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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei131 – 1311UniRule annotation
Active sitei503 – 5031UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciDRAD243230:GH46-1312-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:DR_1283Imported
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Imported
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
ProteomesiUP000002524: Chromosome I

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi243230.DR_1283.

Structurei

3D structure databases

ProteinModelPortaliQ9RUU8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
InParanoidiQ9RUU8.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9RUU8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALNNDVNRL GRILGQVLKE QEGEAFFNLV EQTRTLVREV RAGGDPAQLN
60 70 80 90 100
ALLGSLSEND ASNLARAFTW YFQLVNIAEE YERVRVLQSR SGVRSQSLAQ
110 120 130 140 150
ALADLREQGL SAEDVENLLA RVNLELTFTA HPTEMRRRTV RSHLEHIARE
160 170 180 190 200
LPDLGRESAQ ERVAAHVEAL WRTPELRRLK PTVLDEVKGG LNYISTIAQA
210 220 230 240 250
LPKLERDLSD AFQATYGRET AAHVPLRFSS WMGGDRDGNP FVTPEATREA
260 270 280 290 300
LQLHRERARE LLLAALRQAY TDLSQEEEED AAEGTYRTEL RALHNAVRDG
310 320 330 340 350
EPVELLPRLE ALNARLHADG QERTAWQLLM PLLSVARVFG QHLVSLDIRE
360 370 380 390 400
HSGQTGAAVA ELLKAAGVEA DYLGLSEDAK LELLTRELRS HRPLWPAGAT
410 420 430 440 450
FTETLEAVIG PIREVQAAAR RVGPLAFGHY VISMSESVSD ILEPLILARE
460 470 480 490 500
VGFRVLPVPL FETLDDLQHA PRIVTDLLAL PEYRAVLGDD MQEIMIGYSD
510 520 530 540 550
SNKDAGFLAA NWALHEAQRT ISDVCRRAGV RWRFFHGRGT SIGRGGGPAS
560 570 580 590 600
RAILGQPAGT IDAGVRITEQ GEALADKYSH PVLARRNLEQ ALYGVLLAAA
610 620 630 640 650
RPVGDPPADF MAAMTRAAEA SATAYRDFVH DPDFLPFFER VTPIHEISRL
660 670 680 690 700
NIASRPVRRP GAPTLGNLRA IPWVMSWTQN RANLPGWYGL AEGLAEIGPE
710 720 730 740 750
LAAKMYAEWP FFHSMLDNAQ MSLAKSDPLV FAEYLTLLEG ASTRLADHLR
760 770 780 790 800
ESYARTVAAV ESVIGGELML GEQRLKESIA LRNPYIDPIH RLQVELLRRS
810 820
RSHEGGLDEY ERPLLLTLQG IAAGVRNTG
Length:829
Mass (Da):91,909
Last modified:May 1, 2000 - v1
Checksum:iB3352FF2FBA14234
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF10853.1.
PIRiF75415.
RefSeqiNP_295007.1. NC_001263.1.

Genome annotation databases

EnsemblBacteriaiAAF10853; AAF10853; DR_1283.
GeneIDi1799219.
KEGGidra:DR_1283.
PATRICi21630160. VBIDeiRad64572_1479.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF10853.1.
PIRiF75415.
RefSeqiNP_295007.1. NC_001263.1.

3D structure databases

ProteinModelPortaliQ9RUU8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243230.DR_1283.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF10853; AAF10853; DR_1283.
GeneIDi1799219.
KEGGidra:DR_1283.
PATRICi21630160. VBIDeiRad64572_1479.

Phylogenomic databases

HOGENOMiHOG000238647.
InParanoidiQ9RUU8.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciDRAD243230:GH46-1312-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422Imported.

Entry informationi

Entry nameiQ9RUU8_DEIRA
AccessioniPrimary (citable) accession number: Q9RUU8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: February 4, 2015
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.