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Q9RTL8 (G6PI_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:DR_1742
OrganismDeinococcus radiodurans
Taxonomic identifier1299 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473

Subcellular location

Cytoplasm By similarity HAMAP MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Glucose-6-phosphate isomerase HAMAP MF_00473
PRO_0000180637

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5041 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RTL8 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 5D34EB0FDA349CF5

FASTA54160,165
        10         20         30         40         50         60 
MSRLTDLPAW QALEDHYYEL QGTHLRELFA ADPERGEKMN AEGAGLYLDY SKHRVTDETL 

        70         80         90        100        110        120 
RLLRELAQAT GVEARRDAMF RGEKINVTEG RAVLHTALRA PRDAVIEVDG KNVVPEVHEV 

       130        140        150        160        170        180 
LDRMATFADA VRSGEWLGYT GKPIKNIVNI GIGGSDLGPV MAYEALKHYA QRDLTVRFVS 

       190        200        210        220        230        240 
NVDGTDLTEK TRDLDPEVTL FIVSSKTFTT QETMTNARSA RKWLLGSLKD DAAVTRHFVA 

       250        260        270        280        290        300 
VSTNAEEVQK FGIDTANMFG FWDWVGGRYS MDSAIGLSLM VAVGPEHFRE MLAGFHDMDE 

       310        320        330        340        350        360 
HFRTAPAEQN LPMLMGLLGV WYGDFFGAES LAVLPYDQYL ASFPAYLQQL DMESNGKHVT 

       370        380        390        400        410        420 
LGGEPVDYQT GPIVWGQAGT NGQHAFYQLI HQGTKLIPCD FIGFCQTLNP LPPHHDLLMA 

       430        440        450        460        470        480 
NVFAQTEALA FGKTLEQVLA DGVAPEVAPH RVFEGNRPTS TILADRLTPR TLGALIALYE 

       490        500        510        520        530        540 
HKVFVQGAVW DINSFDQWGV ELGKVLAKKI DGELQSEGEP ELQHDSSTNA LIRRYRARRQ 


G

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000513 Genomic DNA. Translation: AAF11299.1.
PIRC75358.
RefSeqNP_295465.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RTL8.
SMRQ9RTL8. Positions 2-540.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1799343.
GenomeReviewsGene locus DR_1742 in contig AE000513_GR.
KEGGdra:DR_1742.
NMPDRfig|243230.1.peg.1924.
PATRIC21631114. VBIDeiRad64572_1952.
TIGRDR_1742.

Phylogenomic databases

HOGENOMHBG352954.
OMAVDEHFRN.
PhylomeDBQ9RTL8.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycDRAD243230:DR_1742-MONOMER.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
[Tree]
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
Gene3DG3DSA:1.10.1390.10. G6P_Isomerase_C. 1 hit.
KOK01810.
PANTHERPTHR11469. G6P_Isomerase. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_DEIRA
AccessionPrimary (citable) accession number: Q9RTL8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: May 1, 2000
Last modified: January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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