Q9RNH6 (GLGA_RHOS4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	RHOS4_14780
ORF Names:	RSP_2885

Organism

Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Reference proteome] [HAMAP]

Taxonomic identifier

272943 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter › Rhodobacter sphaeroides

Protein attributes

Sequence length	478 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Sequence caution	The sequence AAD53959.1 differs from that shown. Reason: Erroneous initiation. The sequence ABA79046.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 478	478	Glycogen synthase HAMAP-Rule MF_00484		PRO_0000188642
Sites
	Binding site	20	1	ADP-glucose By similarity
Experimental info
	Sequence conflict	97 – 99	3	EGG → GR in AAD53959. Ref.1
	Sequence conflict	124 – 132	9	RIAREGLGD → GSRARGSGT in AAD53959. Ref.1
	Sequence conflict	190	1	E → K in AAD53959. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9RNH6 [UniParc]. Last modified January 24, 2006. Version 3. Checksum: 403178D5CBF44F71	FASTA	478	50,962
	10 20 30 40 50 60 METARGRVLS VASECVPLLK TGGLADVVGA LPGALAAEGW EMRVLMPCYR PLKWRLEEME 70 80 90 100 110 120 EVFAEEDLFG GPGRVMAGEV AGRKMLLLDA PHLYDREGGP YAGPDGDWGD NAQRFAALSW 130 140 150 160 170 180 IGARIAREGL GDGWRPDVVH AHDWQAGFTP AYMNYWGSGG ASSVLTVHNI AFQGWAPASL 190 200 210 220 230 240 LSALRLPPQE FHPAALEYYG GLSSLKAGLV SADHITTVSP TYACELMRPE FGMGLQGVIA 250 260 270 280 290 300 QRAGQVTGIL NGVDTDIWSP EVEERPYDAE SLKAKAENRA VLSGAFKLSV PGPLAILVSR 310 320 330 340 350 360 LTYQKGIDLI PEVLPDFIAA GGGLAVLGTG DAPLEAAMRE LEVRFPGRVG VRIGYDEGLS 370 380 390 400 410 420 HLMFAGGDAV LVPSRFEPCG LTQMYGLRYG AIPVVALTGG LADTIINANP AAMAAGCATG 430 440 450 460 470 LTFHPTEPPA FAEALRRLIH LYADPAAWET VQRNAMRHPV GWETSAAAYA ALYRELVA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, sequencing, and expression of the ADP-glucose pyrophosphorylase gene (glgC) from Rhodobacter sphaeroides 2.4.1." Igarashi R.Y., Meyer C.R. Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF181035 Genomic DNA. Translation: AAD53959.1. Different initiation. CP000143 Genomic DNA. Translation: ABA79046.1. Different initiation.
RefSeq	YP_352947.1. NC_007493.1.
3D structure databases
ProteinModelPortal	Q9RNH6.
ModBase	Search...
Protein-protein interaction databases
STRING	272943.RSP_2885.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3720625.
KEGG	rsp:RSP_2885.
PATRIC	23152869. VBIRhoSph57909_1821.
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HOG000294941.
KO	K00703.
ProtClustDB	PRK00654.
Enzyme and pathway databases
BioCyc	RSPH272943:GJAS-1513-MONOMER.
UniPathway	UPA00164.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth.
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_RHOS4

Accession

Primary (citable) accession number: Q9RNH6
Secondary accession number(s): Q3J2D8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	January 24, 2006
Last modified:	May 1, 2013
This is version 67 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program