true2004-03-152024-03-27137RL6_DEIRAGenome sequence of the radioresistant bacterium Deinococcus radiodurans R1.White O.Eisen J.A.Heidelberg J.F.Hickey E.K.Peterson J.D.Dodson R.J.Haft D.H.Gwinn M.L.Nelson W.C.Richardson D.L.Moffat K.S.Qin H.Jiang L.Pamphile W.Crosby M.Shen M.Vamathevan J.J.Lam P.McDonald L.A.Utterback T.R.Zalewski C.Makarova K.S.Aravind L.Daly M.J.Minton K.W.Fleischmann R.D.Ketchum K.A.Nelson K.E.Salzberg S.L.Smith H.O.Venter J.C.Fraser C.M.doi:10.1126/science.286.5444.15711999Science2861571-1577NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1High resolution structure of the large ribosomal subunit from a mesophilic eubacterium.Harms J.Schluenzen F.Zarivach R.Bashan A.Gat S.Agmon I.Bartels H.Franceschi F.Yonath A.doi:10.1016/s0092-8674(01)00546-32001Cell107679-688X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNITPROTEIN SEQUENCE OF 1-5Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.Schluenzen F.Zarivach R.Harms J.Bashan A.Tocilj A.Albrecht R.Yonath A.Franceschi F.doi:10.1038/351015442001Nature413814-821X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH FIVE ANTIBIOTICSStructural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression.Bashan A.Agmon I.Zarivach R.Schluenzen F.Harms J.Berisio R.Bartels H.Franceschi F.Auerbach T.Hansen H.A.Kossoy E.Kessler M.Yonath A.doi:10.1016/s1097-2765(03)00009-12003Mol. Cell1191-102X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TRNA MIMICSStructural basis for the antibiotic activity of ketolides and azalides.Schluenzen F.Harms J.M.Franceschi F.Hansen H.A.Bartels H.Zarivach R.Yonath A.doi:10.1016/s0969-2126(03)00022-42003Structure11329-338X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH MODIFIED MACROLIDE ANTIBIOTICSStructural insight into the role of the ribosomal tunnel in cellular regulation.Berisio R.Schluenzen F.Harms J.Bashan A.Auerbach T.Baram D.Yonath A.doi:10.1038/nsb9152003Nat. Struct. Biol.10366-370X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TROLEANDOMYCINAlterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin.Harms J.M.Schluenzen F.Fucini P.Bartels H.Yonath A.doi:10.1186/1741-7007-2-42004BMC Biol.24X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH THE STREPTOGRAMINS QUINUPRISTIN AND DALFOPRISTINInhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.Schluenzen F.Pyetan E.Fucini P.Yonath A.Harms J.M.doi:10.1111/j.1365-2958.2004.04346.x2004Mol. Microbiol.541287-1294X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF THE 50S SUBUNIT IN COMPLEX WITH TIAMULINDifferent initiation.3.10E=1-1853.50E=1-1853.30E=1-1853.42E=1-1853.50E=1-1853.70E=1-1853.30E=1-1852.91E=1-1853.30E=1-1853.50E=1-1853.25E=1-1853.45E=1-1853.20E=1-1853.20E=1-1853.60E=1-1853.65E=1-1858.70E=5-1819.50E=5-18111.50H=5-1813.54E=1-1852.90E=5-1753.00E=5-1753.43E=1-1853.58E=1-1853.30E=5-1753.22E=5-1753.40E=5-1751BacteriaRibosomal protein L6, alpha-beta domainRibosomal_uL6_BRibosomal_uL6-likeRibosomal_uL6-like_a/b-dom_sfRibosomal_uL6_a/b-domRibosomal_uL6_bac-typeL6_bact54S RIBOSOMAL PROTEIN L6, MITOCHONDRIAL60S/50S RIBOSOMAL PROTEIN L6/L9Ribosomal_L6Ribosomal_L6RIBOSOMALL6Ribosomal protein L6Large ribosomal subunit protein uL650S ribosomal protein L6rplFDR_2111It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity). This protein binds to the 23S rRNA, and is important in its secondary structure.Part of the 50S ribosomal subunit.Belongs to the universal ribosomal protein uL6 family.Large ribosomal subunit protein uL6195821185161820222527333639414345475257596079839195991021051081111131151211241301361381501561581611642004-03-15219582accb4a7e73c38c2273f36d1cee0d2871MSRIGKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGKAGATGGKGKKtruetruetruetruetruetruetruetruetruetrue