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Q9RVV9 (RPOB_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta
Short name=RNAP subunit beta
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta
Transcriptase subunit beta
Gene names
Name:rpoB
Ordered Locus Names:DR_0912
OrganismDeinococcus radiodurans
Taxonomic identifier1299 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length1159 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_01321

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_01321

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta chain family.

Sequence caution

The sequence AAF10490.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionDNA binding

Inferred from electronic annotation. Source: InterPro

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

ribonucleoside binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11591159DNA-directed RNA polymerase subunit beta HAMAP MF_01321
PRO_0000047891

Sequences

Sequence LengthMass (Da)Tools
Q9RVV9 [UniParc].

Last modified September 11, 2007. Version 2.
Checksum: C68FF0DE7838FDB9

FASTA1,159128,735
        10         20         30         40         50         60 
MTLSKTPPRI ERFGDITEVI PLPNLTEVQV NSFKAFLQDD KAPDQREDVG LQSAFREVFP 

        70         80         90        100        110        120 
IDESEKGRST GMVLDFIEYR LGEPEYSPEE CREKDLTYEA PLYVKLELIH KDTGVIKGFK 

       130        140        150        160        170        180 
PDSPPESWVF LGNLPLMTFD GSFIINGADR VVISQIHRSP GVYFTSSYKG IKKQYTAAII 

       190        200        210        220        230        240 
PMPKRGPWIE LEFAGDVLEM KVNKRKFPVS LLLRVLGMDD ASIRALFTEF TPEVEPGEDK 

       250        260        270        280        290        300 
SAGMGADEAL LRLFTVLRPG DPPKRDKAIQ YLFGLLADPR RYDLGEPGRF KMNTKLGVQR 

       310        320        330        340        350        360 
QERTLLKFED GKFSDAGLVD TIRYLMALQQ GLETVPMVDE DGVVTDVPVA EDDIDHLGNR 

       370        380        390        400        410        420 
RVRTVGELLA DQLRVGMGRM ARGVRERMLL GNPDAATPTK LVNNRPIVAA MREFFGRSQL 

       430        440        450        460        470        480 
SQFKDQTNPL SDLRHKRRIS ALGPGGLTRE RAGFDVRDVH RTHYGRICPI ETPEGANIGL 

       490        500        510        520        530        540 
ISSLSSYAKV NDLGFIMAPY RKVEDGKVTN QVEYMTADIE DRYTIAQANS PLNEDNTFAD 

       550        560        570        580        590        600 
ERVLARRKGD PLLYTPDEVD YMDVSPKQIV SINTSLIPFL EHDDANRALM GSNMQSQAVP 

       610        620        630        640        650        660 
LVRADSPAVG TGVERRVVTD SGTSVVSDVN GRVSYVDARA IQVTLSEDHR ELNMNAGNVR 

       670        680        690        700        710        720 
TFELIRFTRS NQGTNLDQHP IVSVGDEVKV GQVIADGPAS ERGRLALGQN ITIAIMPFDG 

       730        740        750        760        770        780 
FNFEDAICIN EDLVRQDFYT SVHIEKDEIE ARDTKLGPEK ITRDIPGLSE AALRDLDEDG 

       790        800        810        820        830        840 
IVRVGAEVKP GDILVGKTSF KGESEPTPEE RLLRSIFGEK AREVKDTSLR VQSGQGGIVV 

       850        860        870        880        890        900 
KTVRFRRGDE GVDLKPGVRE MVRVYVAQKR QLQVGDKVAN RHGNKGVVSK IVRPEDMPYL 

       910        920        930        940        950        960 
EDGTPVDIVF NPLGVPSRMN LGQILETHLG EVARLTGQKF ETPVFDSVTE ATIKEMLEVA 

       970        980        990       1000       1010       1020 
AAERLQARKD DGFELDKREQ EVLDRAGKLG VIDAPGDDYE KGQMQLARTG KSILYDGRTG 

      1030       1040       1050       1060       1070       1080 
EPISGPVVVG IMYVMKLYHM VEDKLHARST GPYSLITQQP LGGKAQFGGQ RFGEMEVWAL 

      1090       1100       1110       1120       1130       1140 
EAYGAAHVLQ EMLTIKSDDI DGRDAAYQSI VKGEEVSGST IPESFKVLVK ELHSLGLDVE 

      1150 
VLDHGDKAVD IFEGMMPKR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000513 Genomic DNA. Translation: AAF10490.1. Different initiation.
PIRG75459.
RefSeqNP_294636.1. NC_001263.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1798818.
GenomeReviewsGene locus DR_0912 in contig AE000513_GR.
KEGGdra:DR_0912.
NMPDRfig|243230.1.peg.1095.
PATRIC21629390. VBIDeiRad64572_1099.
TIGRDR_0912.

Phylogenomic databases

HOGENOMHBG285547.
OMAIGRNKTY.
PhylomeDBQ9RVV9.
ProtClustDBPRK00405.

Enzyme and pathway databases

BioCycDRAD243230:DR_0912-MONOMER.

Family and domain databases

HAMAPMF_01321. RNApol_bact_RpoB.
[Tree]
InterProIPR010243. DNA-dir_RNA_pol_bsu_bac-type.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
Gene3DG3DSA:2.30.150.10. G3DSA:2.30.150.10. 1 hit.
G3DSA:2.40.270.10. G3DSA:2.40.270.10. 2 hits.
G3DSA:2.40.50.150. Ribosomal_L2. 1 hit.
KOK03043.
PANTHERPTHR20856:SF3. PTHR20856:SF3. 1 hit.
PTHR20856. RNA_pol_I_sub2. 1 hit.
PfamPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsTIGR02013. RpoB. 1 hit.
PROSITEPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRPOB_DEIRA
AccessionPrimary (citable) accession number: Q9RVV9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: September 11, 2007
Last modified: January 25, 2012
This is version 67 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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