Q9RM48 (Q9RM48_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lymphostatin EMBL CAB55629.1

Gene names

Name:

lifA EMBL CAB55629.1

Organism

Escherichia coli EMBL CAB55629.1

Taxonomic identifier

562 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	3223 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Gene Ontology (GO)
Biological process	pathogenesis Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9RM48 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 03E45ECDED7938C1	FASTA	3,223	365,969
	10 20 30 40 50 60 MRLPEKVLFP PVTSGLSGQE KQKKPKSITG FQENYQRNIR PIKTASEARL RFFDKMVSKE 70 80 90 100 110 120 NSLEDVVSLG EMIQKEIYGH EQRTFSPVHH TGNWKSSLLH NALLGLANVY NGLRETEYPN 130 140 150 160 170 180 TFNRDGIKST NSFRDNLLTK TRTPRDNFEE GIKHPEHATI PYDNDNESNK LLKAGKIAGN 190 200 210 220 230 240 NNELLMEIKK ESQSDHQIPL SDKFLKRKKR SPVAEDKVQN SLTPENFVQK ISLSDELKTK 250 260 270 280 290 300 YANEIIEIKR IMGEYNLLPD KNSRNGLKLL QKQADLLKII MEDTSVTENT FKNIEIAITD 310 320 330 340 350 360 IKREYYSHTV DIEKNIHAIW VAGSPPESIS DYIKTFLKTY KEFTYYLWVD EKAFGAAKFT 370 380 390 400 410 420 SVLKQIAFDL ACRTIQQNTP QKNIDFINLY NEIRKKYNNN PSGQQEYLNK LRELYATYQK 430 440 450 460 470 480 ISTPLKHMFN SFFLENMIKL QDNFFNYCIV KGVTEINDEL RINYLKNVIK LSDDDIGNYQ 490 500 510 520 530 540 KTINDNKDRV KKLILDLQKQ FGENRISIKD VNSLTSLSKS ENNHNYQTEM LLRWNYPAAS 550 560 570 580 590 600 DLLRMYILKE HGGIYTDTDM MPAYSKQVIF KIMMQTNGDN RFLEDLKLRR AISDGVLRYV 610 620 630 640 650 660 NNQNIDEVNY NEISDADKNI IKKILTEISK MPEDSIFTKI NTRIPRDTMP ILRRYHLWPD 670 680 690 700 710 720 GWNIRGLNGF MLSHKGSEVI DAVIAGQNQA YRELRRIRDN IHSEIYFKQT DELSSLPDTD 730 740 750 760 770 780 KIGGILVKKY LSGSLFSKFR QDTIIPEALS TLQISGPDLI QRKMLQFFRS RGVLGEEFIN 790 800 810 820 830 840 ERKLSDKAYI GVYKTTGTGK YDWLTPESIG VNDVTPADES TWCIGKGRCV DDFLFKDVST 850 860 870 880 890 900 LKTENLPELF LTKIDTDTFF SQWSTKTKKD LQKKIQDLTV RYNELIDSST IDFKNLYEID 910 920 930 940 950 960 QMLHMIMLEM NDDIAKRSLF SLQVQISEKI RRMTIPVDNI INIYPDLHKK NDNDLSMSIK 970 980 990 1000 1010 1020 GFLASNPHTK INILYSNKTE HNIFIKDLFS FAVMENELRD IINNMSKDKT PENWEGRVML 1030 1040 1050 1060 1070 1080 QRYLELKMKD HLSLQSSQEA NEFLEISTFI YENDFLREKI EAVKNKMNSH ELYFEKIKKE 1090 1100 1110 1120 1130 1140 QNTWQDLSTK EQKLQLIKAL KEISGNTEKD SHYDRLLDAF FKKHNENIHN KIQRIKDEFK 1150 1160 1170 1180 1190 1200 EYSRVAIHNI DKVIFKGQTL DRLYHEGYVF SDINTLSRYT LHGLGITGVH TEENLLPAPS 1210 1220 1230 1240 1250 1260 SSLINILKEH YNEDEISAKL PLAYDYILNK KESSSIPVEI LNKLSELPPH ELLTPVLGQS 1270 1280 1290 1300 1310 1320 VNPLGMGYSS DNGKITEQVI VSGADGFDNP ISGLIYTYLE DLYNIHVRMR EGTLNSQNLR 1330 1340 1350 1360 1370 1380 QLLENSVSSC FLTEQSINKL LSEAEKRPYQ SLTEIHQHLT GLPTIADATL SLLSVGLPGT 1390 1400 1410 1420 1430 1440 GKLLRREQDY GRPPVTAIQD STFVLPYNFK GIGFNDNIIS SAPVASSLHF IAEHAKYTLL 1450 1460 1470 1480 1490 1500 SWPEFYRHHA QRWFEMAKGY GSQNIDFHPQ SLLVTQEGRC MGLALLYLQT EDTAHYSILQ 1510 1520 1530 1540 1550 1560 ENLMTVSALH QTSNRDKLPL SKDDNSLMTR TYSLIEMLQY QGNKYITNES LLHKTAWNQE 1570 1580 1590 1600 1610 1620 RITLLFNEKG VKRALISTPN HTLVLQQLED IYRLTDPNFG HADFLSPIDA LKFIEAMIQL 1630 1640 1650 1660 1670 1680 TPTLQEYYGL LNKDINKHIQ VHYAESDMVW NKLLPENDAG LSTRIQHTTT DRLANLAEPV 1690 1700 1710 1720 1730 1740 AVAGISLPVK TLYDIGATLD GRRITSPPTS EQIPSLRLNG DVLNDYLSRT VLTPEQADNI 1750 1760 1770 1780 1790 1800 RKILHTQGIR SGTRPIDPEM IRGTQDDLVS SQTRLQRQAT RVKQQLAGVL DTLQQHFQNI 1810 1820 1830 1840 1850 1860 