Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9RQ13

- FUCI_BACTN

UniProt

Q9RQ13 - FUCI_BACTN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

L-fucose isomerase

Gene

fucI

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Converts the aldose L-fucose into the corresponding ketose L-fuculose.Curated

Catalytic activityi

L-fucopyranose = L-fuculose.UniRule annotation

Cofactori

Manganese.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei338 – 3381Proton acceptorUniRule annotation
Metal bindingi338 – 3381ManganeseUniRule annotation
Active sitei362 – 3621Proton acceptorUniRule annotation
Metal bindingi362 – 3621ManganeseUniRule annotation
Metal bindingi529 – 5291ManganeseUniRule annotation

GO - Molecular functioni

  1. L-fucose isomerase activity Source: UniProtKB-HAMAP
  2. manganese ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. L-fucose catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Fucose metabolism

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciBTHE226186:GJXV-1295-MONOMER.
UniPathwayiUPA00563; UER00624.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fucose isomeraseUniRule annotation (EC:5.3.1.25UniRule annotation)
Alternative name(s):
6-deoxy-L-galactose isomeraseUniRule annotation
FucIase
Gene namesi
Name:fucIUniRule annotation
Ordered Locus Names:BT_1273
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000001414: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 591591L-fucose isomerasePRO_0000204143Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_1273.

Structurei

3D structure databases

ProteinModelPortaliQ9RQ13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L-fucose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2407.
InParanoidiQ9RQ13.
KOiK01818.
OMAiFWEISDE.
OrthoDBiEOG6FJNCF.

Family and domain databases

Gene3Di3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPiMF_01254. Fucose_iso.
InterProiIPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view]
PfamiPF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view]
SUPFAMiSSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsiTIGR01089. fucI. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RQ13-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKYPKIGIR PTIDGRQGGV RESLEEKTMN LAKAVAELIS NNLKNGDGSP
60 70 80 90 100
VECIIADNTI GRVAESAACA EKFEREGVGS TITVTSCWCY GAETMDMNPH
110 120 130 140 150
YPKAVWGFNG TERPGAVYLA AVLAGHAQKG LPAFGIYGRD VQDLDDNTIP
160 170 180 190 200
EDVAEKILRF ARAAQAVATM RGKSYLSMGS VSMGIAGSIV NPDFFQEYLG
210 220 230 240 250
MRNESIDLTE IIRRMEEGIY DHEEYAKAMA WTEKYCKVNE GEDFKNRPEK
260 270 280 290 300
RKKREQKDAD WEFVVKMMII MRDLMTGNPK LKEMGFKEEA LGHNAIAAGF
310 320 330 340 350
QGQRQWTDFY PNGDYPEALL NTSFDWNGIR EAFVVATEND ACNGVAMLFG
360 370 380 390 400
HLLTNRAQIF SDVRTYWSPE AVKRVTGKEL TGLAANGIIH LINSGATTLD
410 420 430 440 450
GSGQSLDAEG NPVMKEPWNL TDADVENCLK ATTWYPADRD YFRGGGFSSN
460 470 480 490 500
FLSKGGMPVT MMRLNLIKGL GPVLQIAEGW TVEIDPEIHQ KLNMRTDPTW
510 520 530 540 550
PTTWFVPRLC DKSAFKDVYS VMNNWGANHG AISYGHIGQD LITLASMLRI
560 570 580 590
PVCMHNVDEN EIFRPTAWNA FGMDKEGADY RACTTYGPIY K
Length:591
Mass (Da):65,742
Last modified:May 1, 2000 - v1
Checksum:i96B5874825022432
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF137263 Genomic DNA. Translation: AAF01484.1.
AE015928 Genomic DNA. Translation: AAO76380.1.
RefSeqiNP_810186.1. NC_004663.1.
WP_011107686.1. NC_004663.1.

Genome annotation databases

EnsemblBacteriaiAAO76380; AAO76380; BT_1273.
GeneIDi1073391.
KEGGibth:BT_1273.
PATRICi21057387. VBIBacThe70966_1300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF137263 Genomic DNA. Translation: AAF01484.1 .
AE015928 Genomic DNA. Translation: AAO76380.1 .
RefSeqi NP_810186.1. NC_004663.1.
WP_011107686.1. NC_004663.1.

3D structure databases

ProteinModelPortali Q9RQ13.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 226186.BT_1273.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO76380 ; AAO76380 ; BT_1273 .
GeneIDi 1073391.
KEGGi bth:BT_1273.
PATRICi 21057387. VBIBacThe70966_1300.

Phylogenomic databases

eggNOGi COG2407.
InParanoidi Q9RQ13.
KOi K01818.
OMAi FWEISDE.
OrthoDBi EOG6FJNCF.

Enzyme and pathway databases

UniPathwayi UPA00563 ; UER00624 .
BioCyci BTHE226186:GJXV-1295-MONOMER.

Family and domain databases

Gene3Di 3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPi MF_01254. Fucose_iso.
InterProi IPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view ]
Pfami PF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view ]
SUPFAMi SSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsi TIGR01089. fucI. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem."
    Hooper L.V., Xu J., Falk P.G., Midtvedt T., Gordon J.I.
    Proc. Natl. Acad. Sci. U.S.A. 96:9833-9838(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.
  2. "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
    Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
    Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Entry informationi

Entry nameiFUCI_BACTN
AccessioniPrimary (citable) accession number: Q9RQ13
Secondary accession number(s): Q7C426
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3