Reviewed, UniProtKB/Swiss-Prot Q9RMC1 (G6PI_ACILW)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:

pgi

Organism

Acinetobacter lwoffii

Taxonomic identifier

28090 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	557 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 557	557	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000180579
Sites
	Active site	361	1	Proton donor By similarity
	Active site	392	1	By similarity
	Active site	520	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9RMC1-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2D4FABC1AB595D26	FASTA	557	62,671
	10 20 30 40 50 60 MNYKQPLIVK SQQQALSALR NLKMQTQDTH LNQFFSDDSG RFERFSVEQE QLVLDFSKHR 70 80 90 100 110 120 IDQNVLNGLV DLAHAQDLTQ WIQRLFSLEE INYTEQRAAM HWALRVPEQN QQVLPEITAQ 130 140 150 160 170 180 VHTQLERMYS LVEKIHAGQY RGATGEVIQD VVNIGVGGSD LGPLMVTHAL SDFKVVTAKP 190 200 210 220 230 240 LDVHFVSTMD GSQLSDLLHQ LRPETTLFII SSKSFGTIDT LSNAQTVRQW LEKALGKNSH 250 260 270 280 290 300 VLKHHFIGVS TKPDKMSEWG IAPENQLLLW DWVGGRYSLW SCIGLPIALT VGVDGFKQLL 310 320 330 340 350 360 SGAYAIDQHF QTAPFAQNIP VLIGLLGVWN NNFLDIQTHA VLPYDGRLKY FAAYLQQLEM 370 380 390 400 410 420 ESNGKSTQRS GEKVDSATCP IVWGEVGPNA QHAFYQLLHQ GTHKVSCDFI APVKRYNANH 430 440 450 460 470 480 FTYAENAEAL IEQHHLALSN CLAQSRLLAF GNQALTADEI EDLPTYKQYE GNQPSSTILL 490 500 510 520 530 540 KELNPYSLGM LIATYEHKVF VQSVLWNINP FDQWGVEKGK EIANQLLPIL NREQDDLSTF 550 DASTQGLLKI LLGKNNG

References

[1]	"Genomic organization of the wce region of Acinetobacter lwoffii RAG-1 required for emulsan biosynthesis." Nakar D., Gutnick D.L. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: RAG-1 / ATCC 31012.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ243431 Genomic DNA. Translation: CAB57211.1.
PIR	T44843.
3D structure databases
SMR	Q9RMC1. Positions 15-553.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.3.1.9. 96146.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_ACILW

Accession

Primary (citable) accession number: Q9RMC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 2, 2001
Last sequence update:	May 1, 2000
Last modified:	January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)