Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9RU48

- SODC_DEIRA

UniProt

Q9RU48 - SODC_DEIRA

Protein

Superoxide dismutase [Cu-Zn]

Gene

sodC

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.By similarity

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.

    Cofactori

    Binds 1 copper ion per subunit.Curated
    Binds 1 zinc ion per subunit.Curated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi69 – 691Copper; catalyticBy similarity
    Metal bindingi71 – 711Copper; catalyticBy similarity
    Metal bindingi95 – 951Copper; catalyticBy similarity
    Metal bindingi95 – 951Zinc; structuralBy similarity
    Metal bindingi104 – 1041Zinc; structuralBy similarity
    Metal bindingi115 – 1151Zinc; structuralBy similarity
    Metal bindingi118 – 1181Zinc; structuralBy similarity

    GO - Molecular functioni

    1. copper ion binding Source: RefGenome
    2. superoxide dismutase activity Source: RefGenome
    3. zinc ion binding Source: RefGenome

    GO - Biological processi

    1. removal of superoxide radicals Source: RefGenome

    Keywords - Molecular functioni

    Antioxidant, Oxidoreductase

    Keywords - Ligandi

    Copper, Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciDRAD243230:GH46-1576-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Cu-Zn] (EC:1.15.1.1)
    Gene namesi
    Name:sodC
    Ordered Locus Names:DR_1546
    OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
    Taxonomic identifieri243230 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
    ProteomesiUP000002524: Chromosome I

    Subcellular locationi

    Cell membrane PROSITE-ProRule annotation; Lipid-anchor PROSITE-ProRule annotation

    GO - Cellular componenti

    1. periplasmic space Source: RefGenome
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919PROSITE-ProRule annotationAdd
    BLAST
    Chaini20 – 182163Superoxide dismutase [Cu-Zn]PRO_0000032841Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi20 – 201N-palmitoyl cysteinePROSITE-ProRule annotation
    Lipidationi20 – 201S-diacylglycerol cysteinePROSITE-ProRule annotation
    Disulfide bondi76 ↔ 175By similarity

    Keywords - PTMi

    Disulfide bond, Lipoprotein, Palmitate

    Proteomic databases

    PRIDEiQ9RU48.

    Interactioni

    Protein-protein interaction databases

    STRINGi243230.DR_1546.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9RU48.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cu-Zn superoxide dismutase family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG2032.
    HOGENOMiHOG000263448.
    KOiK04565.
    OMAiEIEVKLH.
    OrthoDBiEOG6K13RS.

    Family and domain databases

    Gene3Di2.60.40.200. 1 hit.
    InterProiIPR001424. SOD_Cu_Zn_dom.
    [Graphical view]
    PfamiPF00080. Sod_Cu. 1 hit.
    [Graphical view]
    SUPFAMiSSF49329. SSF49329. 1 hit.
    PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9RU48-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFRTLTVVPL LALGLSLSAC ADLGQPTVRA DLLDQTGKVT GTATFSPSPI    50
    GTRVSIEVSG LKAGPHGLHI HENPNCNPGP DAQGQTIPFG AAGGHFDPGA 100
    SHNHDGPHAR NDQGHGGDLP MITVGEDGKG RLNFDTNRLK MTGPTGVLGR 150
    SIVIHADADD YQTNPAGNSG GRERCGVFQA IN 182
    Length:182
    Mass (Da):18,787
    Last modified:May 1, 2000 - v1
    Checksum:i96749572F393CA1A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000513 Genomic DNA. Translation: AAF11107.1.
    PIRiB75383.
    RefSeqiNP_295269.1. NC_001263.1.
    WP_010888185.1. NC_001263.1.

    Genome annotation databases

    EnsemblBacteriaiAAF11107; AAF11107; DR_1546.
    GeneIDi1797544.
    KEGGidra:DR_1546.
    PATRICi21630704. VBIDeiRad64572_1748.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000513 Genomic DNA. Translation: AAF11107.1 .
    PIRi B75383.
    RefSeqi NP_295269.1. NC_001263.1.
    WP_010888185.1. NC_001263.1.

    3D structure databases

    ProteinModelPortali Q9RU48.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243230.DR_1546.

    Proteomic databases

    PRIDEi Q9RU48.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAF11107 ; AAF11107 ; DR_1546 .
    GeneIDi 1797544.
    KEGGi dra:DR_1546.
    PATRICi 21630704. VBIDeiRad64572_1748.

    Phylogenomic databases

    eggNOGi COG2032.
    HOGENOMi HOG000263448.
    KOi K04565.
    OMAi EIEVKLH.
    OrthoDBi EOG6K13RS.

    Enzyme and pathway databases

    BioCyci DRAD243230:GH46-1576-MONOMER.

    Family and domain databases

    Gene3Di 2.60.40.200. 1 hit.
    InterProi IPR001424. SOD_Cu_Zn_dom.
    [Graphical view ]
    Pfami PF00080. Sod_Cu. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49329. SSF49329. 1 hit.
    PROSITEi PS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422.

    Entry informationi

    Entry nameiSODC_DEIRA
    AccessioniPrimary (citable) accession number: Q9RU48
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2002
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    Lacks the last conserved histidine that binds copper.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3