Reviewed, UniProtKB/Swiss-Prot Q9RLM3 (T2D1_NEIMC)

Names and origin

Protein names

Recommended name:
    Putative type-2 restriction enzyme NmeDIP
      Short name=R.NmeDIP
    EC=3.1.21.4
Alternative name(s):
    Type II restriction enzyme NmeDIP
    Endonuclease NmeDIP

Gene names

Name:

nmeDIRP

Organism

Neisseria meningitidis serogroup C

Taxonomic identifier

135720 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Predicted.

General annotation (Comments)

Catalytic activity

Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Ontologies

Keywords
Biological process	Restriction system
Molecular function	Endonuclease Hydrolase Nuclease
Gene Ontology (GO)
Biological process	DNA restriction-modification system Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	Type II site-specific deoxyribonuclease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 351	351	Putative type-2 restriction enzyme NmeDIP		PRO_0000077351

Sequences

	Sequence		Length	Mass (Da)
	Q9RLM3-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: E65509848A6FEB07	FASTA	351	39,712
	10 20 30 40 50 60 MSGQKLTAAN LVSAIDSLKK NVNYNYVNSS NTHTIQIVHV EKPEGPIKIK RGDTETSISK 70 80 90 100 110 120 QAIWRLADAL STGEPVNVDR VFGASYNFRS ALEALLAHTP EIYWCKLQRI QPGLNKSEVV 130 140 150 160 170 180 EGHKHIIWLP DRPHEKGVMK EYETDVVISE IPSNNVVYDA LSLPSTHSEI DIDVKRRHVQ 190 200 210 220 230 240 IQIALSAIGF QLGFRTWIAR NDQGISYGDK KIADLDGIVQ KIESEKLISS FDGAVQAAMN 250 260 270 280 290 300 IDCIWFRNGK LMPAVMEVEH STGVRSGLAR MKQLKDLLPP YANTRWVIVA PDEDRDKVFK 310 320 330 340 350 EANVPMFKNL DTQYFPYSAV EELYSLCIRR KLTNKAVNEE FLDCFMEKCV M

References

[1]

"Differential distribution of novel restriction-modification systems in clonal lineages of Neisseria meningitidis." Claus H., Friedrich A., Frosch M., Vogel U. J. Bacteriol. 182:1296-1303(2000) [PubMed: 10671450] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 2120 / Serogroup C / Serotype NT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ238948 Genomic DNA. Translation: CAB59898.1.
3D structure databases
ModBase	Search...
Protein family/group databases
REBASE	4187. NmeDI.
Enzyme and pathway databases
BRENDA	3.1.21.4. 298707.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

T2D1_NEIMC

Accession

Primary (citable) accession number: Q9RLM3

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 3, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)