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Q9RUP2 (PGK_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:DR_1342
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length411 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 411411Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145939

Regions

Nucleotide binding369 – 3724ATP By similarity
Region41 – 433Substrate binding By similarity
Region79 – 824Substrate binding By similarity

Sites

Binding site561Substrate By similarity
Binding site1391Substrate By similarity
Binding site1721Substrate By similarity
Binding site2221ATP By similarity
Binding site3101ATP; via carbonyl oxygen By similarity
Binding site3411ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RUP2 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 39407D5EC7E34D37

FASTA41142,899
        10         20         30         40         50         60 
MTGLCPLHQP SPLDHPHSGG TPMQNLSQLD VKGKRVLVRV DYNVPVGDGV VQDDTRITAS 

        70         80         90        100        110        120 
VPTIKKLLDG GASVVLMSHF GRPKNGPEDK YSLKPVAEAV SRALGQDVKF IPSLPGSDET 

       130        140        150        160        170        180 
LQAVQALRPG EVALLENVRF EAGEEKNDAA LNDKLAKLGD AFVLDAFGSA HRAHSSVSGV 

       190        200        210        220        230        240 
AGKLPHAAGG LLQSEVDALG KLLHAPEHPY VVIIGGAKVS DKIKVIENLL PKVDRMLIGG 

       250        260        270        280        290        300 
GMMFTFIKAR GGQIGNSLVE DDQLDLAKGL LEKYGDKLLL PTDAVAADKF AADAQSKVVP 

       310        320        330        340        350        360 
ADQIPDGWMG LDIGPDTQRA YADALQGAKT VFWNGPMGVF EFDQFAAGTN AVAAAVGSLK 

       370        380        390        400        410 
DQAYTVVGGG DSVSAINKSG KADQIDHIST GGGASLELLE GKELPGVVAM A 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF10913.1.
PIRD75408.
RefSeqNP_295065.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RUP2.
SMRQ9RUP2. Positions 23-407.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_1342.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF10913; AAF10913; DR_1342.
GeneID1799396.
KEGGdra:DR_1342.
PATRIC21630282. VBIDeiRad64572_1539.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAAGHPVGK.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycDRAD243230:GH46-1371-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_DEIRA
AccessionPrimary (citable) accession number: Q9RUP2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways