Reviewed, UniProtKB/Swiss-Prot Q9RU10 (MURI_DEIRA)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	DR_1586

Organism

Deinococcus radiodurans [Complete proteome] [HAMAP]

Taxonomic identifier

1299 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	290 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 290	290	Glutamate racemase HAMAP MF_00258		PRO_0000095469

Sequences

	Sequence		Length	Mass (Da)
	Q9RU10-1 [UniParc]. Last modified December 1, 2000. Version 2. Checksum: 24DA8793B10FDB8C	FASTA	290	30,144
	10 20 30 40 50 60 MPPVSFAAAS DPAPRSALPI GVFDSGAGGL SVLAELQRAL PQEDVLYLAD TAHVPYGARS 70 80 90 100 110 120 DEDIRDLTAR AVAELVRRGV KAVVVACNTA SAFSLTHLRE RFELPIIGLV PAVKPAVAAT 130 140 150 160 170 180 KSGVVGVLAT PGTLRGTLLA DVIRQWAEPA GVRVMQAVST ELVPLVEAGK ADSPEARVVL 190 200 210 220 230 240 RDVLEPLAEA GADQLVLGCT HYPFLAGSIR AEFGDTFALV DSGAAVARHT RNVLSRGGLL 250 260 270 280 290 RGGDRTGEVS YLTTSDPAHL RALLMTLRPG GADGASLPDP PSPRIELTTT

References

[1]

"Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1." White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D., Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L., Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M., Vamathevan J.J., Lam P. , McDonald L.A., Utterback T.R., Zalewski C., Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D., Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Science 286:1571-1577(1999) [PubMed: 10567266] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13939 / DSM 20539 / IFO 15346 / LMG 4051 / NCIB 9279 / R1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000513 Genomic DNA. Translation: AAF11147.1. Different initiation.
PIR	C75378.
RefSeq	NP_295309.1.
3D structure databases
SMR	Q9RU10. Positions 18-258.
ModBase	Search...
Genome annotation databases
GeneID	1799495.
GenomeReviews	Gene locus DR_1586 in contig AE000513_GR.
KEGG	dra:DR_1586.
NMPDR	fig|243230.1.peg.1768.
TIGR	DR_1586.
Phylogenomic databases
HOGENOM	HBG645102.
OMA	VITQPCP.
Enzyme and pathway databases
BioCyc	DRAD243230:DR_1586-MONOMER.
BRENDA	5.1.1.3. 96172.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_DEIRA

Accession

Primary (citable) accession number: Q9RU10

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	February 9, 2010
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)