ID   MSRB_DEIRA              Reviewed;         157 AA.
AC   Q9RUK6;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   16-JUN-2009, entry version 54.
DE   RecName: Full=Peptide methionine sulfoxide reductase msrB;
DE            EC=1.8.4.12;
DE   AltName: Full=Peptide-methionine (R)-S-oxide reductase;
GN   Name=msrB; OrderedLocusNames=DR_1378;
OS   Deinococcus radiodurans.
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales;
OC   Deinococcaceae; Deinococcus.
OX   NCBI_TaxID=1299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / IFO 15346 / LMG 4051 / NCIB 9279 / R1;
RX   MEDLINE=20036896; PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus
RT   radiodurans R1.";
RL   Science 286:1571-1577(1999).
CC   -!- CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide +
CC       H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin.
CC   -!- SIMILARITY: Belongs to the msrB Met sulfoxide reductase family.
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DR   EMBL; AE000513; AAF10947.1; -; Genomic_DNA.
DR   PIR; C75404; C75404.
DR   RefSeq; NP_295101.1; -.
DR   HSSP; P14930; 1L1D.
DR   GeneID; 1798862; -.
DR   GenomeReviews; AE000513_GR; DR_1378.
DR   KEGG; dra:DR_1378; -.
DR   NMPDR; fig|243230.1.peg.1560; -.
DR   TIGR; DR_1378; -.
DR   HOGENOM; Q9RUK6; -.
DR   OMA; Q9RUK6; KYESGCG.
DR   BioCyc; DRAD243230:DR_1378-MON; -.
DR   BRENDA; 1.8.4.12; 96172.
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase ac...; IEA:EC.
DR   GO; GO:0008113; F:peptide-methionine-(S)-S-oxide reductase ac...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_01400; -; 1.
DR   InterPro; IPR002579; Methionine_sulphoxide_MsrB.
DR   Gene3D; G3DSA:2.170.150.20; MsrB; 1.
DR   Pfam; PF01641; SelR; 1.
DR   ProDom; PD004057; DUF25; 1.
DR   TIGRFAMs; TIGR00357; MsrB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    157       Peptide methionine sulfoxide reductase
FT                                msrB.
FT                                /FTId=PRO_0000140270.
FT   ACT_SITE    126    126       Nucleophile (By similarity).
SQ   SEQUENCE   157 AA;  17661 MW;  CE8A0624F6E41B1E CRC64;
     MTQDTKTDFQ KPSDNDLRER LTPIQYQVTQ HEGTERAFTG EYWDHDEDGI YVDVVSGEPL
     FSSLDKYDAG CGWPSFTQPI PDVALTENTD YKIGYARTEV RSASADSHLG HVFPDGPRDR
     GGLRYCINSA ALRFVPLSEL DAQGYGQYRA LFEGRQG
//