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Protein

50S ribosomal protein L7/L12

Gene

rplL

Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation (Probable).Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7/L12UniRule annotation
Gene namesi
Name:rplLUniRule annotation
Ordered Locus Names:DR_2043
OrganismiDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Taxonomic identifieri243230 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002524 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001575261 – 12250S ribosomal protein L7/L12Add BLAST122

Proteomic databases

PRIDEiQ9RST0.

Interactioni

Subunit structurei

Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors (Probable).Curated

Protein-protein interaction databases

STRINGi243230.DR_2043.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ZJQX-ray3.3051-122[»]
ProteinModelPortaliQ9RST0.
SMRiQ9RST0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9RST0.

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial ribosomal protein bL12 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KBC. Bacteria.
COG0222. LUCA.
HOGENOMiHOG000248813.
InParanoidiQ9RST0.
KOiK02935.
OMAiVDNAPKP.
OrthoDBiPOG091H0232.

Family and domain databases

CDDicd00387. Ribosomal_L7_L12. 1 hit.
Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12. 1 hit.
InterProiView protein in InterPro
IPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
PANTHERiPTHR24089:SF404. PTHR24089:SF404. 1 hit.
PfamiView protein in Pfam
PF00542. Ribosomal_L12. 1 hit.
PF16320. Ribosomal_L12_N. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001326. Ribosomal_L7/L12_C. 1 hit.
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RST0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYDKQALID QLGQLTIMEL ADLIDGLKET WGVTAAVAVS GGGAGAASPA
60 70 80 90 100
AEEKTEFDVV LIDAGASKIN VIKEIRGITG LGLKEAKDMS EKGGVLKEGV
110 120
AKDEAEKMKA QLEAAGARVE LK
Length:122
Mass (Da):12,628
Last modified:May 1, 2000 - v1
Checksum:i50C083F54FA79A23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000513 Genomic DNA. Translation: AAF11590.1.
PIRiD75323.
RefSeqiNP_295766.1. NC_001263.1.
WP_010888675.1. NZ_CP015081.1.

Genome annotation databases

EnsemblBacteriaiAAF11590; AAF11590; DR_2043.
GeneIDi1797932.
KEGGidra:DR_2043.
PATRICifig|243230.17.peg.2270.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL7_DEIRA
AccessioniPrimary (citable) accession number: Q9RST0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 2000
Last modified: June 7, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families