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Q9RSC5 (PYRF_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:DR_2200
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Orotidine 5'-phosphate = UMP + CO2. HAMAP-Rule MF_01200

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2. HAMAP-Rule MF_01200

Sequence similarities

Belongs to the OMP decarboxylase family. Type 2 subfamily.

Sequence caution

The sequence AAF11749.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01200
PRO_0000134626

Sites

Active site921Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RSC5 [UniParc].

Last modified January 23, 2002. Version 2.
Checksum: 79CB125491ECEBA2

FASTA27228,066
        10         20         30         40         50         60 
MTPTFAQAVT ERTLSRRTRL CVGLDPRLGE YRDVAQLRQN TLDVLEASAP YAACVKPQLA 

        70         80         90        100        110        120 
FFEALGLPGF TLLEEVCAAA RTLGLPVLLD GKRGDIGTTA AAYAQGWLGG THAGDALTVN 

       130        140        150        160        170        180 
PFLGFQTLTP FVQAARENGG AIFVLVKTSN PDQQDLQGQG VSERIAVEIA RLGDEEGLGD 

       190        200        210        220        230        240 
GDYASVGAVV GATHPGDLAT FRALMPKALL LLPGLGAQGA QARDLAGAFH AGGTGALASA 

       250        260        270 
SRAVQYARGL DVGAAREAAL ALRDELNGAL GV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF11749.1. Different initiation.
PIRG75302.
RefSeqNP_295922.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RSC5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_2200.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF11749; AAF11749; DR_2200.
GeneID1797499.
KEGGdra:DR_2200.
PATRIC21632090. VBIDeiRad64572_2426.

Phylogenomic databases

eggNOGCOG0284.
KOK01591.
OMADATHHLC.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycDRAD243230:GH46-2246-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_DEIRA
AccessionPrimary (citable) accession number: Q9RSC5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 23, 2002
Last modified: May 14, 2014
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways