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Protein

Citrate lyase subunit beta-like protein

Gene

DR_1240

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in fatty acid biosynthesis.Curated

Cofactori

Mg2+1 PublicationNote: Binds 1 Mg2+ ion per subunit.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei74 – 741Substrate1 Publication
Metal bindingi129 – 1291Magnesium1 Publication
Binding sitei129 – 1291Substrate1 Publication
Metal bindingi155 – 1551Magnesium1 Publication

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciDRAD243230:GH46-1267-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate lyase subunit beta-like protein (EC:4.1.-.-)
Gene namesi
Ordered Locus Names:DR_1240
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284Citrate lyase subunit beta-like proteinPRO_0000286387Add
BLAST

Interactioni

Subunit structurei

Homotrimer.1 Publication

Protein-protein interaction databases

STRINGi243230.DR_1240.

Structurei

Secondary structure

1
284
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi9 – 157Combined sources
Helixi19 – 246Combined sources
Turni25 – 284Combined sources
Beta strandi31 – 388Combined sources
Helixi45 – 6521Combined sources
Beta strandi69 – 746Combined sources
Helixi83 – 864Combined sources
Helixi87 – 893Combined sources
Beta strandi94 – 996Combined sources
Helixi105 – 11713Combined sources
Beta strandi124 – 1285Combined sources
Helixi131 – 1355Combined sources
Helixi137 – 1415Combined sources
Beta strandi146 – 1516Combined sources
Helixi153 – 1608Combined sources
Helixi169 – 1713Combined sources
Helixi172 – 18514Combined sources
Beta strandi188 – 1914Combined sources
Helixi200 – 21213Combined sources
Beta strandi216 – 2227Combined sources
Helixi223 – 2308Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SGJX-ray1.84A/B/C1-284[»]
ProteinModelPortaliQ9RUZ0.
SMRiQ9RUZ0. Positions 4-234.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9RUZ0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CI0. Bacteria.
COG2301. LUCA.
HOGENOMiHOG000242281.
InParanoidiQ9RUZ0.
KOiK01644.
OMAiWAYFGAE.
OrthoDBiPOG091H08ZB.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
InterProiIPR005000. Aldolase/citrate-lyase_domain.
IPR011206. Citrate_lyase_beta/mcl1/mcl2.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PANTHERiPTHR32308. PTHR32308. 1 hit.
PfamiPF03328. HpcH_HpaI. 1 hit.
[Graphical view]
PIRSFiPIRSF015582. Cit_lyase_B. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RUZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAPPALLRS VLFAPGNRAD LIAKLPRSAP DAVVIDLEDA VPGTAEAKAA
60 70 80 90 100
ARPVAHDAAR DLIAAAPHLA VFVRVNALHS PYFEDDLSVL TPELSGVVVP
110 120 130 140 150
KLEMGAEARQ VAQMLQERSL PLPILAGLET GAGVWNAREI MEVPEVAWAY
160 170 180 190 200
FGAEDYTTDL GGKRTPGGLE VLYARSQVAL AARLTGVAAL DIVVTALNDP
210 220 230 240 250
ETFRADAEQG RALGYSGKLC IHPAQVALAH EYFGPTEADR ARARALLDAA
260 270 280
AAAAQRGHGA FSFEGQMVDE PMLAKARTLL SHEA
Length:284
Mass (Da):29,980
Last modified:May 1, 2000 - v1
Checksum:iF95B6C9B20F89EC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF10813.1.
PIRiF75418.
RefSeqiNP_294964.1. NC_001263.1.
WP_010887883.1. NC_001263.1.

Genome annotation databases

EnsemblBacteriaiAAF10813; AAF10813; DR_1240.
GeneIDi1798759.
KEGGidra:DR_1240.
PATRICi21630068. VBIDeiRad64572_1435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF10813.1.
PIRiF75418.
RefSeqiNP_294964.1. NC_001263.1.
WP_010887883.1. NC_001263.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SGJX-ray1.84A/B/C1-284[»]
ProteinModelPortaliQ9RUZ0.
SMRiQ9RUZ0. Positions 4-234.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243230.DR_1240.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF10813; AAF10813; DR_1240.
GeneIDi1798759.
KEGGidra:DR_1240.
PATRICi21630068. VBIDeiRad64572_1435.

Phylogenomic databases

eggNOGiENOG4105CI0. Bacteria.
COG2301. LUCA.
HOGENOMiHOG000242281.
InParanoidiQ9RUZ0.
KOiK01644.
OMAiWAYFGAE.
OrthoDBiPOG091H08ZB.

Enzyme and pathway databases

BioCyciDRAD243230:GH46-1267-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ9RUZ0.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
InterProiIPR005000. Aldolase/citrate-lyase_domain.
IPR011206. Citrate_lyase_beta/mcl1/mcl2.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PANTHERiPTHR32308. PTHR32308. 1 hit.
PfamiPF03328. HpcH_HpaI. 1 hit.
[Graphical view]
PIRSFiPIRSF015582. Cit_lyase_B. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCITEL_DEIRA
AccessioniPrimary (citable) accession number: Q9RUZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

This organism lacks the other subunits that are necessary for ATP-independent citrate lyase activity. Even though this protein has clear similarity to citrate lyase beta subunit, it is expected to have a somewhat different enzyme activity.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.