Q9RUI6 (COMB_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	DR_1400

Organism

Deinococcus radiodurans

Taxonomic identifier

1299 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081468

Sequences

	Sequence		Length	Mass (Da)
	Q9RUI6 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 487C45A5C6B32736	FASTA	240	24,598
	10 20 30 40 50 60 MRLRVDLLPD SHYPDVALVI DVLRATTTAV TLLEQGAAEL LLTRTTEAAL AVRETVPDVL 70 80 90 100 110 120 LAGERGGLTI PGFDLGNSPV EVSGGAVAGR RVVMTTTNGT IAAHRAAQTA RHVVLAALVN 130 140 150 160 170 180 AHAVARHALA VASEEIAIVC AGTDGRVGLD DVYAAGVIAE YLLALGDFQV DDGARIALTM 190 200 210 220 230 240 RRGGGDPGEA LRSSGHGATL ARLGLSSDVD YAAQLSTSRL IPTLVPGDDV PAGALRFLAG

References

[1]

"Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1." White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D., Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L., Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M., Vamathevan J.J., Lam P. , McDonald L.A., Utterback T.R., Zalewski C., Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D., Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Science 286:1571-1577(1999) [PubMed: 10567266] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000513 Genomic DNA. Translation: AAF10969.1.
PIR	H75400.
RefSeq	NP_295123.1. NC_001263.1.
3D structure databases
ProteinModelPortal	Q9RUI6.
SMR	Q9RUI6. Positions 1-227.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1799160.
GenomeReviews	Gene locus DR_1400 in contig AE000513_GR.
KEGG	dra:DR_1400.
NMPDR	fig|243230.1.peg.1582.
PATRIC	21630398. VBIDeiRad64572_1597.
TIGR	DR_1400.
Phylogenomic databases
HOGENOM	HBG633644.
OMA	GWEGAYS.
PhylomeDB	Q9RUI6.
ProtClustDB	PRK14100.
Enzyme and pathway databases
BioCyc	DRAD243230:DR_1400-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_DEIRA

Accession

Primary (citable) accession number: Q9RUI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program