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Protein

Ribose-5-phosphate isomerase A

Gene

rpiA

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.UniRule annotation

Catalytic activityi

D-ribose 5-phosphate = D-ribulose 5-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei106 – 1061Proton acceptorUniRule annotation
Binding sitei124 – 1241SubstrateUniRule annotation

GO - Molecular functioni

  1. ribose-5-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt, non-oxidative branch Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciDRAD243230:GH46-867-MONOMER.
UniPathwayiUPA00115; UER00412.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose-5-phosphate isomerase AUniRule annotation (EC:5.3.1.6UniRule annotation)
Alternative name(s):
Phosphoriboisomerase AUniRule annotation
Short name:
PRIUniRule annotation
Gene namesi
Name:rpiAUniRule annotation
Ordered Locus Names:DR_0845
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
ProteomesiUP000002524 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Ribose-5-phosphate isomerase APRO_0000158411Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi243230.DR_0845.

Structurei

3D structure databases

ProteinModelPortaliQ9RW24.
SMRiQ9RW24. Positions 3-225.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni28 – 314Substrate bindingUniRule annotation
Regioni84 – 874Substrate bindingUniRule annotation
Regioni97 – 1004Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the ribose 5-phosphate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0120.
HOGENOMiHOG000276369.
InParanoidiQ9RW24.
KOiK01807.
OMAiIQYIGER.
OrthoDBiEOG67MF61.

Family and domain databases

HAMAPiMF_00170. Rib_5P_isom_A.
InterProiIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERiPTHR11934. PTHR11934. 1 hit.
PfamiPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00021. rpiA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RW24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLEALKKEA ALRSVALVQS GQRVGLGTGS TAKYAIEELG RKLAAGELSG
60 70 80 90 100
IVGVSTSEAS EKLAREVGIP TEPLDPRPLD IAIDGADEIA PNLDLVKGLG
110 120 130 140 150
GALVREKMTE VQAKRLIIIA DHTKLVTRLG EKAPLPIEIV PFGFLSTIER
160 170 180 190 200
LREFLPGGRL RQPGAQPYVT DNGNYIFDAQ LPAEFDAREL ERRIKGTLGV
210 220
VDTGLFLGMA ERAFVAAPDG VQELTR
Length:226
Mass (Da):24,236
Last modified:May 1, 2000 - v1
Checksum:i935A49012F19A11C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF10424.1.
PIRiC75467.
RefSeqiNP_294569.1. NC_001263.1.

Genome annotation databases

EnsemblBacteriaiAAF10424; AAF10424; DR_0845.
GeneIDi1799561.
KEGGidra:DR_0845.
PATRICi21629244. VBIDeiRad64572_1028.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF10424.1.
PIRiC75467.
RefSeqiNP_294569.1. NC_001263.1.

3D structure databases

ProteinModelPortaliQ9RW24.
SMRiQ9RW24. Positions 3-225.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243230.DR_0845.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF10424; AAF10424; DR_0845.
GeneIDi1799561.
KEGGidra:DR_0845.
PATRICi21629244. VBIDeiRad64572_1028.

Phylogenomic databases

eggNOGiCOG0120.
HOGENOMiHOG000276369.
InParanoidiQ9RW24.
KOiK01807.
OMAiIQYIGER.
OrthoDBiEOG67MF61.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00412.
BioCyciDRAD243230:GH46-867-MONOMER.

Family and domain databases

HAMAPiMF_00170. Rib_5P_isom_A.
InterProiIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERiPTHR11934. PTHR11934. 1 hit.
PfamiPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00021. rpiA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.

Entry informationi

Entry nameiRPIA_DEIRA
AccessioniPrimary (citable) accession number: Q9RW24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: May 1, 2000
Last modified: January 7, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.