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Q9RSY5 (KITH_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family.

Ontologies

Keywords
   Biological processDNA synthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

thymidine kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 212212Thymidine kinase HAMAP-Rule MF_00124
PRO_0000174970

Regions

Nucleotide binding16 – 238ATP By similarity
Nucleotide binding99 – 1024ATP By similarity

Sites

Active site1001Proton acceptor Potential

Sequences

Sequence LengthMass (Da)Tools
Q9RSY5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 5ACD76A28C6F88A8

FASTA21222,398
        10         20         30         40         50         60 
MLRSPYSGGH LEVVVGPMFS GKSEELIRRL TRSLIARQRV AVFKPAIDNR YHASEVASHA 

        70         80         90        100        110        120 
GRTLEAVAVP DAQAIRAQLS GQGELLSAAP EGVDVIGIDE AQFFGPELVP LVLELADAGV 

       130        140        150        160        170        180 
RVVLAGLDLD FRAEPFGSMP ELLARAESVD KLTAICTVCG APATRTQRLI GGQPARFDDP 

       190        200        210 
VVLVGAQESY EALPRAPHRA QGGVTTPSPL AS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF11536.1.
PIRC75330.
RefSeqNP_295707.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RSY5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_1984.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF11536; AAF11536; DR_1984.
GeneID1800380.
KEGGdra:DR_1984.
PATRIC21631628. VBIDeiRad64572_2207.

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076390.
KOK00857.
OMADHISEST.
OrthoDBEOG69D3J2.

Enzyme and pathway databases

BioCycDRAD243230:GH46-2018-MONOMER.
BRENDA2.7.1.21. 1856.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKITH_DEIRA
AccessionPrimary (citable) accession number: Q9RSY5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families