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Q9RRC4 (SYR_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase
EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:DR_2568
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus ›

Protein attributes

Sequence length609 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 609609Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151556

Regions

Motif114 – 12411"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q9RRC4 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 5F482073018397BB

FASTA60966,604
        10         20         30         40         50         60 
MDLKAQLKAA VEQAAHQMGM PVDAAIQETP ANKPGDYGTP AAFQMAKAAG GNPAQIAAQL 

        70         80         90        100        110        120 
AQTVVLPAGI RRVEATGPFL NFFLDAGAFV RGVVERPFEL PKREGKVVIE HTSVNPNKEL 

       130        140        150        160        170        180 
HVGHLRNVVL GDSMARILRA AGHTVEVQNY IDDTGRQAAE SLFATQHYGR VWDGVQKYDQ 

       190        200        210        220        230        240 
WLGEGYVQLN ADPQKPELES GIMEIMHKLE AGELRPLVEQ TVKAQLQTCF RLGARYDLLN 

       250        260        270        280        290        300 
WESDVVGSGF LAQAMNILEG SRYTSRPTEG KYAGAFIMDV SEFMPGLEEP NVVLVRSGGT 

       310        320        330        340        350        360 
AMYAAKDIGY QFWKFGLFEG MKFKPFMQDP EGNTIWTSAP DGQPDDERRF GHAQEVINVI 

       370        380        390        400        410        420 
DSRQDHPQTV VRSALGVAGE QEKEERSIHL SYAFVTLEGQ TISGRKGIAV SADDAMDEAQ 

       430        440        450        460        470        480 
KRALSVLQGI NPDLAAREDA AEIARRIGLG AIRFAMLKAE PTRKIDFRWE QALALNGDTA 

       490        500        510        520        530        540 
PYVQYAAVRA ANILKKAEEA GYATDGTGAD WDALPDIDLV LAKQIAKLPE VAAQAARIHS 

       550        560        570        580        590        600 
PHVVAQYALD LATSFNAWYN AKTKQGKPAT NVLQSEEGLR EARLALIVRL RKAFEDTLDL 


IGIEIPAAM

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000513 Genomic DNA. Translation: AAF12109.1.
PIRB75257.
RefSeqNP_296288.1. NC_001263.1.

3D structure databases

ProteinModelPortalQ9RRC4.
ModBaseSearch...

Protein-protein interaction databases

STRING243230.DR_2568.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF12109; AAF12109; DR_2568.
GeneID1798935.
KEGGdra:DR_2568.
PATRIC21632879. VBIDeiRad64572_2813.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMAGEEAMSN.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycDRAD243230:GH46-2931-MONOMER.

Family and domain databases

Gene3D3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase_Ia.
IPR015945. Arg-tRNA-synth_Ia_core.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF55190. Arg-tRNA-synth_Ic_N. 1 hit.
SSF47323. tRNAsyn_1a_bind. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_DEIRA
AccessionPrimary (citable) accession number: Q9RRC4
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: May 1, 2000
Last modified: May 1, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

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