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Q9RV76 (ALLB_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allantoinase

EC=3.5.2.5
Alternative name(s):
Allantoin-utilizing enzyme
Gene names
Name:allB
Ordered Locus Names:DR_1153
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring By similarity. HAMAP-Rule MF_01645

Catalytic activity

(S)-allantoin + H2O = allantoate. HAMAP-Rule MF_01645

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_01645

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1. HAMAP-Rule MF_01645

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01645

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity. HAMAP-Rule MF_01645

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Allantoinase HAMAP-Rule MF_01645
PRO_0000165941

Sites

Metal binding601Zinc 1 By similarity
Metal binding621Zinc 1 By similarity
Metal binding1471Zinc 1; via carbamate group By similarity
Metal binding1471Zinc 2; via carbamate group By similarity
Metal binding1831Zinc 2 By similarity
Metal binding2391Zinc 2 By similarity
Metal binding3121Zinc 1 By similarity

Amino acid modifications

Modified residue1471N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RV76 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 3215965D0613AF86

FASTA44848,559
        10         20         30         40         50         60 
MSLDLLLRGA VLVTPEGERR ADLGIVGGQI AELTDEIATP AAQTLDVSGL HVFPGVLDDH 

        70         80         90        100        110        120 
VHLNEPGRTH WEGFETGTQA LAAGGATSFL DMPLNSSPPV LTRERFEDKA RLGEEKSLID 

       130        140        150        160        170        180 
FGLWGGLTPL NLDQLDDLAE CGVIGLKAFM SHSGLDEFPA ADDLTLYEGM RTAKRHGLVV 

       190        200        210        220        230        240 
ATHAESNEFT RRLTETARAQ GKSGVRDYLE SRPVVTELEA VQRALLFAQD TGAALHLVHV 

       250        260        270        280        290        300 
SSGAAVALAY EGKQKGIDVT IETCPHYLHF TGEDVERVGA ALKCAPPLRD PAVQEELWRE 

       310        320        330        340        350        360 
LLAGHIDTVG SDHSPAPPDM KTSEDFFSLW GGISGAQSTL NVMLEDGYAQ RGLPLEIIAA 

       370        380        390        400        410        420 
LLALNPAQRF GLPQKGRLAV GADADFALVA LGEKFTLDTL YDRWQQNPYR GQSFQGRVHA 

       430        440 
TYLRGQPVYQ NGEFTGTPRG RLLRPRSL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF10727.1.
PIRE75429.
RefSeqNP_294877.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RV76.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_1153.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF10727; AAF10727; DR_1153.
GeneID1798402.
KEGGdra:DR_1153.
PATRIC21629898. VBIDeiRad64572_1350.

Phylogenomic databases

eggNOGCOG0044.
HOGENOMHOG000219146.
KOK01466.
OMACSPWEGH.
OrthoDBEOG6KHFW6.

Enzyme and pathway databases

BioCycDRAD243230:GH46-1180-MONOMER.
UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D2.30.40.10. 1 hit.
HAMAPMF_01645. Hydantoinase.
InterProIPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLB_DEIRA
AccessionPrimary (citable) accession number: Q9RV76
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways