJ0.
KOiK02931.
OMAiEQVMFHE.
OrthoDBiPOG091H007J.

Family and domain databases

Gene3Di3.30.1440.10. 1 hit.
HAMAPiMF_01333_B. Ribosomal_L5_B. 1 hit.
InterProiIPR002132. Ribosomal_L5.
IPR020930. Ribosomal_L5_bac-type.
IPR031309. Ribosomal_L5_C.
IPR022803. Ribosomal_L5_domain.
IPR031310. Ribosomal_L5_N.
[Graphical view]
PfamiPF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMiSSF55282. SSF55282. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RXJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLKTKYND QVRPALMQQF GYSSVMAVPR IEKIVVNEGL GSSKEDSKAI
60 70 80 90 100
DKAAKELALI TLQKPIITKA KKSISNFKLR QGMPVGIKVT LRGERMYVFL
110 120 130 140 150
EKLINIGLPR IRDFRGINPN AFDGRGNYNL GIKEQLIFPE ITYDMVDKTR
160 170 180
GMDITIVTTA KTDEEARALL QSMGLPFRKQ
Length:180
Mass (Da):20,350
Last modified:May 1, 2000 - v1
Checksum:i755B760BA0E90F5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF09904.1.
PIRiC75535.
RefSeqiNP_294046.1. NC_001263.1.
WP_010886968.1. NZ_CP015081.1.

Genome annotation databases

EnsemblBacteriaiAAF09904; AAF09904; DR_0323.
GeneIDi1798348.
KEGGidra:DR_0323.
PATRICi21628144. VBIDeiRad64572_0489.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF09904.1.
PIRiC75535.
RefSeqiNP_294046.1. NC_001263.1.
WP_010886968.1. NZ_CP015081.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NKWX-ray3.10D1-180[»]
1NWXX-ray3.50D1-180[»]
1NWYX-ray3.30D1-180[»]
1SM1X-ray3.42D1-180[»]
1XBPX-ray3.50D1-180[»]
2ZJPX-ray3.70D1-180[»]
2ZJQX-ray3.30D1-180[»]
2ZJRX-ray2.91D1-180[»]
3CF5X-ray3.30D1-180[»]
3DLLX-ray3.50D1-180[»]
3PIOX-ray3.25D1-180[»]
3PIPX-ray3.45D1-180[»]
4IO9X-ray3.20D1-180[»]
4IOAX-ray3.20D1-180[»]
4IOCX-ray3.60D1-180[»]
4U67X-ray3.65D1-180[»]
4V49X-ray8.70D2-179[»]
4V4AX-ray9.50D2-179[»]
4V4GX-ray11.50G2-179[»]
4WFNX-ray3.54D1-180[»]
5DM6X-ray2.90D3-179[»]
5DM7X-ray3.00D3-179[»]
ProteinModelPortaliQ9RXJ0.
SMRiQ9RXJ0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243230.DR_0323.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF09904; AAF09904; DR_0323.
GeneIDi1798348.
KEGGidra:DR_0323.
PATRICi21628144. VBIDeiRad64572_0489.

Phylogenomic databases

eggNOGiENOG4105CW6. Bacteria.
COG0094. LUCA.
HOGENOMiHOG000231311.
InParanoidiQ9RXJ0.
KOiK02931.
OMAiEQVMFHE.
OrthoDBiPOG091H007J.

Miscellaneous databases

EvolutionaryTraceiQ9RXJ0.

Family and domain databases

Gene3Di3.30.1440.10. 1 hit.
HAMAPiMF_01333_B. Ribosomal_L5_B. 1 hit.
InterProiIPR002132. Ribosomal_L5.
IPR020930. Ribosomal_L5_bac-type.
IPR031309. Ribosomal_L5_C.
IPR022803. Ribosomal_L5_domain.
IPR031310. Ribosomal_L5_N.
[Graphical view]
PfamiPF00281. Ribosomal_L5. 1 hit.
PF00673. Ribosomal_L5_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002161. Ribosomal_L5. 1 hit.
SUPFAMiSSF55282. SSF55282. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRL5_DEIRA
AccessioniPrimary (citable) accession number: Q9RXJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: May 1, 2000
Last modified: November 2, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.