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Q9RPX3

- YU58_BRUSU

UniProt

Q9RPX3 - YU58_BRUSU

Protein

Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058

Gene

BRA0058

Organism
Brucella suis biovar 1 (strain 1330)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    The VirB system could be required for the establishment of the replication niche in the host.

    GO - Biological processi

    1. pathogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Virulence

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058
    Gene namesi
    Ordered Locus Names:BRA0058, BS1330_II0058
    OrganismiBrucella suis biovar 1 (strain 1330)
    Taxonomic identifieri204722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000824: Chromosome II, UP000007104: Chromosome II

    Subcellular locationi

    Cell outer membrane Curated; Lipid-anchor PROSITE-ProRule annotation

    GO - Cellular componenti

    1. cell outer membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell outer membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1515PROSITE-ProRule annotationAdd
    BLAST
    Chaini16 – 172157Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058PRO_0000291448Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi16 – 161N-palmitoyl cysteinePROSITE-ProRule annotation
    Lipidationi16 – 161S-diacylglycerol cysteinePROSITE-ProRule annotation

    Keywords - PTMi

    Lipoprotein, Palmitate

    Expressioni

    Inductioni

    Specifically induced within macrophages by phagosome acidification. Induced at 37 degrees Celsius in minimal medium, suggesting that nutritional stress is a regulating signal.

    Interactioni

    Protein-protein interaction databases

    STRINGi204722.BRA0058.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9RPX3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini58 – 172115OmpA-likePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 OmpA-like domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG2885.
    HOGENOMiHOG000289240.
    OrthoDBiEOG6PP9QB.

    Family and domain databases

    Gene3Di3.30.1330.60. 1 hit.
    InterProiIPR006665. OmpA/MotB_C.
    [Graphical view]
    PfamiPF00691. OmpA. 1 hit.
    [Graphical view]
    SUPFAMiSSF103088. SSF103088. 1 hit.
    PROSITEiPS51123. OMPA_2. 1 hit.
    PS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9RPX3-1 [UniParc]FASTAAdd to Basket

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    MRTLVMVACA VSLAACSSPP KPPTVSGRHR IPINSPAAQE ELRLQVFPQE    50
    PTAQATMWPA RPPKQTVSVY FPQDVTVFRP TSAQINQLHT LLWPVPKHIN 100
    VRGLTDNNCP PPGDTQVARV RALAIYNWLI NQGVSASRIT ISYAPVKDYA 150
    SNAPLSPGRV LNRRVDIEIL RK 172
    Length:172
    Mass (Da):18,991
    Last modified:May 1, 2000 - v1
    Checksum:i0A71CF3C0BB074C8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF141604 Genomic DNA. Translation: AAD56622.1.
    AE014292 Genomic DNA. Translation: AAN33270.1.
    CP002998 Genomic DNA. Translation: AEM19550.1.
    RefSeqiNP_699265.1. NC_004311.2.
    YP_005613776.1. NC_017250.1.

    Genome annotation databases

    EnsemblBacteriaiAAN33270; AAN33270; BRA0058.
    AEM19550; AEM19550; BS1330_II0058.
    GeneIDi1164495.
    12139492.
    KEGGibms:BRA0058.
    bsi:BS1330_II0058.
    PATRICi17792919. VBIBruSui107850_2278.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF141604 Genomic DNA. Translation: AAD56622.1 .
    AE014292 Genomic DNA. Translation: AAN33270.1 .
    CP002998 Genomic DNA. Translation: AEM19550.1 .
    RefSeqi NP_699265.1. NC_004311.2.
    YP_005613776.1. NC_017250.1.

    3D structure databases

    ProteinModelPortali Q9RPX3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 204722.BRA0058.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN33270 ; AAN33270 ; BRA0058 .
    AEM19550 ; AEM19550 ; BS1330_II0058 .
    GeneIDi 1164495.
    12139492.
    KEGGi bms:BRA0058.
    bsi:BS1330_II0058.
    PATRICi 17792919. VBIBruSui107850_2278.

    Phylogenomic databases

    eggNOGi COG2885.
    HOGENOMi HOG000289240.
    OrthoDBi EOG6PP9QB.

    Family and domain databases

    Gene3Di 3.30.1330.60. 1 hit.
    InterProi IPR006665. OmpA/MotB_C.
    [Graphical view ]
    Pfami PF00691. OmpA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103088. SSF103088. 1 hit.
    PROSITEi PS51123. OMPA_2. 1 hit.
    PS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis."
      O'Callaghan D., Cazevieille C., Allardet-Servent A., Boschiroli M.L., Bourg G., Foulongne V., Frutos P., Kulakov Y., Ramuz M.
      Mol. Microbiol. 33:1210-1220(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 1330.
    2. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], EXPRESSION CONDITIONS.
      Strain: 1330.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1330.

    Entry informationi

    Entry nameiYU58_BRUSU
    AccessioniPrimary (citable) accession number: Q9RPX3
    Secondary accession number(s): G0KEQ6, Q7CEG5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 12, 2007
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Transcription of the operon is maximal in early exponential phase.

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella suis
      Brucella suis (strain 1330): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3