Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA helicase

Gene

DR_1775

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei12ATP analog; via carbonyl oxygenCombined sources1
Binding sitei17ATP analogCombined sources1
Binding sitei258ATP analogCombined sources1
Binding sitei577ATP analogCombined sources1
Binding sitei617ATP analogCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 40ATP analogCombined sources6
Nucleotide bindingi290 – 291ATP analogCombined sources2

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HelicaseSAAS annotationImported, Hydrolase

Keywords - Ligandi

ATP-binding, DNA-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDRAD243230:GH46-1806-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA helicaseSAAS annotation (EC:3.6.4.12SAAS annotation)
Gene namesi
Ordered Locus Names:DR_1775Imported
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)Imported
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome I

Interactioni

Protein-protein interaction databases

DIPiDIP-48319N.
STRINGi243230.DR_1775.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4C2TX-ray4.00A/B/C/D1-745[»]
4C2UX-ray2.55A/D1-665[»]
4C30X-ray3.00A/D/F/I1-665[»]
ProteinModelPortaliQ9RTI9.
SMRiQ9RTI9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the helicase family. UvrD subfamily.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105C4R. Bacteria.
COG0210. LUCA.
HOGENOMiHOG000033016.
InParanoidiQ9RTI9.
KOiK03657.
OMAiHYRTQKG.
OrthoDBiPOG091H01Y3.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9RTI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSAGPDLL QALNPTQAQA ADHFTGPALV IAGAGSGKTR TLIYRIAHLI
60 70 80 90 100
GHYGVHPGEI LAVTFTNKAA AEMRERAGHL VPGAGDLWMS TFHSAGVRIL
110 120 130 140 150
RTYGEHIGLR RGFVIYDDDD QLDIIKEVMG SIPGIGAETQ PRVIRGIIDR
160 170 180 190 200
AKSNLWTPDD LDRSREPFIS GLPRDAAAEA YRRYEVRKKG QNAIDFGDLI
210 220 230 240 250
TETVRLFKEV PGVLDKVQNK AKFIHVDEYQ DTNRAQYELT RLLASRDRNL
260 270 280 290 300
LVVGDPDQSI YKFRGADIQN ILDFQKDYPD AKVYMLEHNY RSSARVLEAA
310 320 330 340 350
NKLIENNTER LDKTLKPVKE AGQPVTFHRA TDHRAEGDYV ADWLTRLHGE
360 370 380 390 400
GRAWSEMAIL YRTNAQSRVI EESLRRVQIP ARIVGGVGFY DRREIRDILA
410 420 430 440 450
YARLALNPAD DVALRRIIGR PRRGIGDTAL QKLMEWARTH HTSVLTACAN
460 470 480 490 500
AAEQNILDRG AHKATEFAGL MEAMSEAADN YEPAAFLRFV METSGYLDLL
510 520 530 540 550
RQEGQEGQVR LENLEELVSA AEEWSQDEAN VGGSIADFLD DAALLSSVDD
560 570 580 590 600
MRTKAENKGA PEDAVTLMTL HNAKGLEFPV VFIVGVEQGL LPSKGAIAEG
610 620 630 640 650
PSGIEEERRL FYVGITRAME RLLMTAAQNR MQFGKTNAAE DSAFLEDIEG
660 670 680 690 700
LFDTVDPYGQ PIEYRAKTWK QYRPTVPAAT TAVKNTSPLT AELAYRGGEQ
710 720 730 740
VKHPKFGEGQ VLAVAGVGER QEVTVHFASA GTKKLMVKFA NLTKL
Length:745
Mass (Da):82,597
Last modified:May 1, 2000 - v1
Checksum:iA4946F40E5FCD309
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF11329.1.
PIRiE75354.
RefSeqiNP_295498.1. NC_001263.1.
WP_010888410.1. NZ_CP015081.1.

Genome annotation databases

EnsemblBacteriaiAAF11329; AAF11329; DR_1775.
GeneIDi1800142.
KEGGidra:DR_1775.
PATRICi21631186. VBIDeiRad64572_1987.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF11329.1.
PIRiE75354.
RefSeqiNP_295498.1. NC_001263.1.
WP_010888410.1. NZ_CP015081.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4C2TX-ray4.00A/B/C/D1-745[»]
4C2UX-ray2.55A/D1-665[»]
4C30X-ray3.00A/D/F/I1-665[»]
ProteinModelPortaliQ9RTI9.
SMRiQ9RTI9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48319N.
STRINGi243230.DR_1775.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF11329; AAF11329; DR_1775.
GeneIDi1800142.
KEGGidra:DR_1775.
PATRICi21631186. VBIDeiRad64572_1987.

Phylogenomic databases

eggNOGiENOG4105C4R. Bacteria.
COG0210. LUCA.
HOGENOMiHOG000033016.
InParanoidiQ9RTI9.
KOiK03657.
OMAiHYRTQKG.
OrthoDBiPOG091H01Y3.

Enzyme and pathway databases

BioCyciDRAD243230:GH46-1806-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9RTI9_DEIRA
AccessioniPrimary (citable) accession number: Q9RTI9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.