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Protein

Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058

Gene

BRA0058

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

The VirB system could be required for the establishment of the replication niche in the host.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Virulence

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058
Gene namesi
Ordered Locus Names:BRA0058, BS1330_II0058
OrganismiBrucella suis biovar 1 (strain 1330)
Taxonomic identifieri204722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000007104 Componenti: Chromosome II

Subcellular locationi

  • Cell outer membrane Curated; Lipid-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1515PROSITE-ProRule annotationAdd
BLAST
Chaini16 – 172157Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058PRO_0000291448Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi16 – 161N-palmitoyl cysteinePROSITE-ProRule annotation
Lipidationi16 – 161S-diacylglycerol cysteinePROSITE-ProRule annotation

Keywords - PTMi

Lipoprotein, Palmitate

Expressioni

Inductioni

Specifically induced within macrophages by phagosome acidification. Induced at 37 degrees Celsius in minimal medium, suggesting that nutritional stress is a regulating signal.

Structurei

3D structure databases

ProteinModelPortaliQ9RPX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini58 – 172115OmpA-likePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 OmpA-like domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG2885.
HOGENOMiHOG000289240.
OMAiNSQMAVE.
OrthoDBiEOG6PP9QB.

Family and domain databases

Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006665. OmpA/MotB_C.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiPS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9RPX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTLVMVACA VSLAACSSPP KPPTVSGRHR IPINSPAAQE ELRLQVFPQE
60 70 80 90 100
PTAQATMWPA RPPKQTVSVY FPQDVTVFRP TSAQINQLHT LLWPVPKHIN
110 120 130 140 150
VRGLTDNNCP PPGDTQVARV RALAIYNWLI NQGVSASRIT ISYAPVKDYA
160 170
SNAPLSPGRV LNRRVDIEIL RK
Length:172
Mass (Da):18,991
Last modified:May 1, 2000 - v1
Checksum:i0A71CF3C0BB074C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF141604 Genomic DNA. Translation: AAD56622.1.
AE014292 Genomic DNA. Translation: AAN33270.1.
CP002998 Genomic DNA. Translation: AEM19550.1.
RefSeqiNP_699265.1. NC_004311.2.
WP_004689960.1. NZ_KN046805.1.
YP_005613776.1. NC_017250.1.

Genome annotation databases

EnsemblBacteriaiAAN33270; AAN33270; BRA0058.
AEM19550; AEM19550; BS1330_II0058.
KEGGibms:BRA0058.
bsi:BS1330_II0058.
PATRICi17792919. VBIBruSui107850_2278.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF141604 Genomic DNA. Translation: AAD56622.1.
AE014292 Genomic DNA. Translation: AAN33270.1.
CP002998 Genomic DNA. Translation: AEM19550.1.
RefSeqiNP_699265.1. NC_004311.2.
WP_004689960.1. NZ_KN046805.1.
YP_005613776.1. NC_017250.1.

3D structure databases

ProteinModelPortaliQ9RPX3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN33270; AAN33270; BRA0058.
AEM19550; AEM19550; BS1330_II0058.
KEGGibms:BRA0058.
bsi:BS1330_II0058.
PATRICi17792919. VBIBruSui107850_2278.

Phylogenomic databases

eggNOGiCOG2885.
HOGENOMiHOG000289240.
OMAiNSQMAVE.
OrthoDBiEOG6PP9QB.

Family and domain databases

Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006665. OmpA/MotB_C.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
SUPFAMiSSF103088. SSF103088. 1 hit.
PROSITEiPS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis."
    O'Callaghan D., Cazevieille C., Allardet-Servent A., Boschiroli M.L., Bourg G., Foulongne V., Frutos P., Kulakov Y., Ramuz M.
    Mol. Microbiol. 33:1210-1220(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 1330.
  2. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], EXPRESSION CONDITIONS.
    Strain: 1330.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1330.

Entry informationi

Entry nameiYU58_BRUSU
AccessioniPrimary (citable) accession number: Q9RPX3
Secondary accession number(s): G0KEQ6, Q7CEG5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: May 1, 2000
Last modified: June 24, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Transcription of the operon is maximal in early exponential phase.

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella suis
    Brucella suis (strain 1330): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.