PRSSGRHLSV ENIELADIGS GRFNLQIRDG ETLHTTSVEV PEVVSRFQKL STMLSALPAS 1870 1880 1890 1900 1910 1920 GIMDFDLGMS VVGVVQYARL LQQGHEDSTL AKINLAMDIK QLSEATLGSM IQIAGNKFLN 1930 1940 1950 1960 1970 1980 TEGIQGFRLE SAVAEGMRSV ATRTGGTMGK ALSASARVLE LPVLETVLGT WNLYNSVIQL 1990 2000 2010 2020 2030 2040 QQATSYSETM AARVQIAFDS ISLGLTAASV AFPPLIIATG PIAAIGMGAS SIARNVARKE 2050 2060 2070 2080 2090 2100 ERHTQWLEYK KFLTDGSKHI VVASPERGLL DFSGNKVFGK MVLDLRQSPP LLHGESSFNA 2110 2120 2130 2140 2150 2160 DRKIGHRPDL GDWQIREKVG YANSISPYSS LAHGYANSKW PRTIPKIPSG EYDTIILGYG 2170 2180 2190 2200 2210 2220 HQYQANTEIE YLSNWIVWRE AVPDSTSRHK RPPLEVLNSQ CTVIAGERKT TVLPLRVLSD 2230 2240 2250 2260 2270 2280 LTPECTEQAI SLKDYKFILR GGSGGLAVQV GGAGYYDIDA NLVAKENTLS FRGLPEEFPL 2290 2300 2310 2320 2330 2340 TFDLSKQTQS VMLKTPDDEV PVMTITQKGI NTLVGTAAGK DRLIGNDKDN TFHTSSGGGT 2350 2360 2370 2380 2390 2400 VISGGGNNRY IIPRDLKTPL TLTLSSNSVS HEIFLPETTL AELKPVAFEL SLIYWAGNNI 2410 2420 2430 2440 2450 2460 NVQPEDEAKL NHFAGNFRVH TRDGMTLEAV SRENGIQLAI SLCDVQRWQA VYPEENNRPD 2470 2480 2490 2500 2510 2520 AILDRLHDMG WSLTPEVRFQ GGETQVSYDP LTRQLVYQLQ ARYSEFQLAG SRHHTTAVTG 2530 2540 2550 2560 2570 2580 TPGSRYIIMK PVTTQILPTQ IILAGDNDHP ETIDLLEASP VLVEGKKDKN SVILTIATIQ 2590 2600 2610 2620 2630 2640 YSLQLTISGI EESLPETTRV AIQPQDTRLL GDVLRILPDN GNWVGIFRSG HTPTVNRLEN 2650 2660 2670 2680 2690 2700 LMALNQVMTF LPRVSGSAEQ VLCLENLGGV RKKVEGELLS GKLKGAWKAE GEPTVPVNIS 2710 2720 2730 2740 2750 2760 DLSIPPYSRL YLIFEGKNNV LLRSKVHAAP LKITSAGEMQ LSERQWQQQE HIIVKPDNEA 2770 2780 2790 2800 2810 2820 PSLILSEFRR FTISSDKTFS LKLMCHQGMV RIDRRSLSVR LFYLREQPGI GSLRLTFRDF 2830 2840 2850 2860 2870 2880 FTEVMDTTDR EILEKELRPI LIGDTHRFIN AAYKNHLNIQ LGDGVLNLAD IVAEYARIQK 2890 2900 2910 2920 2930 2940 EETSKILYQY QGAMKKKTDG PSVVEDAIMT TTVTTDSGEL FPTFHPWYTD DLSGRYKSVP 2950 2960 2970 2980 2990 3000 MARKADTLYH LTPKGDLQII YQVATKMVNQ AMIVSLPNYR HEWEKYNLSI LSEIPQNNNT 3010 3020 3030 3040 3050 3060 VVHSILRVNG PTMQVRTIDY RGTDENNPIV SFSDTTFING EQMLSYDSHS SGRVYSREEY 3070 3080 3090 3100 3110 3120 MMWELQQRVS EASSARTQDY WLMDAAVRNG EWKITPELLR HTPGYIRSTV SKWSRGWLKT 3130 3140 3150 3160 3170 3180 GTILQTPEDR NTDVYLTTIQ NNVFSRQGGG YQVYYRIDGM AGADIADNAP GETRCTLRPG 3190 3200 3210 3220 TCFEVTSVDE RHYEWNIIYV TLKTCGWSRN GQSKTPNGDN LFN

References

[1]

"A large toxin from pathogenic Escherichia coli strains that inhibits lymphocyte activation." Klapproth J.M., Scaletsky I.C., McNamara B.P., Lai L.C., Malstrom C., James S.P., Donnenberg M.S. Infect. Immun. 68:2148-2155(2000) [PubMed: 10722613] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: E2348/69 EMBL CAB55629.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ133705 Genomic DNA. Translation: CAB55629.1.
3D structure databases
ProteinModelPortal	Q9RM48.
ModBase	Search...
Protein family/group databases
CAZy	GT44. Glycosyltransferase Family 44.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR021882. DUF3491. IPR007577. GlycoTrfase_DXD_sugar-bd_CS. IPR006473. Peptidase_C58_Yopt. IPR024772. TcdA/TcdB_N. [Graphical view]
Pfam	PF11996. DUF3491. 1 hit. PF04488. Gly_transf_sug. 1 hit. PF12918. TcdB_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01586. YopT_cys_prot. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9RM48_ECOLX

Accession

Primary (citable) accession number: Q9RM48

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)