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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Acinetobacter lwoffii
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei361 – 3611Proton donorBy similarity
Active sitei392 – 3921By similarity
Active sitei520 – 5201By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
OrganismiAcinetobacter lwoffii
Taxonomic identifieri28090 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 557557Glucose-6-phosphate isomerasePRO_0000180579Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9RMC1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9RMC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYKQPLIVK SQQQALSALR NLKMQTQDTH LNQFFSDDSG RFERFSVEQE
60 70 80 90 100
QLVLDFSKHR IDQNVLNGLV DLAHAQDLTQ WIQRLFSLEE INYTEQRAAM
110 120 130 140 150
HWALRVPEQN QQVLPEITAQ VHTQLERMYS LVEKIHAGQY RGATGEVIQD
160 170 180 190 200
VVNIGVGGSD LGPLMVTHAL SDFKVVTAKP LDVHFVSTMD GSQLSDLLHQ
210 220 230 240 250
LRPETTLFII SSKSFGTIDT LSNAQTVRQW LEKALGKNSH VLKHHFIGVS
260 270 280 290 300
TKPDKMSEWG IAPENQLLLW DWVGGRYSLW SCIGLPIALT VGVDGFKQLL
310 320 330 340 350
SGAYAIDQHF QTAPFAQNIP VLIGLLGVWN NNFLDIQTHA VLPYDGRLKY
360 370 380 390 400
FAAYLQQLEM ESNGKSTQRS GEKVDSATCP IVWGEVGPNA QHAFYQLLHQ
410 420 430 440 450
GTHKVSCDFI APVKRYNANH FTYAENAEAL IEQHHLALSN CLAQSRLLAF
460 470 480 490 500
GNQALTADEI EDLPTYKQYE GNQPSSTILL KELNPYSLGM LIATYEHKVF
510 520 530 540 550
VQSVLWNINP FDQWGVEKGK EIANQLLPIL NREQDDLSTF DASTQGLLKI

LLGKNNG
Length:557
Mass (Da):62,671
Last modified:April 30, 2000 - v1
Checksum:i2D4FABC1AB595D26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243431 Genomic DNA. Translation: CAB57211.1.
PIRiT44843.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243431 Genomic DNA. Translation: CAB57211.1.
PIRiT44843.

3D structure databases

ProteinModelPortaliQ9RMC1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic organization of the wce region of Acinetobacter lwoffii RAG-1 required for emulsan biosynthesis."
    Nakar D., Gutnick D.L.
    Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: RAG-1 / ATCC 31012.

Entry informationi

Entry nameiG6PI_ACILW
AccessioniPrimary (citable) accession number: Q9RMC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 2001
Last sequence update: April 30, 2000
Last modified: January 6, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.