Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9RW24 (RPIA_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribose-5-phosphate isomerase A

EC=5.3.1.6
Alternative name(s):
Phosphoriboisomerase A
Short name=PRI
Gene names
Name:rpiA
Ordered Locus Names:DR_0845
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate By similarity. HAMAP-Rule MF_00170

Catalytic activity

D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00170

Sequence similarities

Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpentose-phosphate shunt, non-oxidative branch

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribose-5-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 226226Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170
PRO_0000158411

Regions

Region28 – 314Substrate binding By similarity
Region84 – 874Substrate binding By similarity
Region97 – 1004Substrate binding By similarity

Sites

Active site1061Proton acceptor By similarity
Binding site1241Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RW24 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 935A49012F19A11C

FASTA22624,236
        10         20         30         40         50         60 
MDLEALKKEA ALRSVALVQS GQRVGLGTGS TAKYAIEELG RKLAAGELSG IVGVSTSEAS 

        70         80         90        100        110        120 
EKLAREVGIP TEPLDPRPLD IAIDGADEIA PNLDLVKGLG GALVREKMTE VQAKRLIIIA 

       130        140        150        160        170        180 
DHTKLVTRLG EKAPLPIEIV PFGFLSTIER LREFLPGGRL RQPGAQPYVT DNGNYIFDAQ 

       190        200        210        220 
LPAEFDAREL ERRIKGTLGV VDTGLFLGMA ERAFVAAPDG VQELTR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF10424.1.
PIRC75467.
RefSeqNP_294569.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RW24.
SMRQ9RW24. Positions 3-225.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_0845.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF10424; AAF10424; DR_0845.
GeneID1799561.
KEGGdra:DR_0845.
PATRIC21629244. VBIDeiRad64572_1028.

Phylogenomic databases

eggNOGCOG0120.
HOGENOMHOG000276369.
KOK01807.
OMAASKHVET.
OrthoDBEOG67MF61.
ProtClustDBCLSK444742.

Enzyme and pathway databases

BioCycDRAD243230:GH46-867-MONOMER.
UniPathwayUPA00115; UER00412.

Family and domain databases

HAMAPMF_00170. Rib_5P_isom_A.
InterProIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERPTHR11934. PTHR11934. 1 hit.
PfamPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsTIGR00021. rpiA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPIA_DEIRA
AccessionPrimary (citable) accession number: Q9RW24
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways